TY - JOUR ID - 98435 TI - Histopathologic evaluation of Verrucous skin lesions in renal transplant recipients JO - Iranian Journal of Dermatology JA - IJD LA - en SN - AU - Iraji, F AU - Kiani, A AU - Shahidi, Sh AU - Vahabi, R AD - Y1 - 2001 PY - 2001 VL - 4 IS - 4 SP - 29 EP - 33 KW - Renal allograft recipient KW - Wart KW - histopathology DO - N2 - Background: Warts are common in renal allograft recipients (RAR) with reported incidence of 24% to 100%. These patients also demonstrate an accelerated malignant transformation of warts. Although in immunocompetent patients, the histology of common warts is quite predictable, this is not so in RAR. Objective: The purpose of this study was to evaluate the histopathologic findings of warty lesions in RAR. Patients and Methods: We examined 55 RARs for warty lesions. We took biopsy specimens from lesions that clinically appeared to be common warts and evaluated their histopathologic features. Results: Among 55 RARs, 17 cases (30.9%) had warty lesions, and among 50 biopsied lesions, 47 lesions (94%) showed changes of verruca vulgaris and only 3 Lesions (6%) showed warts with dysplasia. No malignant transformation was reported. All patients were under treatment with prednisolone, cyclosporin and azathioprine. The median time passed from transplantation was 49 months. Conclusion: We couldn’t find evidence of dysplasia or malignancy in most verrucous lesions of RAR. This maybe due to relatively short time passed from transplantation in our patients. UR - https://www.iranjd.ir/article_98435.html L1 - https://www.iranjd.ir/article_98435_6c797231eefc848ccf1511f607cd6a32.pdf ER -