Iranian Journal of Dermatology

Vol. 16, No. 66, Winter 2013
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Exfoliative dermatitis: a study from the Northeast of Iran
Mohammad Javad Yazdanpanah, Reza Nourbakhsh, Fakhrozaman Pezeshkpoor, Mahnaz Banihashemi, Jamshid Baradaran-Moghadam

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Date Received: 2014 / Apr / 12 Date Revised: 2014 / Apr / 12 Date Accepted: 2014 / Apr / 12

Background: Exfoliative dermatitis is a rare disorder with several
etiologic factors. The frequency of different etiologies varies in
the medical literatures. The purpose of this study was to reveal
the demographic characteristic and etiologies of exfoliative
dermatitis in our department.
Method: We reviewed the records of the patients who were
admitted to the dermatology ward of Ghaem Hospital, Mashhad,
Iran, with a diagnosis of exfoliative dermatitis in a twenty-year
period (1982-2002). Age, gender, the cause of exfoliative dermatitis,
and the most probable drug cause were studied.
Result: Fifty-nine cases were included in the study. Male-female
ratio was 1.27:1. The mean age of the patients was 50.11±19.37.
The most common causes were psoriasis (40.7%), drugs (18.6%)
and lymphoma (18.6%). The most common drugs that caused
exfoliative dermatitis were co-trimoxazole (27.27%), carbamazepine
(18.18%), and gold salts (18.18%).
Conclusion: The most frequent of underlying cause of exfoliative
dermatitis in our series was psoriasis. Co-trimoxazole was the
most common drug that caused exfoliative dermatitis.

Keywords: erythroderma, etiology, exfoliative dermatitis

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