Ramin Radmanesh; Mohammad Radmanesh
Abstract
Background: There is no cure for xeroderma pigmentosum (XP) patients who suffer from persistent freckling and recurrent lifethreatening malignancies. We aimed to remove facial lentiginous pigmentations using CO2 laser resurfacing.Methods: 5 patients with clinically proven XP living in their third decade ...
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Background: There is no cure for xeroderma pigmentosum (XP) patients who suffer from persistent freckling and recurrent lifethreatening malignancies. We aimed to remove facial lentiginous pigmentations using CO2 laser resurfacing.Methods: 5 patients with clinically proven XP living in their third decade were scheduled to be treated with CO2 laser resurfacing. After tumescent anesthesia, the whole facial skin was treated with 3 UltraPulse® conventional CO2 ablation passes. The parameters used were 6 mJ, 5 mJ, and 4 mJ for the first to third passes. The mandibular areas were treated with two passes of 4 and 3.2 mJ, while the eye contours were treated with two passes of 3.6 mJ and 3.2 mJ.Results: The face was edematous and almost free of freckling immediately after resurfacing. The edema persisted for a week. The facial skin oozed within the first three days, followed by crust formation. After a week and after complete shedding of the crusts, smooth and erythematous skin appeared. The erythema persisted for more than two months. The patients were free of malignancy and freckling for up to 16 months follow-up.Conclusion: CO2 laser can remove lentiginous pigmentation and prevent or postpone malignancies for a considerable length of time.
Samaneh Mozafarpoor; Ali Asilian; Azadeh Goodarzi; Zahra Ebrahimi; Fatemeh Mokhtari; Zeynab Rastgar Moqaddam
Abstract
Lymphangioma is an unusual congenital malformation of the lymphatic system that affects the skin and subcutaneous tissue. A surgical procedure is among the options for lymphangioma treatment, although it can lead to significant complications. The Nd:YAG Laser appears to be one of the safest therapeutic ...
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Lymphangioma is an unusual congenital malformation of the lymphatic system that affects the skin and subcutaneous tissue. A surgical procedure is among the options for lymphangioma treatment, although it can lead to significant complications. The Nd:YAG Laser appears to be one of the safest therapeutic options rarely proposed to treat oral cavity lesions. This paper comprehensively reviewed the studies published from 2010 to date on the treatment of cutaneous and mucosal lymphangioma with different types of lasers. In the current report, an 18-yearold female presented with a lymphangiomatous lesion on the tongue diagnosed through a pathologic study. The patient initiallyunderwent three sessions of pulsed-dye laser (PDL) therapy that evoked an insignificant response. Therefore, the approach was changed to long-pulsed Nd:YAG laser therapy, and a dramatic response was observed within three sessions of the treatment.
Mehran Golnaz; Fotooei Mahrokh; Goodarzi Azadeh; Forghani Siamak Farokh; Rohaninasab Masoomeh; Ghassemi Mohammadreza; Sadeghi Somayeh; Behrangi Elham
Abstract
Background: Microneedling is recently used to treat skin scars mostly atrophic scars; however, there are limited data about its effectiveness on hypertrophic burn scars. Carbon dioxide (CO2) laser is an effective method for the treatment of burn scars. Here, we aim to compare the efficacy of microneedling ...
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Background: Microneedling is recently used to treat skin scars mostly atrophic scars; however, there are limited data about its effectiveness on hypertrophic burn scars. Carbon dioxide (CO2) laser is an effective method for the treatment of burn scars. Here, we aim to compare the efficacy of microneedling to CO2 laser in the treatment of hypertrophic burn scars in a randomized clinical trial. Methods: Patients with second and third-degree burn scars (n=60) were randomized to receive 3 sessions of microneedling (n=30) or CO2 laser (n=30), 4-6 weeks apart. The outcomes, including physical characteristics of the scar scored by Vancouver Scar Scale (VSS) and patients’ satisfaction with the treatment measured by Visual Analogue Scale (VAS), were investigated at baseline, at the end of the treatment period, and at the 3-month follow-up. Results: The VSS score at the follow-up visit showed a significant reduction from 6.63±1.95 to 3.8±2.3 in the microneedling group and from 7.1+2.3 to 5.6±1.7 in the CO2 laser group; while, the reduced VSS score was significantly higher in the microneedling group (P<0.05), especially in reducing the thickness (P=0.001) and pliability (P=0.001) scores. The patients’ subjective assessments for acne improvement were significantly more satisfactory in the microneedling group (P=0.025).
