Fahimeh Abdollahimajd; Reem Diab; Hamideh Moravvej; Ayda Bahmanjahromi; Sahar Dadkhahfar; Azadeh Goodarzi; Afsaneh Sadeghzadeh Bazargan; Sayyed Mojtaba Nekooghadam; Mohammad Nikvar; Mohammad Shahidi Dadras
Abstract
Background: Cutaneous manifestations of coronavirus disease 2019 (COVID-19) are not uncommon and can be the presenting sign of the disease. We aimed to investigate the cutaneous manifestations in COVID-19 patients.Methods: This cross-sectional study was performed on COVID-19 patients referred to Shohada-e ...
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Background: Cutaneous manifestations of coronavirus disease 2019 (COVID-19) are not uncommon and can be the presenting sign of the disease. We aimed to investigate the cutaneous manifestations in COVID-19 patients.Methods: This cross-sectional study was performed on COVID-19 patients referred to Shohada-e Tajrish and Modarres hospitals, Tehran, Iran, from January 1, 2021 to March 31, 2021. Patients with cutaneous lesions were included in the study; if needed, patients were visited in person, and a biopsy was taken.Results: Of the 100 COVID-19 patients in this study, with a mean age of 45.53 ± 17.75 years, 37 (37%) were males. The most common cutaneous manifestation was urticaria (21%), followed by maculopapular eruptions (17%), petechiae/purpura (15%), pityriasis rosea-like lesions (15%), erythema multiforme (7%), pernio (6%), Vesicles/pseudovesicles/bullae (5%), and others (24%). Most lesions were erythematosus (87.63%). Legs (40%) were most frequently involved. The most common accompanying symptom was pruritus (52%), followed by burning sensations (18%) and pain (7%). Six patients had mucosal lesions; these lesions were the only mucocutaneous manifestations in three of them. Skin biopsies were taken from 11 patients, revealing epidermal changesin 10 (90.9%), dermal changes in 7 (63.6%), mucin deposition in 1 (9.1%), perivascular lymphocyte infiltration in 10 (90.9%), and neutrophil infiltration in 1 (9.1%).Conclusion: The frequency of skin manifestations was relatively high in this study, with urticaria as the most common cutaneous presentation of COVID-19. Special attention must be paid to the cutaneous lesions of COVID-19.
Shahrokh Mehrpisheh; Azadeh Memarian
Abstract
Background: Skin disorders in neonates can be considered as determining concepts for prognosis and genetic counseling. So far, few studies have investigated the relative frequency of neonatal skin disorders. The present study aimed to investigate cutaneous lesions and their relationship with other variables ...
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Background: Skin disorders in neonates can be considered as determining concepts for prognosis and genetic counseling. So far, few studies have investigated the relative frequency of neonatal skin disorders. The present study aimed to investigate cutaneous lesions and their relationship with other variables in neonates hospitalized in the neonatal intensive care unit (NICU).Methods: This cross-sectional study was conducted on 403 neonates hospitalized in the NICU of Rasoul Akram Hospital in 2014. After selecting the patients via convenience sampling, data were collected from the medical records.Results: Of the 403 neonates, 366 (90.8%) had no cutaneous lesions, while 37 (9.2%) had cutaneous lesions. Among the latter group, 18 (48.6%) cases were pathological. According to the results obtained, the gender, type of delivery, gestational age, and reason for hospitalization were not related to the presence of cutaneous lesions and their pathological status (P > 0.05). Moreover, gender, gestational age, and reasons for hospitalization had no significant relationship with the lesion type (P > 0.05). The type of delivery had a statistically significant association with the kind of cutaneous lesions (P = 0.043).Conclusion: Cutaneous lesions in neonates hospitalized in the NICU were less frequent in the present study compared to those in other studies, which can be attributed to the retrospective nature and the lack of direct medical examination of patients.
Mohammadreza Ghassemi; Abbas Zamanian; Gholamhossein Ghaffarpour; Nasrin Shayanfar; Shiva Ghods; Azadeh Goodarzi
Abstract
Heterotopic ossification is the formation of bone tissue at an abnormal site. The ossification of soft tissue outside the skeletal system can occur anywhere and can be found in mucosal tissues. This is the first case report of an osteoma mucosalis affecting the nail bed. We also reviewed the heterotopic ...
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Heterotopic ossification is the formation of bone tissue at an abnormal site. The ossification of soft tissue outside the skeletal system can occur anywhere and can be found in mucosal tissues. This is the first case report of an osteoma mucosalis affecting the nail bed. We also reviewed the heterotopic ossification and calcification of cutaneous and mucosal sites in the PubMed, Scopus, and Google Scholar databases.
Beuy Joob; Viroj Wiwanitkit
Mokhtari Fatemeh; Gholami Maryam; Mozafarpoor Samaneh
Volume 20, Issue 3 , 2017, , Pages 93-96
Abstract
Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of ...
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Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of genital Crohn’s disease (CD) is in the form of erythema and edema of the labia and scrotum. Here, we have reported the rare case of a patient with late-onset genital CCD. The patient was a 61-year-old woman with a history of chemotherapy for breast cancer. She presented with genital, intergluteal, and perianal ulcers without any fistula, sinus or scars, which was treated as an unusual presentation of CD. The patient has not had any intestinal manifestation during three years of follow-up.
Zahedi Mohammad Javad; Fekri Alireza; Rezazadeh Azadeh; Moosazadeh Mahmood; Karvar Mehran
Volume 18, Issue 4 , 2015, , Pages 174-178
Abstract
This case report describes a patient with cutaneous signs in the genital and peri-anal region suspicious of Crohn’s disease without any intestinal symptom or sign. Inflammatory bowel disease can be associated with some cutaneous signs. However, in this paper, we report a patient with isolated cutaneous ...
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This case report describes a patient with cutaneous signs in the genital and peri-anal region suspicious of Crohn’s disease without any intestinal symptom or sign. Inflammatory bowel disease can be associated with some cutaneous signs. However, in this paper, we report a patient with isolated cutaneous Crohn’s disease which is very rare (less than 100 case reports across the world). Our patient presented with inflammatory indurated plaques and sinuses in the genital region since 3 years ago. Colonoscopy showed no findings related to Crohn’s disease in the ascending, sigmoid, and descending colon, particularly the terminal ileum. The patient`s symptoms were relieved following treatment with infliximab. To the best of our knowledge, this is the first report of isolated cutaneous Crohn’s disease in Iran.