Bordera Gabriel Buendia; Parada Jorge Gaviria; Giménez Maribel Marti; Pérez Maria de los Llanos; Morell Jiuia Oliva; Marmol Gregorio Viera
Abstract
The use of high-power diode laser with a wavelength of 755 nm is an effective and safe method for the correction and partial and/or total elimination of pigmented lesions, specifically solar lentigines. This wavelength has yet not been used in diode lasers to treat solar lentigines. Side effects are ...
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The use of high-power diode laser with a wavelength of 755 nm is an effective and safe method for the correction and partial and/or total elimination of pigmented lesions, specifically solar lentigines. This wavelength has yet not been used in diode lasers to treat solar lentigines. Side effects are the usual ones, including darkening and scab formation. Our patient was a 40-year-old woman of Caucasian origin and IV Fitzpatrick phototype, who presented with solar lentigines of different sizes and clear edges. The applied treatment was a high-power diode laser of 755 nanometer (nm), 21 millisecond (ms) long pulse and 25 J/cm2 fluence. Initially, the darkening of the lesion occurred, followed by the appearance of a scab, which remitted 10 days after. The use of high-power diode laser of single pulse at 755nm, 25J/ cm2 and 21ms, proved effective and safe concerning the removal of benign pigmented lesions.
Seirafi Hassan; Fateh Soheil; Farnaghi Farshad; Ehsani Amir Hooshang; Noormohammadpoor Pedram
Volume 13, Issue 1 , 2010, , Pages 1-5
Abstract
Background: Although cryotherapy is still the first-line therapy for solar lentigines, due to side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment specific lasers should be considered as initial treatment. The aim of this study was to ...
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Background: Although cryotherapy is still the first-line therapy for solar lentigines, due to side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment specific lasers should be considered as initial treatment. The aim of this study was to evaluate the efficacy and safety of cryotherapy in comparison with 595-nm pulsed dye laser (PDL) with cutaneous compression in the treatment of solar lentigines. Method: Twenty two patients (skin type II- IV) with facial or hand lentigines completed this study. Lesions of one side of the face or each hand were randomly assigned and treated with either cryotherapy or PDL. Treatments were performed with radiant exposures of 10 J/cm2, 7mm spot size and 1.5ms pulse duration with no epidermal cooling. Photographs were taken before treatment and one month later. The response rate and side effects were compared. Results: PDL was more likely to produce substantial lightening of solar lentigines than cryotherapy, especially in skin types III and IV (n=8, n=9; P0.05). PIH was only seen in the cryotherapy group. PDL group only showed minimal erythema. No purpura was observed. Conclusion: PDL with compression is superior to cryotherapy in the treatment of solar lentigines in darker skin types.
Hasan Edalatkhan; Nayereh Amini Sani; Somayeh Zeynizadeh
Volume 10, Issue 1 , 2007, , Pages 54-59
Abstract
Background and aim: It seems that melanocytic nevi, freckle and lentigo are more common in women with melasma, and a common genetic background may exist. In this study the prevalence and number of lentigo, freckle and melanocytic nevus were compared in women with and without melasma.Materials and methods: ...
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Background and aim: It seems that melanocytic nevi, freckle and lentigo are more common in women with melasma, and a common genetic background may exist. In this study the prevalence and number of lentigo, freckle and melanocytic nevus were compared in women with and without melasma.Materials and methods: In a case-control study, 120 women with melasma (case group) and 120 women without melasma (control group), matched for age, were examined by a dermatologist. The singnosis of lesions were done only by clinical observation. Data were analysed by SPSS software using chi-square (or Fisher) test and p<0.05 was considered as significant.Results: The mean age was 29.97±6.6 years in case group and 29.7±6.7 in control group (non significant). Prevalence of freckles was higher in control group (24.3% versus 4.16%, p<0.001). 77 patients (64.1%) in case group and 20 (16.6%) of control group had lentigo (p<0.001). The mean number of lentigo in case group was 25.2 and in control group was 8 (p=0.01). The prevalence of melanocytic nevus in control group was lower than case group (96.6% versus 98.3%), but this difference was not significant. The mean number of melanocytic nevi was 2.8 in control group and 13.2 in case group (p<0.001). Campbell de Morgan angiomas were seen in 26 (21.8%) of case group and in 6 (5%) of control group (p<0.001). The mean number of these angiomas was 1 in control group and 5.2 in case group (p=0.02).Conclusion: The prevalence and number of melanocytic nevi were higher in women who had melasma. Common factors or genes may have a role in appearing of melasma and moles.
