ZB Mousavi; M Meshki; A Hemmati; MS Veisi; R Rafiei
Volume 9, Issue 3 , 2006, , Pages 260-263
Abstract
Background and aim: Improvement of wound healing in normal subjects and in chronic ulcers has been always desired. The availablity and acceptability of herbal medicine led us to study the effect of topical 10% mucilage of quince seed in human skin.Materials and Methods: This double-blind clinical trial ...
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Background and aim: Improvement of wound healing in normal subjects and in chronic ulcers has been always desired. The availablity and acceptability of herbal medicine led us to study the effect of topical 10% mucilage of quince seed in human skin.Materials and Methods: This double-blind clinical trial has been conducted on 34 patients referring to Imam Hospital, clinic of dermatology for elective surgery or excisional biopsy of benign lesions. The patients were divided into 3 groups and their lesions were treated with either 10% quince mucilage or eucerin or left untreated. The wound surface was measured on the days 0, 3, 5, 7, 14 and 20. The data were analyzed by ANOVA.Results: The mean duration of complete healing was 10.72 days in quince mucilage, 15.62 days in eucerin, and 16.7 days in untreated group (P<0.05).Conclusion:10% quince mucilage ointment improved wound healing. Further and larger studies are needed to evaluate the quince mucilage effect and its possible application for patients suffering form chronic ulcers.
R Yaghoobi; N Sina; N Emad Mostofi; R Rafiei
Volume 8, suppl , 2004, , Pages 39-46
Abstract
Pretibial epidermolysis bullosa is a rare variant of hereditary epidermolysis bullosa characterized by the delayed onset of lesions and their localization. We present two cases, a 35-year-old woman and a 21-year-old man. They clinically had pruritus, nodular prurigo-like or lichenified lesions, violaceous ...
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Pretibial epidermolysis bullosa is a rare variant of hereditary epidermolysis bullosa characterized by the delayed onset of lesions and their localization. We present two cases, a 35-year-old woman and a 21-year-old man. They clinically had pruritus, nodular prurigo-like or lichenified lesions, violaceous scarring, milia, nail dystrophy and in one case albopapuloid lesions on the trunk. Physical signs of disease were first noticed between 3 and 9 years of age. Histologic examination showed a subepidermal blister with milia formation, and a mild mixed inflammatory infiltrate. These patients represent an nusual, poorly recognized form of dystrophic epidermolysis bullosa with features that resemble a variety of acquired dermatoses.
R Yaghoobi; R Rafiei; F Savad Dar; SM Latifi
Volume 5, Issue 3 , 2002, , Pages 7-14
Abstract
Background: Malignant melanoma is the leading cause of death among skin cancers in western countries. However, the incidence, histologic subtypes, and tumor behaviors are quite different in Asians and western populations. Objective: This study was designed to survey the clinicopathological aspects of ...
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Background: Malignant melanoma is the leading cause of death among skin cancers in western countries. However, the incidence, histologic subtypes, and tumor behaviors are quite different in Asians and western populations. Objective: This study was designed to survey the clinicopathological aspects of malignant melanoma among Khouzestan people. Patients and Methods: In a retrospective study 62 patients (28 women, mean age 53.80±14.1, and 34 men, mean age 55.9±15.8) were diagnosed as melanoma in Khouzestan province, southwest of Iran during 1990-2000. The analyzed data included sex, age at diagnosis, location and histologic subtypes. Results: Malignant melanoma was found to be more common in men than women, in the approximate ratio of 5 to 4. From 62 cases of malignant melanoma, 59.67% were cutaneous, 19.35% metastatic in lymph nodes, 11.29% ocular, 4.83% gastrointestinal tract, 3.22% mucosal, and 1.61% inner ear and mastoid. The majority of cases were unclassified malignant melanoma (30.64%), followed by nodular melanoma (27.41%), metastatic malignant melanoma (24.19%), acral lentiginous melanoma (12.9%), and lentigo maligna melanoma (4.84%), respectively. Conclusion: Although malignant melanoma is a rare tumor in Khouzestan, further studied are necessary to analyze present and future trends of melanoma, accurately. Ongoing and new prevention and control strategies may be mandatory to curtail the melanoma outbreak.