@article { author = {Mohammad Ali, Mapar and Behrooz, Mali}, title = {The Comparison of Oral Ivermectin and Topical Lindane in the Treatment of Scabies}, journal = {Iranian Journal of Dermatology}, volume = {11}, number = {4}, pages = {147-150}, year = {2008}, publisher = {Iranian Society of Dermatology}, issn = {2717-0721}, eissn = {2717-0721}, doi = {}, abstract = {Background: Scabies is a common skin disease and a public health problem. The topical antiscabietics have a poor compliance. The aim of this study was to compare the efficacy of oral Ivermectin with topical Lindane solution in the treatment of scabies. Methods: This was a prospective comparative open study. Fifty seven patients were randomized in two groups. One group (32 patients) received 200µg/kg body weight of Ivermectin in two oral doses with a one-week interval, and the second group, (25 patients) received 2 consecutive weekly topical applications of Lindane. All patients were followed up for 2 weeks. Results: A single oral dose of Ivermectin cured 72% of patients and 91% of the patients were cured after the second dose. Two applications of Lindane with a one-week interval cured 92% of cases. Conclusion: Compared to topical Lindane in the treatment of scabies, Ivermectin was at least as effective as Lindane.}, keywords = {antiscabietics,Ivermectin,Lindane}, url = {https://www.iranjd.ir/article_98069.html}, eprint = {https://www.iranjd.ir/article_98069_28e152ac110fa54f03038ee8d9532948.pdf} }