SM Davoudi; P Rostami; SN Emadi; B Sadr; E Khabiri
Volume 9, Issue 3 , 2006, , Pages 217-220
Abstract
Background and aim: Paederus dermatitis is an acute self-healing blistering disease caused by an insect from the genus Paederus species. Although it is a self-limited disease, it can cause disablement and suffering. The objective of this study was to investigate the efficacy of fluocinolone cream, triclocarban(TCC) ...
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Background and aim: Paederus dermatitis is an acute self-healing blistering disease caused by an insect from the genus Paederus species. Although it is a self-limited disease, it can cause disablement and suffering. The objective of this study was to investigate the efficacy of fluocinolone cream, triclocarban(TCC) soap and betamethasone lotion in comparison with placebo in the treatment of paederus dermatitis.Materials and Methods: This study was a randomized single blind placebo controlled trial which was performed in Behshahr hospitals during a period of two months. Seventy-seven patients with paederus dermatitis were randomized to treatment with fluocinolone cream, TCC soap, betamethansone lotion or a placebo. The conditon of each patient was checked three times; i.e., on their first, fifth and twelfth day of receiving treatment. Finally, depending on their response to treatment, they were divided into two groups, those who fully recovered and those failing to recover.Results: Of the 77 patients studied, 18 were treated with a placebo, 17 with betamethasone lotion, 24 with fluocinolone cream and 17 with TCC soap. Complete recovery at the end of treatment was fluocinolone 100% , betamethasone 100%, TCC 58.8% and placebo 33.3%. Significant differences were observed between two first groups and the placebo group (P=0.0001) but no significant difference was observed between TCC soap and placebo.Conclusion: Topical corticosteroids displayed a relative and significant improvement in paederus dermatitis.
Y Panahi; SM Davoudi; S Keshavarz; R Sarhang Nejad; A Tajic; MM Naghi Zadeh
Volume 9, Issue 2 , 2006, , Pages 114-121
Abstract
Background and aim: Chronic skin lesions are common late complications of sulfur mustard intoxication which would result in numerous complaints including pruritus, skin dryness and burn feeling. In chemical warfare injured veterans, pruritus is the most common complaint in chronic status with significant ...
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Background and aim: Chronic skin lesions are common late complications of sulfur mustard intoxication which would result in numerous complaints including pruritus, skin dryness and burn feeling. In chemical warfare injured veterans, pruritus is the most common complaint in chronic status with significant effects on patient's quality of life. This study has evaluated efficacy of topical phenol 1% and menthol 1% combination in treatment of pruritus in chemical warfare injured veterans in comparison with placebo.Materials and Methods: This randomized double blind clinical trial was done on chemical warfare injured veterans with mustard gas induced pruritus. Eighty patients were randomly divided to 2 equal groups, one group treated with phenol 1% and menthol 1% combination and other group with placebo for 6 weeks and the therapeutic effects were evaluated according to pruritus scores.Results: Pruritus score was significantly reduced in active group compared to placebo group (P=0.026).Conclusion: Phenol 1% and menthol 1% combination has significant therapeutic effect for mustard gas induced pruritus in chemical warfare injured veterans.
SM Davoudi; AA Karimi Zarchi; S Ghafouri Manesh; AR Firooz; M Nasiri Kashani; Y Dowlati
Volume 8, Issue 3 , 2005, , Pages 166-170
Abstract
Background: Eczema is one of the most widely spread inflammatory skin disorders contact dermatitis is an eczematous dermatitis that is produced as a result of contact with a substance in the environment. The substance can act as an irritant or allergen. Every country has allergen particular to itself. ...
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Background: Eczema is one of the most widely spread inflammatory skin disorders contact dermatitis is an eczematous dermatitis that is produced as a result of contact with a substance in the environment. The substance can act as an irritant or allergen. Every country has allergen particular to itself. Objective: Determining the frequency of skin allergens in patients with contact dermatitis in Tehran. Patients and Methods: In this cross-sectional descriptive study, all the data about the patients with chronic contact dermatitis who were visited in a dermatology clinic in Tehran from the year 1993 to 2003 and patch tested with 23 allergens of European standard series (ESS) were analyzed. Results: In this study 222 patients were surveyed. The mean age of the patients was 33.5 years (SD=13.8). 66.5% of the patients were female. The most common site of involvement (49%) was their hands. The mean duration of the disease was 54 months (SD=62). Clinical diagnosis included: 59% allergic contact dermatitis, 24% irritant dermatitis, 10% atopic dermatitis, and 7% other types of dermatitis. 145 (65.3%) of them had at least one positive reaction. The most common allergens were: Nickle sulfate 22.6%, cobalt chloride 14.5%, and fragrance mix 13.6%. Conclusion: Nickel was the most common contact allergen among the patients surveyed.
