SM Davoudi; P Rostami; SN Emadi; B Sadr; E Khabiri
Volume 9, Issue 3 , 2006, , Pages 217-220
Abstract
Background and aim: Paederus dermatitis is an acute self-healing blistering disease caused by an insect from the genus Paederus species. Although it is a self-limited disease, it can cause disablement and suffering. The objective of this study was to investigate the efficacy of fluocinolone cream, triclocarban(TCC) ...
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Background and aim: Paederus dermatitis is an acute self-healing blistering disease caused by an insect from the genus Paederus species. Although it is a self-limited disease, it can cause disablement and suffering. The objective of this study was to investigate the efficacy of fluocinolone cream, triclocarban(TCC) soap and betamethasone lotion in comparison with placebo in the treatment of paederus dermatitis.Materials and Methods: This study was a randomized single blind placebo controlled trial which was performed in Behshahr hospitals during a period of two months. Seventy-seven patients with paederus dermatitis were randomized to treatment with fluocinolone cream, TCC soap, betamethansone lotion or a placebo. The conditon of each patient was checked three times; i.e., on their first, fifth and twelfth day of receiving treatment. Finally, depending on their response to treatment, they were divided into two groups, those who fully recovered and those failing to recover.Results: Of the 77 patients studied, 18 were treated with a placebo, 17 with betamethasone lotion, 24 with fluocinolone cream and 17 with TCC soap. Complete recovery at the end of treatment was fluocinolone 100% , betamethasone 100%, TCC 58.8% and placebo 33.3%. Significant differences were observed between two first groups and the placebo group (P=0.0001) but no significant difference was observed between TCC soap and placebo.Conclusion: Topical corticosteroids displayed a relative and significant improvement in paederus dermatitis.
H Mortazavi; M Reziei; SN Emadi; MJ Nakhaei; MR Soroush; P Noor Mohammadpour; S Toosi
Volume 8, Issue 3 , 2005, , Pages 177-189
Abstract
Background: Mustard gas is a disabling chemical weapon and was widely used in first world war and Iraq-Iran war. Its toxic effects could be acute or chronic and they could particularly affects lungs, eyes and skin. Objective: To study the frequency of chronic complications of sulfure Mustard gas in Iranian ...
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Background: Mustard gas is a disabling chemical weapon and was widely used in first world war and Iraq-Iran war. Its toxic effects could be acute or chronic and they could particularly affects lungs, eyes and skin. Objective: To study the frequency of chronic complications of sulfure Mustard gas in Iranian victims 14 to 20 years after exposure. Patients and Methods: This descriptive cross-sectional study was performed on 800 patients that were randomly selected from different provinces of Iran, who had been exposed to sulfure Mustard gas during 1983 to 1988. These patients were clinically re-evaluated in 2002-03 and laboratory tests were performed if necessary. Results: The mean age of the patients at the time of study was 39.3 (±9.8) years. 3 types of skin lesions were observed. Non-specific lesions including 39.6% xerosis, 19% pigmentary disorders, 17.4% cherry angioma, 12.7% seborrheic dermatitis, 12.2% eczema (Dermatitis), 11.6% acneiform lesions, 7% tinea versicolor, 5.1% urticaria, 3.6% vitiligo, 2.5% alopecia areata, 2% psoriasis, and 1.3% aphthous stomatitis. Specific skin lesion called mustard scar was defined according to morphology, location, history and observed in 44 (5.5%) patients. Malignant neoplasms including basal cell carcinoma, Bowen’s disease, squamous cell carcinoma, mycosis fungoides and dermatofibrosarcoma protuberans occurred in 9 victims (1.1%). Conclusion: Mustard gas can cause acute and late-onset skin lesions. Specific lesion of Mustard gas called Mustard scar is the most important finding of this study.
M Barzegari; SN Emadi; RM Robati
Volume 8, Issue 3 , 2005, , Pages 237-241
Abstract
Congenital diffuse Melanosis is one of the rarest clinical manifestations of hereditary universal Melanosis and only few cases have been reported all over the world. The presented case is a 54-year-old man who presented to us complaining of erythematous annular lesions on his face and neck since 8 months ...
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Congenital diffuse Melanosis is one of the rarest clinical manifestations of hereditary universal Melanosis and only few cases have been reported all over the world. The presented case is a 54-year-old man who presented to us complaining of erythematous annular lesions on his face and neck since 8 months ago. Diffuse pigmentation of his skin took our attention. According to the patient, diffuse hyperpigmentation was present at birth and there was no obvious changes up to now. His mother and sister had similar hyperpigmentation. He had 2 sons with a similar hyperpigmentation, but his daughter had normal skin pigmentation. All laboratory investigation for the causes of hyperpigmentation were reported normal and investigation for causes of secondary hyperpigmentation did not reveal any abnormality. In histopathological assay, the erythematous lesion was reported to be discoid lupus erythematous and the diagnosis of hyperpigmented lesion reported as congenital diffuse Melanosis.
