Alireza Heiran; Farhad Handjani; Nasrin Saki; Maryam Rezaee
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic and possesses a tropism for multiple organs.
In this systematic review, we put together all relevant papers to assess the link between COVID-19 infection and acral ...
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic and possesses a tropism for multiple organs.
In this systematic review, we put together all relevant papers to assess the link between COVID-19 infection and acral lesions (particularly chilblain-like lesions) and to determine whether these lesions can be put together in a spectrum of manifestations.
Skin manifestations of COVID-19 vary, ranging from mostly acral chilblain-like, livedoid lesions or ischemia and necrosis to vesicular eruptions, maculopapular lesions, urticaria, oral or periorbital lesions, and drug eruptions.
A great deal of scientific evidence have focused on the peculiar erythematous and purpuric violaceous acral
lesions in young and healthy individuals resembling chilblains (pernio), leading the scientific community to investigate the association between these lesions and SARS-CoV-2. Furthermore, this is suggestive that some COVID-19 skin manifestations like livedo reticularis and acral ischemia and necrosis might share
dermatopathologic features with thrombophilic states.
Farhad Handjani; Nasrin Saki; Sona Zandi; Mohammad Sadegh Sayyafan; Bahareh Kardeh; Yasaman Emami; Alireza Heiran
Volume 19, Issue 1 , 2016, , Pages 14-5
Abstract
Background: Wart is a common skin disease that can occur at any age. While they are usually benign and self-limited, they can become irritating and cosmetically disabling to patients. The objective of this study is to compare the effectiveness of a topical 85% formic acid preparation with a combination ...
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Background: Wart is a common skin disease that can occur at any age. While they are usually benign and self-limited, they can become irritating and cosmetically disabling to patients. The objective of this study is to compare the effectiveness of a topical 85% formic acid preparation with a combination of topical salicylic acid and lactic acid.Methods: We enrolled 66 patients, 7-60 years of age, in this triple-blind study. Patients were randomly divided into 2 groups: group 1 received a topical 85% formic acid solution and group 2 received DuoFilm (topical 16.7% salicylic acid + 16.7% lactic acid). The duration of treatment was a maximum of 4 weeks and we followed the patients every two weeks.Results: In group 1, 74.1% of the warts completely healed and 3.5% partially healed. In group 2 complete healing occurred in 40.8% and partial healing in 26.8% of the warts (P<0.001). Statistical analysis showed a significant difference in the favor of formic acid on the hands (P<0.001) but we did not observe a better effect for the feet. The time to complete healing was less for the majority of patients in the formic acid group (1 week versus 4 weeks). There were minimal adverse effects in each group, none that necessitated cessation of treatment.Conclusion: Topical formic acid had a higher cure rate for warts compared with a conventional preparation that consisted of both topical salicylic acid and lactic acid. This effect was particularly noted on the hands. This topical remedy could be regarded as an alternative to conventional treatments in the management of warts.
Farideh Jowkar; Najmeh Radgoodarz; Nasrin Saki; Alireza Heiran
Volume 19, Issue 1 , 2016, , Pages 11-15
Abstract
Background: Laser treatment is a rapid, non-invasive procedure for long-term hair removal. Lasers operate based on the principle of selective photothermolysis and target melanin in the hair follicle. We intend to determine the level of hirsute patient satisfaction with the alexandrite laser hair removal ...
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Background: Laser treatment is a rapid, non-invasive procedure for long-term hair removal. Lasers operate based on the principle of selective photothermolysis and target melanin in the hair follicle. We intend to determine the level of hirsute patient satisfaction with the alexandrite laser hair removal procedure.Methods: In this cross-sectional study 82 hirsute patients with unwanted hair on their faces were enrolled. The patients received treatment with a 755 nm alexandrite laser (GentleLASE, Candela Corporation, USA). We documented their level of satisfaction with this laser in terms of hair removal. Laser therapy, electrolysis, and depilation were compared.Results: Patients ≥30 years old expressed greater satisfaction compared to those <30 years of age (P=0.03). Patients with medically related hirsutism had the same satisfaction as the idiopathic hirsute group (P=0.81). Patients rated laser hair removal as 4.12 compared to depilation and 3.96 compared to electrolysis. From total patients, 60.97% would recommend laser treatment to other hirsute patients. There were 79.3% of patients who expressed satisfaction with alexandrite laser hair removal.Conclusions: Most patients expressed satisfaction with the alexandrite laser hair removal procedure. Age played a significant role in patient satisfaction.