Tehranchinia Zohreh; Namazi Nastaran; Sarah Ershadi; Laya Rahbar Nikoukar; Gity Taheri
Volume 18, Issue 2 , 2015, , Pages 41-44
Abstract
Background: Androgenetic alopecia (AGA) is a non-scarring alopecia which consists of miniaturization of the terminal hair under the influence of androgens. Some scholars have reported an association between AGA and coronary artery disease (CAD), probably due to alterations in CAD risk factors. However, ...
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Background: Androgenetic alopecia (AGA) is a non-scarring alopecia which consists of miniaturization of the terminal hair under the influence of androgens. Some scholars have reported an association between AGA and coronary artery disease (CAD), probably due to alterations in CAD risk factors. However, this association is not supported by other studies, thus rendering the subject open to discussion.Methods: A total of 100 women were enrolled in this study: 50 diagnosed with AGA based on physical examination and 50 agematched controls. BMI as well as serum total cholesterol, highdensity lipoprotein (HDL-C), low-density lipoprotein (LDL-C), and triglyceride were measured.Results: The mean BMI was 25.3±3.5 kg/m2 in the AGA group and 24.2±3.4 kg/m2 in the control group (P=0.11). The mean level of triglyceride, total cholesterol, HDL-C, and LDL-C in the AGA group was 141.7±55.4 mg/dl, 194.9±35.8 mg/dl, 41.1±12.3 mg/ dl, and 129.7±32.6 mg/dl, respectively. These figures showed no significant difference in the control group (P=0.10)Conclusion: It seems that a diagnosis of AGA in female patients is not linked to increased serum lipids.
Saeedeh Farajzadeh; Soodabeh Zandi; Mohammad Mehdi Hayatbaksh Abbasi; Fahimeh Gadari; Armita Shahesmaeili; Behrooz Vares; Golamreza Hosseinpour; Iman Shojaei Baghini
Volume 14, Issue 3 , 2011, , Pages 81-85
Abstract
Background: The association between coronary artery disease and androgenic alopecia has been demonstrated, but few studies have focused on the mechanism of this association. The aim of this study was to evaluate the lipid profile in male pattern alopecia.Methods: In this case control study, 45 male patients ...
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Background: The association between coronary artery disease and androgenic alopecia has been demonstrated, but few studies have focused on the mechanism of this association. The aim of this study was to evaluate the lipid profile in male pattern alopecia.Methods: In this case control study, 45 male patients with androgenic alopecia who were aged from 20 to 50 years and 45 men with a normal hair status aged from 20 to 50 years were enrolled as the case and control groups, respectively. Lipid parameters including cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, lipoprotein (a), apolipoprotein A1, apolipoprotein B were measured in cases and controls.Results: A significant difference in serum lipoprotein (a) was observed between case and control groups (p< 0.001). We noted that 47.1 percent of the patients and 17.96% of the controls had a lipoprotein (a) level more than 30 mg/dl which is a critical level for coronary artery disease. There was no significant difference in other lipid parameters between two groups. The family history of androgenic alopecia and coronary heart disease was significantly higher in the cases than the controls.Conclusion: Considering the results of the study and the important role of lipoprotein (a) as a risk factor for atherosclerotic heart disease, we suggest that all men with a male pattern hair loss should be investigated for lipid indices, especially lipoprotein (a).
Farajzadeh Saeedeh; Esfandiarpour Iraj; Abbassi Mohammad Mehdi Hayatbatch; Moghaddam Sodaif Darvish; Hosseininasab Fatemeh
Volume 13, Issue 3 , 2010, , Pages 78-81
Abstract
Background: The correlation between coronary artery disease and androgenic alopecia has been demonstrated, but the mechanism of this association still remains to be cleared. Objective: To investigate lipid profile, as an indicator of coronary artery disease, in women with female pattern alopecia. Methods: ...
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Background: The correlation between coronary artery disease and androgenic alopecia has been demonstrated, but the mechanism of this association still remains to be cleared. Objective: To investigate lipid profile, as an indicator of coronary artery disease, in women with female pattern alopecia. Methods: Fifty one women with female pattern alopecia and thirty one healthy women with normal hair status were selected as the case and control groups, respectively. Lipid profile including cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, lipoprotein (a), apolipoprotein A1, and apolipoprotein B were measured in both groups. Results: The most important result of our study was a remarkably higher level of lipoprotein (a) in the case group. On the other hand, 55.3% of the patients and 16.7 % of the controls had lipoprotein (a) level >30 mg/dl, higher than the critical level for atherosclerosis. Conclusion: Lipid profile, especially lipoprotein (a), which is an important risk factor for coronary artery disease, should be investigated in women with androgenic alopecia. Those with disturbance in lipid profile should be referred to a cardiologist.