Mohammad Radmanesh; Nasibeh Sohrabian; Ramin Radmanesh
Volume 16, Issue 4 , 2013, , Pages 159-161
Abstract
The patients with universal vitiligo and residual pigmented patches usually do not benefit from available repigmenting methods and are better scheduled for depigmentation by medical, laser,and or freezing procedures. A 37-year-old lady with universal vitiligo and remaining pigmentation ...
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The patients with universal vitiligo and residual pigmented patches usually do not benefit from available repigmenting methods and are better scheduled for depigmentation by medical, laser,and or freezing procedures. A 37-year-old lady with universal vitiligo and remaining pigmentation in the left anterior chest wall, both ventral forearms, and diffuse mottled depigmentation of the face was scheduled for facial depigmentation by 532 nm Q-switched Nd-YAG laser. All residual pigmented facial areas were treated uniformly. Two months after laser therapy, we paradoxically observed considerable repigmentation of the treated areas with only some remaining scattered and round depigmented patches. Through an unknown mechanism, a true reverse Koebner phenomenon with its resultant repigmentation rather than depigmentation was observed in our patient.
Mohammad Radmanesh; Ramin Radmanesh
Volume 16, Issue 1 , 2013, , Pages 17-20
Abstract
Background: Although cryotherapy has been reported as atechnique for depigmenting residual pigmented patches inpatients with universal vitiligo, Q-switched Nd-YAG lasershave not yet been used for this purpose. The aim of this studywas to compare the efficacy of cryotherapy with that of 532nmQ-switched ...
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Background: Although cryotherapy has been reported as atechnique for depigmenting residual pigmented patches inpatients with universal vitiligo, Q-switched Nd-YAG lasershave not yet been used for this purpose. The aim of this studywas to compare the efficacy of cryotherapy with that of 532nmQ-switched Nd-YAG laser therapy for depigmentation in patientswith universal vitiligo.Method: Six adult patients (4 male and 2 female) with universalvitiligo and facial residual pigmented patches were treatedsimultaneously with cryotherapy on the right and the frequencydoubled532nm Q-switched Nd-YAG laser therapy on the leftside. The laser parameters used were spot size 3-5mm, frequencyrate 10 hertz, and the fluence was 5J/cm2. The cryo system wasa closed contact CO2 Cryo gun. The patients were scheduled tobe treated monthly.Result: The depigmentation was complete after three successivesessions of cryotherapy and 30-45 days after the last session, incomparison with simultaneous 30-70% depigmentation of the laserside. No scar or permanent sequellae developed on either side.Conclusion: Cryotherapy is more effective and fast-actingthan Q-switched Nd-YAG laser for depigmentation of residualpigmented patches in patients with universal vitiligo.