Iranian Journal of Dermatology

Vol. 15, No. 62, Winter 2012
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Diffuse normolipemic plane xanthomas in a healthy male infant
Maryam Emad, Fatemeh Sari Aslani, Nasrin Saki, Dorna Motevalli, Forugh Saki

Contact Info: Nasrin Saki, MD Skin Research Center, Dermatology Department, Shiraz University of Medical Sciences, Shiraz, Iran Email:

Date Received: 2011 / Aug / 14 Date Revised: 2011 / Aug / 14 Date Accepted: 2012 / Sep / 05

Diffuse normolipemic plane xanthoma is characterized by the
presence of yellowish-orange plaques on the eyelids, neck, upper
trunk, buttocks and flexural surfaces of the extremities in patients
with a normal lipid profile. It mainly affects adults of both sexes.
Diffuse normolipemic plane xanthomas are usually associated
with reticuloendothelial system disorders, such as multiple
myeloma and monoclonal gammopathies. We report a case of
diffuse plane xanthomas in an otherwise healthy 1-year-old male
infant who developed multiple disseminated non-inflammatory
yellowish-orange macules and patches that were not associated
with any other symptoms..

Keywords: diffuse plane xanthoma, histiocytosis, infantile, serum lipid

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