Nasim Niknezhad; Behnaz Hamedani; Abbas Zamanian; Reza Mahmoud Robati; Elnaz Hamedani
Abstract
Introduction: Acne vulgaris affects individuals of all ages, and isotretinoin is the most effective treatment available for this disease. However, serious adverse effects, including the possibility of depression and suicide, could limit its use. This study aimed to investigate the ...
Read More
Introduction: Acne vulgaris affects individuals of all ages, and isotretinoin is the most effective treatment available for this disease. However, serious adverse effects, including the possibility of depression and suicide, could limit its use. This study aimed to investigate the frequency of depression in patients with acne vulgaris treated with oral isotretinoin.Materials and Methods: Forty acne vulgaris patients treated with oral isotretinoin and 40 age- and sex-matched controls treated with a systemic antibiotic (doxycycline 100-200 mg/day) and atopical retinoid were enrolled in this study. The depression score was measured based on Beck’s Depression Inventory (BDI) in both groups before and after two months of treatment.Result: The BDI score and the rate of depression were not significantly different between the two groups after the twomonth treatment period. Moreover, we did not find any significant change in BDI score in each group after treatment (P > 0.05).Conclusion: Our study showed that short-course oral isotretinoin therapy does not increase the depression rate among acne vulgaris patients. It should be noted that oral isotretinoin causesa significant clinical improvement in patients with moderate to severe acne vulgaris, which could be associated with a decrease in depression scores.
Mahsa Ghajarzadeh; Maryam Ghiasi; Shahrbanoo Kheirkhah
Volume 14, Issue 4 , 2011, , Pages 140-143
Abstract
Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. ...
Read More
Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. Objectives: To evaluate depression and quality of life in Iranian patients with Alopecia areata . Methods: From January 2009 until January 2010 one hundred alopecia areata patients who were randomly selected (through simple random selection) from the outpatient clinic of Razi Hospital were asked to answer valid and reliable instruments such as Beck Depression Inventory (BDI), SF-36 and DLQI (Dermatology Life Quality Index) questionnaires. Results: The mean scores of BDI, SF-36and DLQI of the patients were 14.4±9.7, 68.04 ±15.1 and 6.4±5.5, respectively. The BDI score was significantly different between male and female participants (F=18.1 ±11.2 vs. M=12.7±8.5, p=0.01) but SF -36 and DLQI scores did not significantly differ between the two gender groups. Duration of the disease, BDI and age had no significant correlation with DLQI scores. Patients with extensive beard involvement had the highest BDI score and the lowest SF-36 score. Conclusion: mood disorders should be considered in Alopecia areata patients to address the risk of markedly impaired quality of life
I Esfandiar Pour; P Afshar Zadeh
Volume 6, Issue 3 , 2003, , Pages 13-18
Abstract
Background: Some skin diseases cause severe stress in patients and relieving these stresses greatly helps to treat the underlying disease and to prevent the recrudescence of it. Objectives: To determine the frequency of depression in patients suffering from vitiligo. Patients and Methods: 120 patients ...
Read More
Background: Some skin diseases cause severe stress in patients and relieving these stresses greatly helps to treat the underlying disease and to prevent the recrudescence of it. Objectives: To determine the frequency of depression in patients suffering from vitiligo. Patients and Methods: 120 patients with a clinical diagnosis of vitiligo referred to dermatologic clinics in Kerman from 1380 to 1381 were studied. The impression of vitiligo was made according to clinical interview and physical examination. After filling the questionnaire the patients were referred to psychiatric clinic to fill in the Hamilton questionnaire. Results: 120 patients included 74 women (61.6%) and 46 men (38.4%) with mean age of 23±13 years. 30.83% (37 patients) had no depressive disorder, 38.34% (46 patients) had depressed mood and 30.83% (37 patients) had major depressive disorder. From 37 patients with major depressive disorder, 27 patients (73%) were female and 10 patients (27%) were male (P<0.001). Conclusion: Any clinical intervention that reduces the extension and visibility of depigmentation will have psychologic benefit. It may be important to recognize and deal with the social and psychologic consequences of the disease.
Sh Enshaieh; A Kiani; A Yazdani
Volume 6, Issue 3 , 2003, , Pages 19-23
Abstract
Background: It seems that psychological factors have important role in beginning or exacerbation of psoriasis. On the other hand, psoriasis negatively impacts quality of lives of the patients. Objective: To determine the frequency of depression and anxiety disorders in psoriatic patients. Patients and ...
Read More
Background: It seems that psychological factors have important role in beginning or exacerbation of psoriasis. On the other hand, psoriasis negatively impacts quality of lives of the patients. Objective: To determine the frequency of depression and anxiety disorders in psoriatic patients. Patients and Methods: In this descriptive study we evaluated 83 psoriatic patients referred to dermatologic clinics in Isfahan from 1379 to 1380. Beck and zoonge questionnaires were completed by the patients to evaluate depression and anxiety, respectively. Analysis of data was done by SPSS program with 95% confidence interval. Results: The frequency of depression in the patients was 69.9%. The most common type of depression was “Relative depression” (26.5%). The frequency of anxiety in psoriatic patients was 20.5%. These figures are higher than that reported in general population in Isfahan. Conclusion: The frequencies of depression and anxiety disorders in psoriatic patients were higher than general population. There was a direct correlation between the duration of disease and the prevalence of depression and anxiety disorders.
