Azadeh Goodarzi; Elham Behrangi; Mohammadreza Ghassemi; Golnaz Mehran; Niloofar Teymoori; Amir Pouyan Ghahremani; Maryam Biglari Abhari
Abstract
Background: Acne vulgaris is among common bothersome skin problems. Recognition of contributing factors would help to prevent acne. Some dietary and inflammatory factors are among suggested etiologies. Accordingly, in this study, the serum levels of calcium, vitamin D, phosphorous ...
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Background: Acne vulgaris is among common bothersome skin problems. Recognition of contributing factors would help to prevent acne. Some dietary and inflammatory factors are among suggested etiologies. Accordingly, in this study, the serum levels of calcium, vitamin D, phosphorous and C-reactive protein (CRP) were determined and compared in acne patients and healthy subjects. Methods: In this case-control study, 144 consecutive subjects with and without acne (moderate-very severe) referred to Rasoul Akram Hospital in 2016 were enrolled. In this regard, the serumcalcium, phosphorous, CRP, vitamin D were determined in the subjects and compared between the groups. Results: The results indicated that serum CRP, calcium, and phosphorous level were alike between the groups (P > 0.05) without any relation to acne severity except CRP. The serum vitamin D level was significantly different (P = 0.0001), but it was not associated with acne severity. Serum calcium levels of males were significantly higher in both groups. Conclusions: Based on our results, it may be concluded that calcium, phosphorous, and CRP levels are not associated with acne incidence, but the serum vitamin D is related to acne presentation. CRP levels were positively associated with acne vulgaris severity.
Rezazadeh Fahimeh; Sokhakian Mahshid
Abstract
Background: Oral lichen planus (OLP) is a common inflammatory disease of unknown origins. Recent studies have considered nutritional factors concerning the pathogenesis of many autoimmune disorders. The objective of the present study was to investigate the plasma levels of magnesium (Mg), calcium (Ca), ...
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Background: Oral lichen planus (OLP) is a common inflammatory disease of unknown origins. Recent studies have considered nutritional factors concerning the pathogenesis of many autoimmune disorders. The objective of the present study was to investigate the plasma levels of magnesium (Mg), calcium (Ca), zinc (Zn), copper (Cu), and iron (Fe) in this disorder. Methods: Included in this observational case-control study was 40 patients with OLP and 40 age and sex matched healthy control subjects. Plasma levels of Mg, Ca, Zn, Cu, and Fe were specified using an autoanalizer. Results: The serum level of Ca was higher, but Mg, Cu, Fe and Zn serum concentration did not differ significantly between the patients with OLP and the healthy controls. Mean Zn concentration was lower in patients with erosive lichen planus compared to the non-erosive group and the healthy controls. However, only the difference between erosive lichen planus patients and healthy participants was significant. The mean Zn level was lower than the normal range (70 µg/dl) in both the cases and controls. The concentration of Fe was significantly higher in men male patients than in females; however, the difference between men and women was not significant in the healthy control group. The mean Cu/Zn ratios in erosive and patient groups were slightly higher compared with the controls. Conclusion: Trace elements such as Ca may play a role in the ethiopathogenesis of OLP. Nevertheless, other elements such as Zn or Cu may influence OLP, which requires further evaluation on larger samples.
Hamideh Moravvej; Maryam Yousefi; Nahid Mohtasham; Nelda Saadat; Hamid Reza Haghighatkhah
Volume 11, Issue 3 , 2008, , Pages 108-112
Abstract
Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium ...
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Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium homeostasis and radiographic bone changes in short course treatment with oral isotretinoin in severe acne.Methods: 1,25-dihydroxy vitamin D and 25-hydroxy vitamin D, calcium, phosphate, Parathyroid hormone and axial spine , femoral neck radiographies were measured in 30 nodulocystic acne patients ( 17 -28 years ) before and after twenty weeks of treatment with oral isotretinoin at the recommended dose (0.75 -1 mg/kg/day) .Results: vitamin D metabolites, calcium, phosphate, Parathyroid-hormone did not change significantly and hyperostosis and other sclerotic change were not observed in any patients.Conclusion: Short course treatment with oral isotretinoin at the recommended dose did not lead to any significant changes in serum vitamin D metabolites, calcium, phosphate and Parathyroid hormone and has no effects on bone radiography in acne patients.
S Family
Volume 5, Issue 1 , 2001, , Pages 3-8
Abstract
Background: Psoriasis is a common disease of the skin. Metabolic disorders have been suggested in the etiology of psoriasis. Objective: As hypocalcemia has been reported to provoke psoriasis, we studied the blood calcium level in this disease. Patients and Methods: In this case-control study, we measured ...
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Background: Psoriasis is a common disease of the skin. Metabolic disorders have been suggested in the etiology of psoriasis. Objective: As hypocalcemia has been reported to provoke psoriasis, we studied the blood calcium level in this disease. Patients and Methods: In this case-control study, we measured blood calcium level in 120 psoriatic patients visited in outpatient clinic or admitted in Ghahem Hospital in Mashhad and compared to 120 age and sex matched normal controls. Results: Considering blood calcium level of 8.5-10.5 mg/dl as normal, 17 psoriatic patients (14%) and 6 controls (5%) were hypocalcemic (P<0.05). Conclusion: As hypocalcemia in psoriatic patients was significantly more common in this study, estimation of blood calcium level is recommended in psoriasis.