Hajheydari Zohreh; Saeedi Majid; Hosseinzadeh Mohammad
Abstract
Background: Seborrheic dermatitis is a common chronic relapsing inflammatory skin disease with unknown etiology. Using zinc and selenium supplements have shown some relieving effects on the symptoms of the disease. The present study was conducted to determine the relationship between serum selenium, ...
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Background: Seborrheic dermatitis is a common chronic relapsing inflammatory skin disease with unknown etiology. Using zinc and selenium supplements have shown some relieving effects on the symptoms of the disease. The present study was conducted to determine the relationship between serum selenium, zinc, and copper levels with seborrheic dermatitis. Methods: A prospective case-control study was performed on 30 patients with seborrheic dermatitis and 30 age and sex-matched healthy volunteers as a control group. Trace elements were measured by atomic absorption spectrophotometer in both groups. Results: The mean serum selenium, zinc, and copper levels were 98.90 ± 27.61 ?g/dL, 91.27 ± 10.84 ?g/dL, and 100.9 ± 20.06 ?g/ dL in case groups, respectively. In the control group, the mean serum selenium, zinc, and copper levels were 91.61 ± 15.74 ?g/dL, 94.03 ± 11.11 ?g/dL, and 96.5 ± 15.82 ?g/dL, respectively. There was no significant difference between the mean serum selenium, zinc, and copper levels in case and control groups (P>0.05). Conclusions: Although no statistically significant relationship was observed in serum selenium, zinc, and copper levels between the cases and controls, the serum selenium level among patients in case group was higher than that in the healthy subjects.
Triana Agustin; Githa Rahmayunita; Rinadewi Astriningrum; Eliza Miranda; Erdina HD Pusponegoro; Sandra Widaty
Abstract
Background: Seborrheic dermatitis (SD) is an inflammatory disease affecting seborrheic areas of the skin. Scalp SD varies from mild, manifesting as dandruff, to erythematous lesions with greasy scales. SD negatively affects patients’ quality of life.Methods: This is a cross-sectional study investigating ...
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Background: Seborrheic dermatitis (SD) is an inflammatory disease affecting seborrheic areas of the skin. Scalp SD varies from mild, manifesting as dandruff, to erythematous lesions with greasy scales. SD negatively affects patients’ quality of life.Methods: This is a cross-sectional study investigating the relationship between quality of life and disease severity in patients with dandruff and scalp SD at the Dermatology and Venereology Outpatient Clinic, of Dr. Cipto Mangunkusumo General Hospital. SD severity was assessed by the modified Seborrheic Dermatitis Area and Severity Index (SDASI), and quality of life was assessed by the Indonesian version of the Dermatology Life Quality Index (DLQI).Results: A total of 96 subjects with scalp SD were recruited, comprising 86 subjects with mild SD and 10 subjects with moderate SD. DLQI scoring revealed 5 subjects (5%) felt no effect of SD at all on their lives, 10 subjects (10%) felt small effect, 38 subjects (40%) felt moderate effect, 32 subjects (33%) felt very large effect, and 2 subjects (2%) felt extremely large effect on their lives. There is no significant difference between SD severity with the average DLQI score in the mild SD group (8.73 ± 4.9) and the moderate SD group (9.30 ± 6.13), P=0.737. Furthermore, no significant difference was found between the DLQI scores in the male (9.86 ± 4.7) and female (8.18 ± 5.13) groups, P=0.116. Spearman’s correlation analysis revealed no significant relationship between age and DLQI scores (r=-0,104, P=0,313).Conclusions: Our study concludes that SD negatively affects the quality of life.
Rastegar Hosein; Ashtiani Hamidreza Ahmadi; Baghaei Mohammad; Bokaei Saeid; Ehsani Amirhoushang; Noormohammadpour Pedram; Azizahari Sahar; hanmohammad Ramin
Volume 12, Issue 3 , 2009, , Pages 82-85
Abstract
Background: Dandruff especially with itching and inflammation is a common complaint among patients in the clinic and its treatment is much challenging. Chemical anti fungal substances used in antidandruff shampoos are common treatments. The aim of this study was to compare the clinical efficacy of two ...
