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1. The effect of metformin in the treatment of intractable and late onset acne: a comparison with oral isotretinoin

Behrangi Elham; Sadeghi Somayeh; Sadeghzadeh-Bazargan Afsaneh; Goodarzi Azadeh; Ghassemi Mohammadreza; Sepasgozar Saba; Rohaninasab Masoomeh

Volume 22, Issue 2 , 2019, , Pages 47-52

Abstract
  Background: Insulin resistance and increased insulin-like growth factor (IGF)-1 with consequent mammalian target of rapamycin complex (mTORC) 1 overexpression is responsible for acne pathogenesis, especially in women with polycystic ovary syndrome (PCOS). Metformin is shown to improve acne as an adjunct ...  Read More