Firooz Alireza; Handjani Farhad; Lajevardi Vahideh; Mansouri Parvin; Nassiri-Kashani Mansour; Norouzi Yasaman
Abstract
Urticaria is a common and challenging skin disorder. Diagnosis and treatment of urticaria is not limited to the field of dermatology. General physicians, allergologists and clinical immunologists are also commonly involved in the management of patients with urticaria. Iranian Society of Dermatology developed ...
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Urticaria is a common and challenging skin disorder. Diagnosis and treatment of urticaria is not limited to the field of dermatology. General physicians, allergologists and clinical immunologists are also commonly involved in the management of patients with urticaria. Iranian Society of Dermatology developed a clinical practice guideline concerning diagnosis and treatment of urticaria that was published in 2015. The current guideline is an update to the previous one and includes findings related to this subject which has been published in the medical literature from 2015 to August 2018.
Nassiri-Kashani Mansour; Nassiri-Kashani Mohammad Hassan; Khatami Alireza; Ghafari Mostafa; Firooz Alireza; Dowlati Yahya
Volume 17, Issue 2 , 2014, , Pages 49-53
Abstract
Background: Job-related allergic contact dermatitis (ACD) mayprolong the disease duration, increase disabilities, and decreasethe patient’s quality of life. The aim of this study was to determinecommon allergens causing ACD, investigating certain featuresof the disease and evaluating its relation ...
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Background: Job-related allergic contact dermatitis (ACD) mayprolong the disease duration, increase disabilities, and decreasethe patient’s quality of life. The aim of this study was to determinecommon allergens causing ACD, investigating certain featuresof the disease and evaluating its relation to the patients’ jobs.Method: In this cross-sectional study, relevant data was obtainedfrom patch test clinics at the Center for Research and Trainingin Skin Diseases and Leprosy, Tehran University of MedicalSciences, and two private dermatology clinics in Tehran, Iran.Nine hundred and forty six patients from different regions of Iranwith a probable diagnosis of ACD were recruited into the study.Patch testing was used as the gold standard test to differentiateACD from other differential diagnoses.Result: Of 946 studied patients with a probable diagnosis ofACD, 649 (68.6%) cases were females. The mean age ± standarddeviation (SD) of the patients was 31.9 ± 12.3 years. Five hundredand twenty eight (55.7%) cases had positive patch test results toat least one tested allergen. Comparing job-related and non jobrelatedACD patients revealed that while there was a significantdifference in the mean age of the two group (30.6 ± 11.3 vs.32.7 ± 12.9 years in job-related and non-job-related groups,respectively) (P=0.016), there were no significant differences inthe gender distribution, number of positive patch tests, frequencyof allergens, reaction time, and severity of reactions between thetwo groups. Nickel sulphate and cobalt chloride were the twomost common allergens in both groups.Conclusion: Job-related patients were younger and most of themwere female compared to non job-related patients. However,other characteristics were not different between the two groups.
Firooz Alireza; Nassiri-Kashani Mansour; Gorouhi Farzam; Davari Parastoo; Yaghoubi Reza; Farshchian Mahmoud; Esfandiarpour Iraj; Golchai Mohammad Javad; Dowlati Yahya
Volume 10, Issue 3 , 2007, , Pages 187-195
Abstract
Background and aim: The frequency of sensitization to contact allergens varies in different countries because of both genetic and, more importantly, allergen exposure variations. The objective is to determine the frequency of sensitization to contact allergens in Iranian patients with dermatitis.Materials ...
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Background and aim: The frequency of sensitization to contact allergens varies in different countries because of both genetic and, more importantly, allergen exposure variations. The objective is to determine the frequency of sensitization to contact allergens in Iranian patients with dermatitis.Materials and methods: Four hundreds and one patients with a clinical diagnosis of contact dermatitis and/or atopic dermatitis were evaluated with a 24-allergen European standard series in four major cities in Iran. The patches were applied on the back of the patients, removed after 24 hours and the readings were taken on 24, 48 and 72 hours after application.Results: One hundred and seventy six patients (43.8%) showed at least 1 positive reaction with a total positive reactions of 268, and 64 patients (15.9%) had 2 or more positive reactions. The 5 most common allergens were nickel sulfate [64 (15.9%)], potassium dichromate [40 (10.0%)], thiuram mix [27 (6.7%)], cobalt chloride [23 (5.7%)], and Balsam of Peru [17 (4.2%)]. Contact allergy to nickel sulfate was significantly more common in female patients and in patients under 40 years of age (P<0.001).Conclusion: Nickel sulfate is the most common contact allergen in Iran, mostly affecting women and younger patients probably because of more exposure. Thiuram had a significant increase in its prevalence during the previous years and further studies need to distinguish its causes.