Edalatkhah Hassan; Matin Elmira; Ahari Saeid Sadeghieh
Volume 20, Issue 2 , 2017, , Pages 54-58
Abstract
Background: Acne vulgaris has a multifactorial pathogenesis; however, the exact role of genetic predisposition is not clear. Some studies have reported an association between familiy historyof acne and moderate to severe acne. In this study, we investigated the relationship between familiy history and ...
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Background: Acne vulgaris has a multifactorial pathogenesis; however, the exact role of genetic predisposition is not clear. Some studies have reported an association between familiy historyof acne and moderate to severe acne. In this study, we investigated the relationship between familiy history and prevalence of acne vulgaris in girls 8 to 13 years of age.Methods: This case-control study enrolled 400 students. The participants were divided into two groups, case and control, with 200 students per group. The case group consisted of students with acne vulgaris and the control group included those without acne. The severity of acne was determined based on the Global AcneGrading Score (GAGS). The presence of acne in close relatives (father, mother, sister, brother) was determined through face to face interviews with participants’ mothers and phone contacts with other family members. All collected data were analyzed by SPSS software.Results: The case participants had a mean age of 10.62±1.71 years and those in the control group had a mean age of 10.54±1.70 years, which was not statistically significant. The mothers with acne vulgaris had the highest odds ratio (OR: 2.719, 95% CI: 1.788-4.133) between the case and the control groups. The ratio of encountering the probability with both parents developing acne vulgaris between the two groups was 2.346 (95% CI: 1.571-3.503).Conclusion: This study revealed a significant relationship between positive familial history of acne and prevalence of acne vulgaris.
Edalatkhah Hassan; Khalilollahi S. Hojat; Sani Nayyereh Amini; Taher Athar
Volume 9, Issue 4 , 2006, , Pages 313-318
Abstract
Background and aim: Warts are the most common clinical presentation of human papilloma virus infection of human skin and mucosa. They are more common on hand, foot, face and genital area. They are benign skin colour lesions with different clinical forms. There is no specific treatment for them. In this ...
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Background and aim: Warts are the most common clinical presentation of human papilloma virus infection of human skin and mucosa. They are more common on hand, foot, face and genital area. They are benign skin colour lesions with different clinical forms. There is no specific treatment for them. In this trial the therapeutic effect of intralesional injection of bleomycin and cryotherapy on common warts of hands and feet was compared.Materials and Methods: Fifty-two subjects entered the study but 44 patients completed the trial. Warts were treated by intralesional injection of bleomycin 0.5 mg/ml or liquid nitrogen on symmetric aspects of both hands and feet. We used cryo-spray gun for application of liquid nitrogen. Treatment was repeated every 2 weeks for a maximum of three times. Treatment was done by a dermatologist and treatment response was evaluated by another dermatologist. Collected data were analyzed by SPSS software.Results: In this trial 23 female and 21 male patients were studied. Totally, 253 warts were treated by cryotherapy and 226 warts by intralesional bleomycin. Cure rate was 73.1% for cryotherapy and 87.6% for intralesional bleomycin (P<0.001).Conclusion: Cure rate for intralesional bleomycin was higher than cryotherapy. Intrelesional bleomycin therapy is an effective and safe treatment for common warts.
