Mokhtari Fatemeh; Gholami Maryam; Mozafarpoor Samaneh
Volume 20, Issue 3 , 2017, , Pages 93-96
Abstract
Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of ...
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Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of genital Crohn’s disease (CD) is in the form of erythema and edema of the labia and scrotum. Here, we have reported the rare case of a patient with late-onset genital CCD. The patient was a 61-year-old woman with a history of chemotherapy for breast cancer. She presented with genital, intergluteal, and perianal ulcers without any fistula, sinus or scars, which was treated as an unusual presentation of CD. The patient has not had any intestinal manifestation during three years of follow-up.
Ebrahimzadeh Mohammad; Dehghani Farideh; Amirniroumand Niloofar
Volume 17, Issue 4 , 2014, , Pages 130-133
Abstract
Background: Lichen planus is a chronic inflammatory disease ofunknown etiology that may involve mucocutaneous tissues. Themain aim of our study was to evaluate the frequency of oral andgenital lichen planus in men and women affected by skin lesions.Method: A total of 132 patients with clinical and histopathologicaldiagnosis ...
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Background: Lichen planus is a chronic inflammatory disease ofunknown etiology that may involve mucocutaneous tissues. Themain aim of our study was to evaluate the frequency of oral andgenital lichen planus in men and women affected by skin lesions.Method: A total of 132 patients with clinical and histopathologicaldiagnosis of lichen planus were evaluated for oral and genitalinvolvement. All data was analyzed by SPSS version 19. Chisquare test and t-test were used for statistical analysis.Result: Of 132 patients enrolled in this study, 72 were men and60 were women. Genital and oral lichen planus
Maryam Akhyani; Cheyda Chams-Davatchi; Zahra Safai Naraghi; Maryam Daneshpazhooh; Siavash Toosi; Masoud Asgari; Fatemeh Malek Hami
Volume 10, Issue 3 , 2007, , Pages 194-202
Abstract
Background and aim: Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim ...
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Background and aim: Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim was to evaluate involvement of the female genital tract and cervicovaginal Papanicolaou (Pap) smears in PV.Materials and methods: The study included 77 patients with PV visited from April 2005 to February 2007. Each patient was subjected to gynecological examination and cervicovaginal Pap smear.Results: The mean age of patients was 44.7±13 years. Genital lesions were observed in 39 patients (50.6%). Labia minor was involved in 36 patients (92.3%), while labia major in 11 (28.2%), vagina in 14 (35.8%), and cervix in six (15.3%). Cervicovaginal smears of 20 patients (25.9%) showed PV. Among 72 satisfactory smears, cervical Pap smears were normal in 25 patients (34.7%), inflammatory in 43 patients (59.7%), and dysplastic (low-grade cervical intra-epithelial neoplasia [CIN I]) in four patients (5.5%). In 2 of these patients, Pap smears was normal repeated when patients were in remission.Conclusion: Involvement of the female genital tract might not be as infrequent as was previously thought and it is probably the second most common mucosal site of PV after oral mucosa. Genital lesions may be missed and the need for thorough pelvic examination should not be overlooked.