Farideh Jowkar; Najmeh Radgoodarz; Nasrin Saki; Alireza Heiran
Volume 19, Issue 1 , 2016, , Pages 11-15
Abstract
Background: Laser treatment is a rapid, non-invasive procedure for long-term hair removal. Lasers operate based on the principle of selective photothermolysis and target melanin in the hair follicle. We intend to determine the level of hirsute patient satisfaction with the alexandrite laser hair removal ...
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Background: Laser treatment is a rapid, non-invasive procedure for long-term hair removal. Lasers operate based on the principle of selective photothermolysis and target melanin in the hair follicle. We intend to determine the level of hirsute patient satisfaction with the alexandrite laser hair removal procedure.Methods: In this cross-sectional study 82 hirsute patients with unwanted hair on their faces were enrolled. The patients received treatment with a 755 nm alexandrite laser (GentleLASE, Candela Corporation, USA). We documented their level of satisfaction with this laser in terms of hair removal. Laser therapy, electrolysis, and depilation were compared.Results: Patients ≥30 years old expressed greater satisfaction compared to those <30 years of age (P=0.03). Patients with medically related hirsutism had the same satisfaction as the idiopathic hirsute group (P=0.81). Patients rated laser hair removal as 4.12 compared to depilation and 3.96 compared to electrolysis. From total patients, 60.97% would recommend laser treatment to other hirsute patients. There were 79.3% of patients who expressed satisfaction with alexandrite laser hair removal.Conclusions: Most patients expressed satisfaction with the alexandrite laser hair removal procedure. Age played a significant role in patient satisfaction.
Jahangir Majid; Qayoom Seema; Peerzada Sajad; Naseer Choh; Rifat Ara; Kafeel Khan
Volume 18, Issue 1 , 2015, , Pages 1-5
Abstract
Background: Hirsutism, a common clinical condition, not onlycauses cosmetic concern but may also be a sign of underlyingdisease. Polycystic ovary syndrome (PCOS) is an importantand common cause of hirsutism. In fact, many women withPCOS present as hirsutism. This study assessed young Kashmiriwomen presenting ...
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Background: Hirsutism, a common clinical condition, not onlycauses cosmetic concern but may also be a sign of underlyingdisease. Polycystic ovary syndrome (PCOS) is an importantand common cause of hirsutism. In fact, many women withPCOS present as hirsutism. This study assessed young Kashmiriwomen presenting as hirsutism, for ultrasonographic evidence ofpolycystic ovaries (PCO), in addition to recording their clinical andhormonal profile. The purpose of this study was to determine theprevalence of polycystic ovary syndrome using ultrasonography,in young Kashmiri women presenting as hirsutism.Method: In total, one hundred and seventy (170) consecutive youngKashmiri women presenting with chief complaint of hirsutismwere assessed. A total of eighty (80) age matched non- hirsutefemales having normal menstrual cycles, served as controls. Theovaries were visualised by transabdominal ultrasonography (USG).The serum was analysed for luteinizing hormone (LH), folliclestimulating hormone (FSH), total testosterone (tT), prolactin(PRL) and thyroid stimulating hormone (TSH).Result: The study showed prevalence of 61.18% PCOS in youngKashmiri women presenting as hirsutism. PCOS was diagnosed in35.11% hirsute women with regular menses and ultrasonographywas used to identify PCO in 90.35% patients. Biochemicalhyperandrogenemia was present in 70.15% of the patients andthe LH/FSH ratio increased in 81.73% of the patients.Conclusion: The results of this study show a high prevalence ofPCOS in young Kashmiri women presenting as hirsutism andalso highlights the fact that PCOS is not necessarily associatedwith menstrual disturbances. Therefore, all hirsute women, evenwith regular menses, should be evaluated for PCOS.
Davoudi Seyyed Masoud; Behnia Fereydoun; Gorouhi Farzam; Saeed Keshavarz; Mansour Nassiri Kashani; Alireza Firooz
Volume 9, Issue 4 , 2006, , Pages 319-323
Abstract
Background and aim: Laser is one of the most recent techniques which has widespread use in the treatment of many skin diseases. This technique has been successfully used to remove unwanted hairs in hirsutism. The aim of this study was to evaluate and compare the efficacy and safety of long-pulsed 755 ...