Raziee Morteza; Balighi Kamran; Shabanzadeh-Dehkordi Hossein; Rabati Reza Mahmoud
Volume 9, Issue 4 , 2006, , Pages 308-312
Abstract
Background and aim: Solar lentigines are common sun-induced benign melanocytic proliferations that present a significant cosmetic problem for many middle- aged and elderly patients. The purpose of this study was to assess the efficacy of cryotherapy in comparison to trichloroacetic acid (TCA) 33% on ...
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Background and aim: Solar lentigines are common sun-induced benign melanocytic proliferations that present a significant cosmetic problem for many middle- aged and elderly patients. The purpose of this study was to assess the efficacy of cryotherapy in comparison to trichloroacetic acid (TCA) 33% on solar lentigines on the back of the hands (SLBH).Materials and Methods: Each hand of 33 patients with SLBH was treated randomly with either cryotherapy or TCA 33% solution. Photographs of the hands were taken prior to and two months following the treatment. Therapeutic response and side-effect were compared using chi-square test.Results: Twenty five patients completed the study. Cryotherapy was more likely to produce substantial lightening of the solar lentigines than TCA 33% solution (P=0.025) but was more painful and took longer to heal. Post inflammatory hyperpigmentation (PIH) was almost equal in two types of treatment. Statistically, better results were seen in lower Fitzpatrick's skin types (P<0.01).Conclusion: Cryotherapy appears to be superior to TCA 33% solution in the treatment of SLBH particularly in lower Fitzpatrick skin types. PIH is the major complication of both particularly in higher Fitzpatrick skin types. Generally, the major criterion for treatment of SLBH with cryotherapy or TCA is Fitzpatrick's skin type.
Toosi Parviz; Dadras Mohammad Shahidi; Sadiqha Afshin; Farshi Hamideh Moravej
Volume 9, Issue 4 , 2006, , Pages 324-330
Abstract
Background and aim: It is possible to use light sources suxh as lasers to destruct melanosomes and treat pigmented skin lesions. One of the most commonly used laser systems is Q switched ruby laser with a wave-length of 694 nm. This study was performed to evaluate the efficacy of the Q switched ruby ...
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Background and aim: It is possible to use light sources suxh as lasers to destruct melanosomes and treat pigmented skin lesions. One of the most commonly used laser systems is Q switched ruby laser with a wave-length of 694 nm. This study was performed to evaluate the efficacy of the Q switched ruby laser in the treatment of pigmented skin lesions including lentigines (simplex or solar) and café-au-lait macules.Materials and Methods: After physical examination for ruling out the possibility of malignancy by two dermatologists, patients were treated with Q switched ruby laser. Response to treatment was categorized in four groups of equal interval according to the 0-100% lesion lightening.Results: Ninetyy patients including 81 patients with solar lentigo and 9 cases of lentigo simplex were recruited into this study. Mean±standard deviation (SD) of the number of treatment sessions for solar lentigo and lentigo simplex cases were 1.0 ± 0.5 and 3.6 ± 1.3 , respectively. Although the mean of sessions was increased in darker skin types, there was no statistically significant difference between different skin types (p=0.335). In addition, there was no significant relation between mean treatment sessions and location of the lesions (p=0.685). Cure rate was 100% in all lentigo cases and after a mean ±SD of 8.7±2.3 months follow up there was no recurrence. Also, there was neither pigmentary change nor folliculitis during treatment. In 7 cases with café-au-lait macules, the mean±SD score of improvement was 2.4 ± 0.8, which was achieved after 3.1±0.4 treatment sessions. In 6 cases whom were followed up for 10.2 ± 3.1 months, despite primary disappearance, recurrence of café-au-lait macules was observed. Conclusion: It seems Q switched ruby laser is an appropriate method for treatment of lentiginous lesions in caucasians with Fitzpatrick's skin types II to IV.