Ehsani Amir Hooshang; Noormohammadpoor Pedram; Sadeghinia Ali; Hemmati Sara; Ahmadi Maedeh; Sotoudeh Sara; Azizpour Arghavan; Nasimi Maryam
Volume 20, Issue 4 , 2017, , Pages 118-121
Abstract
Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional ...
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Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional study was conducted on 650 BCC patients, who were referred to the dermatology tumor clinic of Razi hospital from 2008 to 2012 with confirmed biopsy results of BCC. Patient characteristics including age, sex, relevant history and physical examination and tumor characteristics such as location and pathological subtypes were recorded.Results: The prevalence of lower limb BCC was 1.53% with the mean age of 69.5 years and a male to female ratio of 2.33:1. Of 10 cases with BCC on the lower extremities, 6 were on the legs, 3 on the thighs and 1 on the foot. The most frequent pathological type was nodular and constant UV exposure was the most important risk factor (60%). Other underlying factors were chemical exposure, chronic ulcer and history of radiation.Conclusion: BCC of the lower limbs is more prevalent in men compared with women. Moreover, UV exposure is the most important risk factor for BCC. On the other hand, factors like ulcers, radiation and chemical exposure have to be further considered.
Ehsani Amirhoushang; Mortazavi Hossein; Azizpour Arghavan; Ansari Mahsa; Teimori Edris; Goodarzi Azadeh; Rahbar Ziba; Aryanian Zeinab
Volume 17, Issue 2 , 2014, , Pages 63-67
Abstract
Background: Although most cases of drug eruptions are mildand self-limited and are relieved after discontinuation of theresponsible drugs, statistics of life threatening outcomes shouldbe kept in mind. Moreover, it is important to identify the mostcommon age and sex groups, and the most vulnerable groupsin ...
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Background: Although most cases of drug eruptions are mildand self-limited and are relieved after discontinuation of theresponsible drugs, statistics of life threatening outcomes shouldbe kept in mind. Moreover, it is important to identify the mostcommon age and sex groups, and the most vulnerable groupsin any area related to offending drugs. Thus, we collected thebasic information of patients with skin drug reactions who wereadmitted to Razi Hospital, Tehran, Iran, during 2010-2012 (18months).Method: In this study, all patients with a diagnosis of drugreactions who were admitted to Razi Hospital, Tehran, Iran,during 2010-2012 (18 months) were enrolled. The types of drugsand skin reaction manifestations were reported.Result: One hundred and thirty one patients were admitted witha diagnosis of drug reactions. The mean age of the participantswas 40 years. Forty one patients were male (31.3%) and 90 werefemale (68.3%). Antibiotics and anticonvulsants were the mostcommon drugs associated with reactions. Carbamazepine wasthe most common drug that caused reactions (21 cases, 17.4%)followed by penicillin (20 cases, 16.5%), and lamotrigine (16 cases,13.2%). Morbilliform rash (40 cases, 30.5%), erythroderma (18cases, 13.7%), and urticaria/angioedema (14 cases, 10.7%) werethe most common patterns of skin involvement.Conclusion: The results of our study are consistent with the resultsof other studies. It is recommended that drugs that commonlycause adverse reactions be prescribed with more precautionin females aged 20-40 years, and if possible, be replaced withappropriate drugs. Moreover, it is recommended that patients whoare allergic to these drugs carry a certain card that demonstratestheir sensitivity.