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Background and aim: Laser is one of the most recent techniques which has widespread use in the treatment of many skin diseases. This technique has been successfully used to remove unwanted hairs in hirsutism. The aim of this study was to evaluate and compare the efficacy and safety of long-pulsed 755 nm alexandrite and long-pulsed 1064 nm Nd: YAG lasers individually and in combination for permanent hair removal. Materials and Methods: This single-blind randomized clinical trial was conducted on 25 patients. They were treated by alexandrite or Nd: YAG or combination of them in 4 sessions with 8 weeks intervals. The treatment was applied on their medial and lateral sides of both legs. All the parameters of the systems were set on the company defaults. Subjects were evaluated 1 and 8 months after completion of the treatment. Hair count was measured by Visiomed device and digital camera photographs every session. To calculate mean hair reduction, the difference between hair count before and after treatment was divided by hair count before treatment. Pain severity, measured by Visual Analogue Scale (VAS), and side effects (bullae, scar and pigmentation changes) were recorded every session. The data were analyzed with ANOVA, post hoc Tukey and chi square tests. Results: Fifteen patients completed the study and 10 patients were excluded due to appearance of bullae in 2 patients and refuse to continue in 8 patients. The mean hair reduction measured by Visiomed 8 months after last treatment was: 61.96 ±21.09, 60.03±23.40 and 68.05±21.23 percent for alexandrite, Nd: YAG and combination therapy, respectively. When digital camera photos were used for measurement of hair reduction these values were 85.99±11.62, 73.60±16.57 and 79.61±18.08 percent, respectively. The differences between the systems were not significant (ANOVA, P>0.05). In paired comparison of the systems, no significant differences were observed either (Tukey test). The incidence of adverse effects (hyperpigmentation) and pain severity were significantly greater in area received combination therapy (P=0.001).Conclusion: Both alexandrite and Nd:YAG laser systems were effective in hair removal. In contrast, combination therapy did not have more efficacy and also caused more side effects.
M Akhyani; M Danesh Pazhooh; M Barzegari; N Ghandi; M Ghiasi; Z Chenari; S Soudavari
Volume 9, Issue 3 , 2006, , Pages 242-249
Abstract
Background and aim: Hirsutism is a common clinical problem among women; however estimates regarding its prevalence in our population are limited. The objective of this study was to estimate the frequency and features of hirsutism in yound women in Iran.Materials and Methods: This descriptive-cross sectional ...
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Background and aim: Hirsutism is a common clinical problem among women; however estimates regarding its prevalence in our population are limited. The objective of this study was to estimate the frequency and features of hirsutism in yound women in Iran.Materials and Methods: This descriptive-cross sectional study was performed on 800 female (18-25 years) medical students of Tehran medical universities in 1999. Evaluation included a history and a modified Ferriman-Gallwey hirsutism score in four different androgen-sensitive skin areas. The volunteers recorded their weight and height, the presence of menstural dysfuncion, acne, positive family history for hirsutism, as well as ingestion of oral contraceptive pills, corticosteroids or anabolic steroids using a questionnaire. Data were analyzed using chi-square test and P<0.05 was considered significant.Results: The frequency of hirsutism in our population was 22.8% (183 of 800). 17.3%, 5.1% and 0.3% of the population studied had mild, moderate and severe hirsutism, respectively. The prevalence of obesity (body mass index > 25), acne, positive family history for hirsutism, menstrual dysfunction, and consumption of corticosteroid and OCP was significantly higher in hirsutes.Conclusion: Hirsutism is a very common abnormality in this group of woman in Iran. Higher hirsutism frequency in this survey comparing to previous records in other population shows that the hirsutism definition and scoring system should be modified due to racial/ethnic variations in terminal hair quantity and distributions and different concept of this abnormality in each population.
M Emam Ghoreishi; R Salman Pour; MR Panjeh Shahin
Volume 8, Issue 3 , 2005, , Pages 218-223
Abstract
Background: Hirsutism can result in cosmetic and psychological problems in women. Because of diverse etiological factors, treatment with a single drug is not usually successful. On the other hand, treatment of Hirsutism can be associated with adverse effects. Objective: To evaluate the efficacy of a ...
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Background: Hirsutism can result in cosmetic and psychological problems in women. Because of diverse etiological factors, treatment with a single drug is not usually successful. On the other hand, treatment of Hirsutism can be associated with adverse effects. Objective: To evaluate the efficacy of a herbal ointment consisted of leguminosea spp. and zingiberaceae spp. extracts in reduction of hair density in hirsute women. Patients and Methods: In an open clinical trial 10 hirsute women were treated with a herbal ointment 3 times a day for 2 weeks in 3 consecutive months. Pre and post-treatment assessment of number, length, and diameter of hairs were done in individual patients. Paired T-test was used for statistical analyses. Results: After 3 treatment courses the mean number of the hairs showed significant reduction in comparison with pre-treatment values. Some patients mentioned that treatment resulted in softer, thinner and lighter hairs. Conclusion: The studied herbal ointment was effective in hair density reduction in hirsute patients. It was also a simple, inexpensive and safe treatment for Hirsutism.