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Background: Dandruff especially with itching and inflammation is a common complaint among patients in the clinic and its treatment is much challenging. Chemical anti fungal substances used in antidandruff shampoos are common treatments. The aim of this study was to compare the clinical efficacy of two of these anti dandruff substances, climbazole and piroctone olamine in the treatment of dandruff and seborrheic dermatitis in shampoos with herbal extracts. Methods: One hundred and twenty men with scalp dandruff of the same severity, between 20-30 years old and in the same occupational condition in terms of sun exposure or environmental pollution were selected and divided randomly into two 60-subject groups. After each shampoo was applied 3 times a week for 5 weeks one in group 1 and the other in group 2, patients were assessed for existence of itching and redness of scalp and reduction in dandruff and results were compared between two groups. Results: Itching and redness were completely cured in both groups after treatment. Dandruff was completely cured in 80% of patients and reduced in 20% of patients in climbazole group (p < 0.001), though completely cured in 55% of patients and reduced in 45% of patients in piroctone olamine group (p < 0.001). Climbazole was over piroctone olamine in reduction of dandruff with significant difference (p < 0.01). Conclusion: Both shampoos containing climbazole or piroctone olamine beside herbal extracts are effective in the reduction of dandruff and relief of other seborrheic dermatitis symptoms but climbazole seems to be more effective than piroctone olamine in the treatment of dandruff.
SZ Ghodsi; H Ghani Nezhad; L Farpoor; A Ali Mardani; A Taheri; P Mansoori
Volume 8, Issue 2 , 2005, , Pages 115-120
Abstract
Background: Geographic tongue is an inflammatory disorder of unknown etiology that affects the epithelium of the tongue. It has been associated with several cutaneous diseases. Objective: To determine the prevalence of geographic tongue and its association with other cutaneous diseases in patients referred ...
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Background: Geographic tongue is an inflammatory disorder of unknown etiology that affects the epithelium of the tongue. It has been associated with several cutaneous diseases. Objective: To determine the prevalence of geographic tongue and its association with other cutaneous diseases in patients referred to the dermatology clinic of Razi hospital. Patients and methods: A cross-sectional study was performed on all patients referred to one of the dermatology clinics of Razi hospital between February 21 and March 18, 1996 to determine the prevalence of geographic tongue and other diseases. Results: One-thousand and one-hundred and sixty referred patients were studied. The prevalence of geographic tongue was 6.2%. There was a statistically significant association between geographic tongue and seborrheic dermatitis (P=0.0053). Conclusion: Geographic tongue is associated with some cutaneous diseases. Detection of these associations could be a clue to the etiology and pathogenesis of geographic tongue.
F Pazeshkpoor; M Soleimani
Volume 5, Issue 3 , 2002, , Pages 41-44
Abstract
Langerhans cell histiocytosis includes a broad spectrum of clinical diseases resulted from proliferation and tissue infiltration of differentiated langerhans cells. This term includes Letterer-siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma and congenital reticulohistiocytosis that ...
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Langerhans cell histiocytosis includes a broad spectrum of clinical diseases resulted from proliferation and tissue infiltration of differentiated langerhans cells. This term includes Letterer-siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma and congenital reticulohistiocytosis that are more common in children than adults. This entity has recently been classified into restricted and extensive forms according to the number of involved organs. We report here in a 41-year-old man who developed Langerhans histiocytosis and presented with seborrheic dermatitis-like skin signs and external ear polypoid lesion without other organ involvement.
M Emad; SMN Hosseini
Volume 3, Issue 3 , 2000, , Pages 18-22
Abstract
Background: Seborrheic dermatitis is one of the most common skin diseases. Objective: The purpose of this study was to compare the topical and oral ketoconazole in treatment of intractable cases of seborrheic dermatitis referring to Faghihi Hospital in Shiraz. Patients and Methods: This study was performed ...
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Background: Seborrheic dermatitis is one of the most common skin diseases. Objective: The purpose of this study was to compare the topical and oral ketoconazole in treatment of intractable cases of seborrheic dermatitis referring to Faghihi Hospital in Shiraz. Patients and Methods: This study was performed on 80 cases of intractable seborrheic dermatitis in 1376-1378. The patients were randomized in two treatment groups. Group included 40 patients who were treated with topical ketoconazole cream 2% two times per day for 4 weeks, and group 2 included 40 patients who received oral ketoconazole 200 mg daily for 4 weeks. Results: Topical ketoconazole clinically cured 35 (87.5%) and oral ketoconazole cured 38 (95%) of patients. This difference was not statistically significant. However topical ketoconazole was accompanied with a lower frequency of side effects than the systemic form. Conclusion: Both topical and oral ketoconazole can be regarded as a highly effective and safe treatment for seborrheic dermatitis.