Maryam Nasimi; vahide Lajevardi; Hamidreza Mahmoudi; Fatemeh Arbab; Safoura Shakoei
Abstract
Background: Lichen planus (LP) is a chronic inflammatory disease of unknown etiology. There is conflicting data on the link between LP and metabolic syndrome. This study evaluated the association of chronic subtypes of LP, namely oral lichen planus and lichen planopilaris (LPP), with metabolic syndrome.Methods: ...
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Background: Lichen planus (LP) is a chronic inflammatory disease of unknown etiology. There is conflicting data on the link between LP and metabolic syndrome. This study evaluated the association of chronic subtypes of LP, namely oral lichen planus and lichen planopilaris (LPP), with metabolic syndrome.Methods: In this cross-sectional study, 66 patients with oral and follicular LP were evaluated for metabolic syndrome based on the US National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) criteria and were compared against 66 healthy controls. Waist circumference, body mass index (BMI), systolic and diastolic blood pressure, fasting blood sugar (FBS), and lipid profile were measured for each individual.Results: There was no significant difference in the prevalence of metabolic syndrome (13 [19.7%] vs. 8 [12.1%]; P = 0.23) and dyslipidemia (51 [77.3%] vs. 49 [74.2%]; P = 0.68) between the study groups. These findings remained statistically insignificant in both genders. The waist circumference (P = 0.008) and diastolic blood pressure (DBP) (P = 0.02) were significantly higher in the LP group than the healthy individuals. Our data showed that each unit increment in waist circumference and DBP leads to a 4.1% (P = 0.02) and 4.7% (P = 0.03) increase in the chance of LP,respectively.Conclusion: Patients with oral LP and LPP do not have a higher prevalence of metabolic syndrome or dyslipidemia than healthy individuals. However, they are more vulnerable to central obesity and high diastolic pressure, for which they should be routinely screened.
Ghazal Shariatpanahi; Rezvan Hashemi; Mahsa Asadabadi; Nava Shirzadi; Nazgol Sadat Haddadi; Safoura Shakoei
Abstract
Background: Acne is a common chronic inflammatory skin disease predominantly occurring during adolescence; this condition adversely affects a person’s self-esteem and can be associated with metabolic disorders. This study aimed to investigate the prevalence of metabolic syndrome and its components ...
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Background: Acne is a common chronic inflammatory skin disease predominantly occurring during adolescence; this condition adversely affects a person’s self-esteem and can be associated with metabolic disorders. This study aimed to investigate the prevalence of metabolic syndrome and its components in adolescent girls with acne compared to a control group. Materials and Methods: In this cross-sectional study,105 adolescent girls aged 12-18 years were assigned to either the acne (case; n=55) or control group (n=50). The case group was selected from the Dermatology Department of a general hospital in Tehran, Iran, between January and August 2017. Acne lesions were confirmed and graded by a dermatologist. Clinical and biochemical parameters were evaluated for all participants. Results: The prevalence of metabolic syndrome in patients with and without acne was 18.2% and 14%, respectively. As a result, metabolic syndrome was not correlated with acne in adolescent girls (P=0.561). In addition, the mean body mass index (P=0.89), waist circumference (P=0.62), mean systolic and diastolic blood pressures (P=0.57 and 0.62, respectively), fasting blood sugar (P=0.59), total cholesterol, and low-density lipoprotein cholesterol levels were comparable between the studied groups (P>0.05). Moreover, triglyceride levels were significantly lower in the acne group (P=0.028), whereas this group featured a higher level of high-density lipoprotein cholesterol (P=0.02). However, the logistic regression results showed that none of the measured lipids were associated with acne. Conclusion: The findings indicated that metabolic syndrome and its components (representing metabolic imbalance) were not correlated with acne in adolescent girls.
Safoura Shakoei; Nazanin Nasri; Ghazal Shariatpanahi; Rezvan Hashemi
Abstract
Background: Acne is a chronic inflammatory skin disease and a cosmetic problem with considerable emotional and psychological side effects and symptoms, such as pain and pruritus. Some controversies exist concerning the involvement of dietary factors, including glycemic load (GL), ...
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Background: Acne is a chronic inflammatory skin disease and a cosmetic problem with considerable emotional and psychological side effects and symptoms, such as pain and pruritus. Some controversies exist concerning the involvement of dietary factors, including glycemic load (GL), in the pathogenesis of acne. Accordingly, we aimed to determine the role of GL and anthropometric measures in acne development among girls aged 12-18 years in Tehran, Iran.Methods: In this cross-sectional study, 99 girls (45 girls without acne and 54 girls with acne) aged 12 18 years completed a threeday food record. Anthropometric measures, such as height, weight, waist circumference, and body mass index (BMI), were also assessed. Additionally, an expert dermatologist scored the severity of acne, and then, anthropometric measures and GL were examined in the groups.Results: The results showed no significant difference in dietary GL, height, weight, BMI, and waist circumference between the groups. Furthermore, the severity of acne was not significantly associated with GL.Conclusion: The present results did not confirm the association between acne and dietary carbohydrates, including GL. However, further research can contribute to determination of the effect of diet on acne and its severity.
