Nahidi Yalda; Javidi Zari; Shakeri Mohammad Taghi; Farrokhnezhad Somayyeh
Volume 15, Issue 3 , 2012, , Pages 80-84
Abstract
Introduction: Acne is a common problem in adolescent and youngage groups, for which several risk factors have been suggested.One of the risk factors is smoking. In studies on the relationshipbetween smoking and acne, conflicting results have been obtained.Method: This study was conducted on 133 male ...
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Introduction: Acne is a common problem in adolescent and youngage groups, for which several risk factors have been suggested.One of the risk factors is smoking. In studies on the relationshipbetween smoking and acne, conflicting results have been obtained.Method: This study was conducted on 133 male patients whowere visited at the dermatology clinic of Imam Reza hospital dueto acne as the case group, and 133 healthy individuals withoutany skin diseases including acne among those accompanying thepatients as the control group. The case and the control groups wereage matched. For each patient who had the criteria for inclusionin the study, a questionnaire was completed and the necessaryinformation was collected and then analyzed statistically.Result: The questionnaires were filled for 133 patients with acneand 133 healthy controls. Twenty-nine patients with acne (21.8%)and 12 patients in the control group (9.1%) were smokers, and thedifference between them was significant (P = 0.004). The numberof cigarettes smoked per day was significantly different in thetwo groups (4.75 in the case group versus 1.88 in the controlgroup). No correlation was found between smoking and acnelocalization, severity of acne, the type of lesion, symptomaticor asymptomatic nature of acne and acne complications. In thecase group, the smokers developed acne at an older age thanthe non-smokers.Conclusion: Patients with acne were more likely to smoke thanpatients without acne; thus, smoking might be a factor affectingthe incidence of acne.
F Pezeshk Pour; MJ Yazdan Panah; AR Taheri; H Assadi
Volume 6, Issue 4 , 2003, , Pages 28-30
Abstract
Background: Vitiligo is a common autoimmune skin disease that may occur in association with other autoimmune disorders especially those of the endocrine system. Diabetes mellitus is a common endocrine disease associated with vitiligo. Objective: To study the association of vitiligo and diabetes mellitus. ...
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Background: Vitiligo is a common autoimmune skin disease that may occur in association with other autoimmune disorders especially those of the endocrine system. Diabetes mellitus is a common endocrine disease associated with vitiligo. Objective: To study the association of vitiligo and diabetes mellitus. Patients and Methods: In this descriptive cross-sectional study, 750 diabetic patients referred to Mashhad Diabetes Center were studied in Shahrivar 1380. Results: Thirty-two (4.3%) of these patients suffered from vitiligo that mostly was of generalized type. The face was the most common site of involvement. Twenty-two patients (68.7%) were female and 10 patients (31.3%) were male. Five percent of female and 3.3% of male diabetics suffered from vitiligo. 4.2% of NIDDM diabetics and 4.7% of IDDM diabetics suffered from vitiligo. Conclusion: Vitiligo was more common in NIDDM than IDDM because of the higher prevalence of NIDDM, but the association of vitiligo with IDDM was stronger. Vitiligo was more common in female than male diabetics.
H Pourmoghim; Gh.H Ghaffarpour; J Malboobi
Volume 6, Issue 3 , 2003, , Pages 4-7
Abstract
Background: The strong association of Behcet’s disease with HLA-B5 antigen has been observed in several ethnic groups from Middle East to Far East. Objective: To evaluate the frequency and association of HLA-B5 and also likelihood ratio of involvement in Behcet’s disease in a group of Iranian ...
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Background: The strong association of Behcet’s disease with HLA-B5 antigen has been observed in several ethnic groups from Middle East to Far East. Objective: To evaluate the frequency and association of HLA-B5 and also likelihood ratio of involvement in Behcet’s disease in a group of Iranian patients. Patients and Methods: HLA-B5 antigen typing was performed by serologic method in 56 patients with Behcet’s disease (Diagnosed by International Study Group Criteria) and 71 cases with seronegative diseases as control group. The difference in frequency and association between HLA-B5 antigen and Behcet’s disease was evaluated by chi-square test and phi-test. Results: The phenotype frequencies of HLA-B5 antigen in Behcet’s disease patients and control group were 66% and 26% respectively (X=19.62, P=0.0001). The association of HLA-B5 antigen phenotype with Behcet’s disease was strong (Phi=0.39, P=0.0001). The likelihood ratio was 20:1 for HLA-B5 antigen positivity and Behcet’s disease. Gene frequency of HLA-B5 was 46% in Behcet’s disease patients and 14% in control group. Conclusion: This study revealed a strong association of HLA-B5 antigen with Behcet’s disease in Iranian patients.
