Abbas Zamanian; Ahmadreza Mobaien
Volume 13, Issue 4 , 2010, , Pages 128-130
Abstract
Background: Rosacea is a chronic skin disease with an unknown etiology. Some reports have suggested an increased prevalence of Helicobacter pylori infection in rosacea patients, but it is controversial. This study was designed to compare the prevalence of H. pylori and serological cag A+ species between ...
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Background: Rosacea is a chronic skin disease with an unknown etiology. Some reports have suggested an increased prevalence of Helicobacter pylori infection in rosacea patients, but it is controversial. This study was designed to compare the prevalence of H. pylori and serological cag A+ species between the rosacea patients and the healthy control group. Methods: This case-control study was performed on 30 rosacea patients and 60 healthy individuals as the control group. The results were reported based on clinical and serological enzymelinked immunosorbent assay IgG antibody and cag A examination in two groups. Results: Mean age of the rosacea patients and the control group was 45.8 ± 14.05 and 41.4 ± 12.3 years respectively and 56.7% of the patients and 86.2% of controls were infected by H. Pylori (P=0.002). Furthermore, cag A+ was seen in 53.5% of the patients and 50% of the controls (P=0.23). Conclusion: This study showed a reduction in the prevalence of Helicobacter Pylori in acne rosacea patients compared to other studies in the world. The authors believe that it is necessary to conduct more studies to demonstrate the exact prevalence of this organism in Iranian rosacea patients.
T Rashidi; A Alamdari Mahd; A Hamzeh Zadeh; R Talebi
Volume 7, Issue 3 , 2004, , Pages 152-155
Abstract
Background: Recurrent aphthous stomatitis (RAS) is a common disease, which several etiologic factors have been considered for it. The infectious agents and immunological factors are the most suspected causes. Recently a few studies with varied results have been done to clarify the role of Helicobacter ...
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Background: Recurrent aphthous stomatitis (RAS) is a common disease, which several etiologic factors have been considered for it. The infectious agents and immunological factors are the most suspected causes. Recently a few studies with varied results have been done to clarify the role of Helicobacter Pylori (H.pylori) in etiology of RAS. Objective: To find correlations between serum IgG and IgA levels to Helicobacter Pylori and RAS. Patients & methods: A total number of 29 patients with RAS referred to Urmia skin hospital were included in this case-control study. Control group consisted of 57 persons and was chosen from healthy individuals. Blood samples were taken and blood levels of IgG and IgA antibodies of patients and control were measured by ELISA method and collected data were analyzed by chi-square test. Results: IgG antibodies to H.pylori were found in the sera of 75.9% of RAS patients and 66.7% of controls. IgA antibodies were detected in 51.9% of RAS and 70.9% of controls. These differences were not statistically significant. Conclusion: There was no significant difference between IgG and IgA levels to Helicobacter Pylori in patients with RAS compared to control group.
P Toosi; L Gachkar; M Rostami Moghaddam
Volume 5, Issue 4 , 2002, , Pages 28-31
Abstract
Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients ...
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Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients and Methods: In this case-control study, 30 patients referred to skin clinics of Boo-Ali and Loghman Hakim hospitals in Tehran were compared with 30 individuals of similar sex and age who had not rosacea (Control group). Serologic tests for H. pylori infection (IgG and IgA), and also urea breath test were done. The results were compared using chi-square test with 95% confidence interval and P<0.05 was considered as significant. Results: No significant differences were seen between patients with rosacea and control group in having IgA (60% in case group, 40% in control group), IgG (76.6% in case group, 53.3% in control group) and positive breath test. Conclusion: More extensive research about possible relationship between H. pylori infection and rosacea is recommended.
R Yaghoobi; SJ Hashemi
Volume 2, Issue 2 , 1999, , Pages 10-19
Abstract
Helicobacter pylori is probably the commonest bacterial infection worldwide and is now accepted as the cause of gastritis, peptic ulcer, gastric carcinoma, and gastric lymphoma. In the last few years, besides the local gasteroduodenal tissue damage, an association between H.pylori and various extra-intestinal ...
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Helicobacter pylori is probably the commonest bacterial infection worldwide and is now accepted as the cause of gastritis, peptic ulcer, gastric carcinoma, and gastric lymphoma. In the last few years, besides the local gasteroduodenal tissue damage, an association between H.pylori and various extra-intestinal pathologies had been described. Recent studies have suggested that H.pylori infection may be associated with various skin disorders such as idiopathic chronic urticaria, Raynaud’s phenomenon, systemic sclerosis, rosacea, Sweet’s syndrome, Henoch-Schonlein purpura, psoriasis, and atopic dermatitis. In this paper we review the current knowledge on Helicobacter pylori infection and its relevance for skin diseases especially its clinical pathophysiological aspects.
