Iranian Journal of Dermatology

Vol. 15, No. 60, Summer 2012
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Diagnostic pitfalls of pilomatricoma on fine needle aspiration cytology
Veena Gupta, Nisha Marwah, Promil Jain, Shivani Dua, Sumiti Gupta, Rajeev Sen

Contact Info: Department of Pathology, PGIMS, Rohtak, Haryana, India, Email:

Date Received: 2012 / May / 26 Date Revised: 2012 / May / 26 Date Accepted: 2012 / Jul / 02

Pilomatricoma is a benign skin adnexal tumour usually seen in the head and neck region of children and young adults. It is underrecognized on cytology, resulting in the overdiagnosis of malignancy. We bring forth a case report of a slow growing nodular swelling in a 10-year-old female child, which was misdiagnosed on Fine Needle Aspiration Cytology (FNAC) as a malignant neoplasm and found to be pilomatricoma histopathologically. Nodular lesions of pilomatricoma, which are predominantly composed of basaloid cells and devoid of other diagnostic features, lead to a false diagnosis of malignancy. To avoid misdiagnosis, pilomatricoma should be considered in differential diagnosis when primitive appearing cells are aspirated in slow growing subcutaneous nodules. Cytomorphological features of pilomatricoma and major pitfalls in diagnosis are also being discussed.

Keywords: adnexal tumour, fine needle aspiration cytology, pilomatricoma

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