Farhad Handjani; Nasrin Saki; Sona Zandi; Mohammad Sadegh Sayyafan; Bahareh Kardeh; Yasaman Emami; Alireza Heiran
Volume 19, Issue 1 , 2016, , Pages 14-5
Abstract
Background: Wart is a common skin disease that can occur at any age. While they are usually benign and self-limited, they can become irritating and cosmetically disabling to patients. The objective of this study is to compare the effectiveness of a topical 85% formic acid preparation with a combination ...
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Background: Wart is a common skin disease that can occur at any age. While they are usually benign and self-limited, they can become irritating and cosmetically disabling to patients. The objective of this study is to compare the effectiveness of a topical 85% formic acid preparation with a combination of topical salicylic acid and lactic acid.Methods: We enrolled 66 patients, 7-60 years of age, in this triple-blind study. Patients were randomly divided into 2 groups: group 1 received a topical 85% formic acid solution and group 2 received DuoFilm (topical 16.7% salicylic acid + 16.7% lactic acid). The duration of treatment was a maximum of 4 weeks and we followed the patients every two weeks.Results: In group 1, 74.1% of the warts completely healed and 3.5% partially healed. In group 2 complete healing occurred in 40.8% and partial healing in 26.8% of the warts (P<0.001). Statistical analysis showed a significant difference in the favor of formic acid on the hands (P<0.001) but we did not observe a better effect for the feet. The time to complete healing was less for the majority of patients in the formic acid group (1 week versus 4 weeks). There were minimal adverse effects in each group, none that necessitated cessation of treatment.Conclusion: Topical formic acid had a higher cure rate for warts compared with a conventional preparation that consisted of both topical salicylic acid and lactic acid. This effect was particularly noted on the hands. This topical remedy could be regarded as an alternative to conventional treatments in the management of warts.
Farhad Handjani; Nasrin Saki; Bahareh Kardeh; Masoomeh Maghsoodi
Volume 16, Issue 1 , 2013, , Pages 6-8
Abstract
Background: Hirsutism is defined as the presence of terminalhairs with a male-like pattern in women, due to the increasedlevels of androgens or increased responses of the target organs toandrogens. Facial hirsutism has a negative effect on the quality oflife in female patients. Among the many therapeutic ...
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Background: Hirsutism is defined as the presence of terminalhairs with a male-like pattern in women, due to the increasedlevels of androgens or increased responses of the target organs toandrogens. Facial hirsutism has a negative effect on the quality oflife in female patients. Among the many therapeutic modalitiesfor hirsutism, laser therapy is of great acceptability. The longpulse Alexandrite laser, diode laser, and Nd:YAG laser are themost commonly used lasers in the treatment of hirsutism. In thisstudy, we assessed the effect of laser therapy on the quality oflife of the patients with hirsutism, using the Dermatology LifeQuality Index (DLQI) and Visual Analog Scale (VAS).Method: Forty-two female patients with idiopathic hirsutism,ranging from 18 to 34 years old, were studied during a courseof laser therapy lasting for at least 4 months for up to 3 courses.Each patient completed a DLQI and VAS questionnaire beforeand after treatment. The VAS questionnaire was also filled outby the dermatologist.Result: Following laser therapy, the average DLQI score,decreased by 10 points (a statistically significant difference withp- value<0.001). VAS also declined and there was a moderate togood correlation between the VAS scores given by the patientand the dermatologist.Conclusion: This study demonstrated that laser therapy improvedthe quality of life in patients with hirsutism.