Rezvan Talaee; Mahdiyeh Mohammadzadeh; Habibollah Rahimi
Abstract
Background: Cracked nipples represent the most common complication of breastfeeding. This study aimed to compare the therapeutic effect of the Cicalfate® commercial cream (containing copper, zinc, and sucralfate) with white soft paraffin in treating cracked nipples. Methods: This study was a double-blind ...
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Background: Cracked nipples represent the most common complication of breastfeeding. This study aimed to compare the therapeutic effect of the Cicalfate® commercial cream (containing copper, zinc, and sucralfate) with white soft paraffin in treating cracked nipples. Methods: This study was a double-blind clinical trial conducted on 115 patients with cracked nipples. Patients were randomly divided into two case and control groups. The case group received the Cicalfate® cream and the control group received white soft paraffin. After a period of one to two weeks of treatment, all patients were re-examined and the severity and rate of their recovery were recorded. Data were analyzed using SPSS version 15. Results: In this study, 68 patients were in the case group and 47 were in the control group. The comparison of the two groups in terms of improvement of the right nipple with the removal of other variables showed that the degree of cracking reduction in the case group was 3.3 times that of the control group (OR=3.3; CI=1.3-8.3). Also, the comparison of the two groups in terms of improvement of the left nipple with removing the effect of other variables showed that the degree of cracking reduction in the case group was 5.3 times that of the control group (OR=5.3; CI=2.0-14.1). Conclusion: The results of this study showed that the therapeutic effect of Cicalfate® is more than that of white soft paraffin.
Rezvan Talaee; Batoul Zamani; Hasan Ehterami
Volume 11, Issue 4 , 2008, , Pages 177-178
Abstract
A 7 – year - old Caucasian girl presented with a 3-month history of nodules on her thighs and buttocks. During a one-month period, the lesions gradually increased in size and number. They became indurate and tender. Similar nodules appeared on forearms after 4 months. The lesions gradually healed ...
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A 7 – year - old Caucasian girl presented with a 3-month history of nodules on her thighs and buttocks. During a one-month period, the lesions gradually increased in size and number. They became indurate and tender. Similar nodules appeared on forearms after 4 months. The lesions gradually healed with a depressed scar. On physical examination, we found many indurate areas 10-40 mm in diameter .The surface of some of them was erythematous and scaly. The lesions were not ulcerated and did not have a discharge (figure 1). On examination, she was afebrile and healthy, organs such as heart, lungs, abdomen , joints and muscles were normal. Laboratory evaluation findings including complete blood cell count, liver and renal function test values, ESR, CRP,VDRL, BUN, Creatinin, complement were all normal .The titers for FANA, Anti ds DNA, Anti Sm, Anti Scl-70, Anti –RNP, Anti-Ro, Anti-La, Anti –Jo1, Anti Phospholipid Ab, Anti cardiolipin Ab, c- ANCA , p- ANCA were negative. A skin biopsy was taken (figures 2).