Conclusion: Microneedling seems to be an effective method to improve hypertrophic burn scars. It also causes better scores in the physical characteristics of scar and the patients’ satisfaction compared to the CO2 laser at the 3-month follow-up.
Nilforoushzadeh Afshar Mohammad Ali; Jaffari Fariba; Ansari Nazli; Moradi Shahram
Volume 10, Issue 3 , 2007, , Pages 181-186
Abstract
Background and aim: The scars of the cutaneous leishmaniasis and psychologic problems of this disease needs different intervention for its correction. Our objective in this study was to compare the efficacy of trichloroacetic acid (TCA) 50 percent solution and CO2 laser for treatment of the atrophic ...
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Background and aim: The scars of the cutaneous leishmaniasis and psychologic problems of this disease needs different intervention for its correction. Our objective in this study was to compare the efficacy of trichloroacetic acid (TCA) 50 percent solution and CO2 laser for treatment of the atrophic scars due to leishmaniasis. Materials and methods: This was a randomized clinical trial perfomed in 92 patients. Patients were randomized into 2 groups, first group were treated with TCA 50 percent solution, once monthly and for maximum of 5 months, second group were treated with CO2 laser that was performed for only one time. Patients were followed at 3 months and 6 months after starting treatment. The improvement of scar was graded by 6-point scale using digital camera and the collected data were analyzed using SPSS software and t, Wilcoxon and Mann-Whitney tests.Results: In this study that 74 females and 18 males were followed, the improvement of scar was 48.13% in the TCA group and 44.87% in the CO2 laser group. This difference was not statistically significant (P=0.55). There was also no significant difference regarding side effects between these 2 groups. Conclusion: The results of our study showed efficacy of topical treatment with 50 percent TCA solution is comparable with CO2 laser in the treatment of leishmaniasis scar. Because of the low cost and simple application of TCA solution in comparison with CO2 laser, we suggest the use of this treatment for correction of leishmaniasis or atrophic scars.
A Asilian; F Salehi
Volume 3, Issue 4 , 2000, , Pages 18-22
Abstract
Background: Nevus spilus can produce considerable disfigurement. There is no specific and successful treatment for this nevus. Objective: The purpose of this study was to evaluate the efficacy of CO2 laser in the treatment of nevus spilus. Patients and Methods: This quasi-experimental clinical trial ...
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Background: Nevus spilus can produce considerable disfigurement. There is no specific and successful treatment for this nevus. Objective: The purpose of this study was to evaluate the efficacy of CO2 laser in the treatment of nevus spilus. Patients and Methods: This quasi-experimental clinical trial was performed on 47 patients with spilus nevus in Al-Zahra Hospital in Isfahan. The diagnosis of nevus spilus was based an clinical and biopsy findings. The efficacy of treatment was evaluated based on tolerability, side effects, improvement according to patient and physician judgment and comparison of photographies, after one year of follow up. The laser used was Sonic LS 500 (Made in Germany) with power of 3 watts, duration of 0.25 seconds and spot size of 3 millimeters. Results: 45 of the patients were female and 2 were male. The mean age of them was 20 years. All the lesions were on the face. Two patients were withdrawn due to inefficacy or infection of test site treatment. In 43 of the 45 remaining patients (95.5%), the treated site healed uneventfully. Recurrence of nevus spilus was seen in a single patient one year after treatment. Conclusion: CO2 laser is an effective therapy for nevus spilus.
