Iranian Journal of Dermatology

Vol. 19, No. 78, winter 2016
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Generalized granuloma annulare in association with breast carcinoma
Mahnaz Banihashemi, Mohammad Javad Yazdanpanah, Soleiman Nouri, Sarah Hashemzadeh

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Date Received: 2016 / Aug / 23 Date Revised: 2016 / Aug / 23 Date Accepted: 2016 / Oct / 25

The association of granuloma annulare and some neoplasms is controversial. However, there is an increase in the number of case reports and relevant studies supporting the concept
of granuloma annulare being associated with certain types of hematologic neoplasms and solid tumors.
Herein, we describe a 54-year-old woman with a 20-month history of generalized annular lesions that did not respond to conventional treatment and was followed by breast cancer. Only two cases of granuloma annulare and breast cancer have been reported so far in the literature. We believe that these cases emphasize on considering granuloma annulare as a possible paraneoplastic dermatoses.

Keywords: breast cancer, granuloma annulare, neoplasm

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