Balighi Kamran; Lajevardi Vahideh; Moeineddin Fatemeh; Naraghi Zahra; Irvani Masoud
Volume 11, Issue 1 , 2008, , Pages 38-41
Abstract
A 15-year-old boy presented with several months history of bilateral axillary lymph adenopathies which were ulcerated subsequently. He had received anti-tuberculosis therapy for more than six months based on suspicious diagnosis of scrofuloderma. Histopathologic examination confirmed the diagnosis of ...
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A 15-year-old boy presented with several months history of bilateral axillary lymph adenopathies which were ulcerated subsequently. He had received anti-tuberculosis therapy for more than six months based on suspicious diagnosis of scrofuloderma. Histopathologic examination confirmed the diagnosis of specific lesions of Hodgkin’s disease. These lesions were probably metastatic due to retrograde lymphatic spread from his axillary lymph nodes, as this way is the most common mode of Hodgkin’s disease spreading to the skin. The patient received chemotherapy regimen for Hodgkin’s disease and ulcers resolved remarkably.
Balighi Kamran; Lajevardi Vahideh; Moeineddin Fatemeh; Ghiassi Maryam; Arami Shabnam; Nikoo Azita; Mahdavi-nia Mostafa
Volume 10, Issue 4 , 2007, , Pages 338-344
Abstract
Atrichia with papular lesions (APL) is a rare, autosomal recessive syndrome with total alopecia in which mutations in the hairless gene have been shown to underlie the phenotype. We report here three cases, two 16 and 18 years old cousins and a 15 year-old-girl with a history of shedding of scalp, eyebrow ...
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Atrichia with papular lesions (APL) is a rare, autosomal recessive syndrome with total alopecia in which mutations in the hairless gene have been shown to underlie the phenotype. We report here three cases, two 16 and 18 years old cousins and a 15 year-old-girl with a history of shedding of scalp, eyebrow and eye lashes in infancy. Later in life they developed numerous erythematous papules on their limbs predominantly on the knees and elbows. According to their history, clinical presentation and pathologic findings, diagnosis of atrichia with papular lesions (APL) with some different features was postulated. Comparing to the known cases of APL with scalp, facial and truncal lesions, the cases presented here do not show such lesions in these sites.
Emadi Seyed Naser; Sorush Mohammadreza; Moeineddin Fatemeh; Davudi Seyed Masoud; Jalalian Hamid Reza; Ardakani Mohammadreza Khodaeeyani
Volume 10, Issue 4 , 2007, , Pages 345-352
Abstract
Sulphur Mustard is a potent chemical warfare agent that was widely used during first world war and Iran Iraq conflict. Over 100,000 Iranians were injured by sulphur mustard and one-third is of them were suffering from late effects until today. This vesicant agent has a lot of acute and chronic destructive ...
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Sulphur Mustard is a potent chemical warfare agent that was widely used during first world war and Iran Iraq conflict. Over 100,000 Iranians were injured by sulphur mustard and one-third is of them were suffering from late effects until today. This vesicant agent has a lot of acute and chronic destructive effects on the skin, eye and respiratory system. Sulphur mustard via the alkylations of several cellular proteins (structural, cytoplasmic and enzymes) and cell nuclei, produce several toxic, mutagenic and carcinogenic effects on epidermis, dermis, dermal appendages and hypodermis. We report a 41-year-old man who was poisoned with sulphur mustard in 1988.After exposure he developed severe skin blisters on upper trunk, posterior aspect of both hands and genitalia along with ocular and respiratory complications. He also had atrophy, pigmentation and vascular changes on skin of penis with pigmentation, atrophy and related findings in histopathologic studies, so the diagnosis of "sulphur mustard induced poikiloderma" was postulated. The absence of any complication on palms despite of their recurrent exposure to sulphur mustard is another remarkable finding in this case. It has been suggested that palms can act as a transport vector of sulphur mustard to other sites of skin.
