Behzad Khodaei; Simin Seyedpour; Bahareh Gholami; Kambiz Kamyab Hesari; Seyed Ahmad Seyed Alinaghi; Maryam Nasimi
Abstract
Background: Nail disorders present with a wide range of manifestations. The problems associated with nail biopsiesmake the diagnosis even more challenging. Identifying the most common features of each nail disorder can prevent unnecessary biopsies and facilitate early diagnosis.Methods: We conducted ...
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Background: Nail disorders present with a wide range of manifestations. The problems associated with nail biopsiesmake the diagnosis even more challenging. Identifying the most common features of each nail disorder can prevent unnecessary biopsies and facilitate early diagnosis.Methods: We conducted a cross-sectional study on 528 pathology reports, documented from March 2018 to March 2019 in the Razi Dermatopathology Hospital, Tehran, Iran. We extracted the demographic data and the nails’ clinical and pathologic presentations. We used Fisher’s exact test to determine the nail features’ clinicopathological correlations.Results: The mean age of the 359 included patients was 38.81 ± 18.11 years, and 50.81% were male. Benign melanonychia (12.82%), traumatic nail (11.96%), and junctional nevus (11.11%) were the most prevalent disorders. Onycholysis (P < 0.001), longitudinal ridges (P < 0.001), subungual hyperkeratosis (P = 0.003), dystrophy (P = 0.017), discoloration (P = 0.052), and pitting (P < 0.001) correlated significantly with nail psoriasis. The presence of subungual hyperkeratosis, onycholysis, and longitudinal ridges significantly increased the odds of nail lichen planus. Only 6.79% of patients with longitudinal melanonychia had malignant melanoma, while most (26.54%) correlated with benign melanonychia.Conclusions: A detailed examination can narrow the differential diagnosis and avert unnecessary biopsies. However, in high-risk cases, physicians should regularly monitor the nails’ changes and response to treatment.
K Nabizadeh; A Nasiri; A Zamanian
Volume 5, Issue 1 , 2001, , Pages 20-26
Abstract
Background: The nails of hands and feet are involved in the course of many dermatoses and some systemic diseases. They may have diagnostic or prognostic value in some diseases. Objective: The aim of this study was to evaluate nail lesions in patients referred to Dermatology Department of Sina Hospital ...
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Background: The nails of hands and feet are involved in the course of many dermatoses and some systemic diseases. They may have diagnostic or prognostic value in some diseases. Objective: The aim of this study was to evaluate nail lesions in patients referred to Dermatology Department of Sina Hospital in Hamadan from April 1999 to April 2000. Patients and Methods: This cross-sectional descriptive study was done by preparation of a checklist and necessary information was collected by examining all the patients and recording the nail changes. The data were analyzed with EP16 software. Results: Among 2269 patients visited during this year, 630 persons (27.7%) had nail lesions. Eczema and psoriasis were the most common dermatosis with nail lesions (23.5% and 12%, respectively). Fifty-five patients (8.7%) had only nail diseases. Ridging was the most common nail lesion in hands (32%) and in feet (42%). Conclusion: Approximately one third of patients referred to the dermatologic clinic of Sina Hospital in Hamadan had nail lesions.
