Maryam Zahed; Ladan Dastgheib; Maryam Sadat Sadati; Asma Soukhakian
Abstract
Background: Pemphigus vulgaris (PV) is a life-threatening autoimmune disease that affects the skin and mucosa. In most regions, little data is available on its epidemiology. This study aimed to present an overview of the worldwide epidemiology of pemphigus and evaluate the epidemiological features of ...
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Background: Pemphigus vulgaris (PV) is a life-threatening autoimmune disease that affects the skin and mucosa. In most regions, little data is available on its epidemiology. This study aimed to present an overview of the worldwide epidemiology of pemphigus and evaluate the epidemiological features of PV in the southwest of Iran.Methods: In this study, data including sex, age, time of disease onset, phenotype of the disease, geographic location of birth, geographic location of residence, level of education, and occupation of PV patients from 2004 to 2019 were collected from the records existing in the Oral Medicine Department of Shiraz Dental School and Shahid Faghihi Hospital, Shiraz, Iran.Results: In total, 249 PV patients with a mean age of 42.72 ± 13.3 years were included. The female to male ratio was 1.74:1. The annual incidence of PV in Fars province was 2.7 per million people. In this region, the most frequent phenotype was the mucocutaneous phenotype in 204 patients (81.9%), followed by the mucosal dominant phenotype in 40 (16.1%) and the cutaneous phenotype in 5 (2%). Regarding the level of education, 43.4% had less than a high school diploma, 24.9% had a high school diploma, 17.3% had an associate diploma or higher, and 14.5 % were illiterate. Moreover, 55.8% were housewives, 21.7% were self-employed, 19.3 % were employed, and 3.2% were jobless.Conclusion: The findings indicate that PV is a rare disease in the southwest of Iran compared with other regions. According to previous studies in this region, the incidence has decreased since 2005.
Dehghani Leila; Khanjani Narges; Bahrampour Abbas
Volume 15, Issue 4 , 2012, , Pages 111-116
Abstract
Background: Skin cancers are the most common human cancers.The most common skin cancers are basal cell carcinoma, squamouscell carcinoma and malignant melanoma. Different factors areinvolved in development of skin cancers; the most notable oneis exposure to ultraviolet radiation. In this study, the incidenceof ...
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Background: Skin cancers are the most common human cancers.The most common skin cancers are basal cell carcinoma, squamouscell carcinoma and malignant melanoma. Different factors areinvolved in development of skin cancers; the most notable oneis exposure to ultraviolet radiation. In this study, the incidenceof skin cancer was determined in Kerman province where islocated in the desert region of Iran with ample sunlight, duringa 5–year period.Method: All registered cases of skin cancers between March2005 and March 2010 were retrieved from the Kerman ProvinceCancer Registry. For each patient, data about age, gender,location, pathologic type of cancer and site of skin involvement,were obtained. Incidence rates according to the age, sex and thelocation of the lesions were calculated. Trend analysis was donefor the next 10 years.Result: During these 5 years, 1250 cases of skin cancer wererecorded. The incidence in men was 1.2 times higher than women.The highest incidence was seen in individulas older than 80 yearsof age. Fifty percent of all skin cancers were located on the face.The highest incidence was observed in the city of Kerman withan annual incidence of 12.6 in 100,000. Trend analysis showedthat the incidence of skin cancer in Kerman province would reach23 in 100 000 people in 2019, which is 2.3 times higher than theincidence rate in 2009.Conclusion: Skin cancer is a public health concern in Kermanprovince in Iran. Considering the desert climate and the intensity ofsunlight in most seasons, it is necessary to plan scientific practicalinterventions to prevent skin cancer and reduce its incidence..
Fariba Iraji; Nader Arbaby; Ali Asilian; Amir Hossein Siadat; Jalal Keshavarz
Volume 9, Issue 4 , 2006, , Pages 331-134
Abstract
Background and aim: Non-melanoma skin cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, ...
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Background and aim: Non-melanoma skin cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers. The objective of this study was to determine NMSC in Isfahan.Materials and Methods: We used data of the cancer resistery center for performing this study and the incidence of NMSC per 100,000 papulation was determined.Results: Overall 1681 cases were registered. The incidence of NMSC was calculated to be 10.67/100,000 population. The most common site for BCC and SCC was middle face.Conclusion: NMSC incidence in Isfahan is lower than west countries although this incidence is 10.67/100,000 in a year. It means that 5-6 thousand cases of NMSC occur in Iran each year. We can prevent its morbidity and mortality by early correct diagnosis.
L Dastgheib; P Peyravi
Volume 5, Issue 2 , 2002, , Pages 22-27
Abstract
Background: Pruritic dermatoses of pregnancy are important and common dermatoses during pregnancy. Objective: The purpose of this study was to determine the incidence and specificity or non-specificity of pruritic dermatoses of pregnancy and their effects on health of mother and fetus, during a period ...
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Background: Pruritic dermatoses of pregnancy are important and common dermatoses during pregnancy. Objective: The purpose of this study was to determine the incidence and specificity or non-specificity of pruritic dermatoses of pregnancy and their effects on health of mother and fetus, during a period of one year. Patients and Methods: The data were gathered by questionnaires completed by midwives in two antenatal clinics in Shiraz from October 1999 to October 2000. The pregnant patients with pruritic dermatoses were referred to dermatology outpatient clinic and evaluated according to their history, physical examination and laboratory workups. Results: Twenty-five patients out of 9500 pregnant women had pruritic lesions, so the incidence rate was 0.26%. Pruritic urticarial papules and plaques of pregnancy and eczema were the most common dermatoses. One mortality and two morbidities in neonates of these mothers were observed. Conclusion: Because dermatoses of pregnancy are common and important diseases which can affect the health of both mother and fetus, further research in this field is necessary.