P Toosi; F Malekzad; A Sedigha
Volume 8, Issue 1 , 2004, , Pages 7-14
Abstract
Background: The theory of selective photo-thermolysis led to the development of a variety of different laser systems which range from the shorter spectrum of 694nm ruby laser to the middle with the 755nm alexandrite and 810nm diode lasers to the long end with the 1064nm (Nd:YAG) laser. Objective: A systematic ...
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Background: The theory of selective photo-thermolysis led to the development of a variety of different laser systems which range from the shorter spectrum of 694nm ruby laser to the middle with the 755nm alexandrite and 810nm diode lasers to the long end with the 1064nm (Nd:YAG) laser. Objective: A systematic review on the clinical trials with use of various laser sources for hair removal. Methods: All clinical trials related to hair removal lasers in 1998-2003 were selected. After elimination of heterogenicity sources in data, results were synthesized on the basis of laser type and were compared using ANOVA and t tests, P
H Ansarin; R Mehregan; J Hosseini
Volume 7, Issue 3 , 2004, , Pages 156-165
Abstract
Background: Monotherapy is not usually effective in the treatment of hirsutism. Objective: Comparison of 2 therapeutic regimens in the treatment of hirsutism. Patients and methods: In this open parallel controlled clinical trial, 101 Patients suffering from hirsutism were randomly divided into two equal ...
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Background: Monotherapy is not usually effective in the treatment of hirsutism. Objective: Comparison of 2 therapeutic regimens in the treatment of hirsutism. Patients and methods: In this open parallel controlled clinical trial, 101 Patients suffering from hirsutism were randomly divided into two equal groups. 50 patients were treated with spironolactone (50 mg/day) plus cyproterone compound (From 5th to 26th day of menstrual cycle) and the other group (51 patients) received cyproterone acetate 50 mg/day (From 5th to 14th day of menstrual cycle) in addition to the above mentioned drugs for 6 months. The serum level of sex hormones and hirsutism score (Ferriman-Gallway) were determined before and after treatment. T-test, chi-2 test and linear regression analysis were used for data analysis. Results: Mean hirsutism score was 22.12±0.34 in first group and 22.15±0.34 in second group before treatment. Hirsutism score was reduced to 12.74±0.32 after treatment with 3 drugs and reduced to 16.73±0.35 after treatment with 2 drugs. This reduction was significantly more in the first group after adjustment for other confounding variables (P<0.001). Conclusion: These two therapeutic regimens were both effective in the treatment of hirsutism without serious hepatic, renal and metabolic side effects. Treatment with 3 anti-androgen drugs was more effective in reduction of hirsutism scores.
F Farnaghi; H Seyrafi; N Zarrinpour
Volume 6, Issue 1 , 2002, , Pages 21-25
Abstract
Background: Hirsutism is a common clinical problem with different etiologic factors. Hence, clinical and laboratory studies are necessary to find these factors. Objectives: To determine the etiologic factors of hirsutism with clinical and paraclinical studies including TSH, DHEA-S, LH/FSH, testosterone, ...
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Background: Hirsutism is a common clinical problem with different etiologic factors. Hence, clinical and laboratory studies are necessary to find these factors. Objectives: To determine the etiologic factors of hirsutism with clinical and paraclinical studies including TSH, DHEA-S, LH/FSH, testosterone, prolactin, 17-OH progesterone and sonography of ovary. Patients and Methods: This cross sectional study evaluated clinical and paraclinical findings of 110 hirsute patients who referred to the dermatology clinic of Tehran Razi Hospital during a period of one and half years, in 2000-2001. Results: Polycystic ovary syndrome (PCOs) was diagnosed in 54 patients (49%) including 14 cases (26%) with regular menstruation. 43 patients (39%) had laboratory findings compatible with PCOs and LH/FSH>3 was the most valuable one in 41 patients (37%). 53 patients (48%) with regular menstrual cycles and normal laboratory and sonographic findings had idiopathic hirsutism. Late onset adrenal hyperplasia due to partial 21-hydroxylase deficiency was diagnosed in two cases (1.8%). In one patient with irregular menstruation, pituitary prolactinoma was confirmed by brain imaging techniques. Conclusion: Routine laboratory evaluations are mandatory in the management of hirsutism, regardless of menstruation cycles.