MJ Nazemi; SN Emadi; S Toosi
Volume 8, suppl , 2004, , Pages 5-10
Abstract
Cyclosporin and azathioprine are immunosuppressive drugs, used widely in kidney transplant patients. A significant association between immunosuppressive therapy and multiple warts was described several years ago. There are also some reports of sebaceous gland hyperplasia in kidney transplant patients ...
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Cyclosporin and azathioprine are immunosuppressive drugs, used widely in kidney transplant patients. A significant association between immunosuppressive therapy and multiple warts was described several years ago. There are also some reports of sebaceous gland hyperplasia in kidney transplant patients receiving cyclosporin. We report herein a 57-year-old woman who developed multiple warts on her hands and feet, lower lid syringomas, sebaceous gland hyperplasia of forehead and multiple mucosal irritation fibromas on tongue after kidney transplantation and a long course of treatment with oral cyclosporin, azathioprine and prednisolone since 6 years ago.
MJ Nakhaei; SN Emadi; S Toosi; Sh Khateri; B Rayegan
Volume 8, suppl , 2004, , Pages 26-30
Abstract
Sulfur mustard or mustard gas has been widely used as a chemical weapon in the first world war and Iraq-Iran war. It causes acute and chronic complications in lungs, eyes and skin. In skin, mustard is toxic, mutagenic, and carcinogenic via alkylation of cellular proteins in enzymes, cell membranes, cytoplasm ...
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Sulfur mustard or mustard gas has been widely used as a chemical weapon in the first world war and Iraq-Iran war. It causes acute and chronic complications in lungs, eyes and skin. In skin, mustard is toxic, mutagenic, and carcinogenic via alkylation of cellular proteins in enzymes, cell membranes, cytoplasm and particularly cell nucleus as well as in DNA components of the epidermis, dermis and skin appendages. Herein, we report a 37-year-old man who developed widespread blistering on his right thigh after sulfur mustard exposure in 1988. Now multiple cherry angiomas, decreased hair growth and pigmentary disorder are visible at the site of previous injury.
MJ Nazemi Tabrizi; AH Ehsani; SN Emadi; P Noormohammad Poor; P Mehrian
Volume 8, Issue 1 , 2004, , Pages 62-65
Abstract
Although lichen planus is a fairly common disorder, its familial occurrence is uncommon and varies between 1.5 and 10.7%. In most reports, only two or three members of the family have had disease but occasionally more family members may be affected. We present a case of lichen planus, whose father, mother, ...
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Although lichen planus is a fairly common disorder, its familial occurrence is uncommon and varies between 1.5 and 10.7%. In most reports, only two or three members of the family have had disease but occasionally more family members may be affected. We present a case of lichen planus, whose father, mother, and maternal aunt also had this disease.
H Mortazavi; SN Emadi; F Farnaghi; H Seirafi; F Safar
Volume 7, Issue 3 , 2004, , Pages 171-178
Abstract
Immunosuppression is known to be associated with increased rate of malignancies and widespread dermatophytosis in the patients with sezary syndrome and this may account for the occurrence of Kaposi’s sarcoma and generalized dermatophytosis in patients in this report. Herein, we report a 58-year-old ...
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Immunosuppression is known to be associated with increased rate of malignancies and widespread dermatophytosis in the patients with sezary syndrome and this may account for the occurrence of Kaposi’s sarcoma and generalized dermatophytosis in patients in this report. Herein, we report a 58-year-old farmer man, who admitted with two months history of severely pruritic skin lesions, which progressed to erythroderma. Concurrently some vascular lesions were observed on glans penis off the patient suggestive of Kaposi’s sarcoma. Leukocytosis with eosinophilia (20%) and atypical lymphocytosis (More than 10%) were present. Microscopic examination of biopsy of erythrodermic skin lesions on trunk revealed pautrier micro abscess with dermal lymphocytic infiltration and cellular atypia, and the peripheral blood sample showing sezary cells and high ratio of CD4/CD8 (45) lymphocyte were in favor of diagnosis of sezary syndrome. The pathologic evaluation of the vascular lesion of glans penis proved the diagnosis of Kaposi’s sarcoma. During the progression of disease, the patient was invaded by generalized dermatophyte infection. KOH smear of annular skin lesion showed mycelia of dermatophyte and culture proved trichophyton rubrum to be the pathogenic agent.