Maryam Akhyani; Cheyda Chams-Davatchi; Zahra Safai Naraghi; Maryam Daneshpazhooh; Siavash Toosi; Masoud Asgari; Fatemeh Malek Hami
Volume 10, Issue 3 , 2007, , Pages 194-202
Abstract
Background and aim: Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim ...
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Background and aim: Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim was to evaluate involvement of the female genital tract and cervicovaginal Papanicolaou (Pap) smears in PV.Materials and methods: The study included 77 patients with PV visited from April 2005 to February 2007. Each patient was subjected to gynecological examination and cervicovaginal Pap smear.Results: The mean age of patients was 44.7±13 years. Genital lesions were observed in 39 patients (50.6%). Labia minor was involved in 36 patients (92.3%), while labia major in 11 (28.2%), vagina in 14 (35.8%), and cervix in six (15.3%). Cervicovaginal smears of 20 patients (25.9%) showed PV. Among 72 satisfactory smears, cervical Pap smears were normal in 25 patients (34.7%), inflammatory in 43 patients (59.7%), and dysplastic (low-grade cervical intra-epithelial neoplasia [CIN I]) in four patients (5.5%). In 2 of these patients, Pap smears was normal repeated when patients were in remission.Conclusion: Involvement of the female genital tract might not be as infrequent as was previously thought and it is probably the second most common mucosal site of PV after oral mucosa. Genital lesions may be missed and the need for thorough pelvic examination should not be overlooked.
Mostafa Mirshams Shahshahani; Nafiseh Esmaili; Pedram Mehryan; Amir Houshang Ehsani; Siavash Toosi
Volume 10, Issue 1 , 2007, , Pages 2-8
Abstract
Background and aim : The clinical management of verrucae vulgaris is often challenging and no treatment is always effective. Early studies have suggested that pulsed-dye laser (PDL) may be highly effective in the treatment of verrucae through obliteration of dilated vessels in papillary dermis. The objective ...
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Background and aim : The clinical management of verrucae vulgaris is often challenging and no treatment is always effective. Early studies have suggested that pulsed-dye laser (PDL) may be highly effective in the treatment of verrucae through obliteration of dilated vessels in papillary dermis. The objective of this study was to compare safety and efficacy of 585 nm with 595 nm PDL in the treatment of warts.Materials and methods: The randomized controlled trial was done on forty patients with warts referred to Razi Hospital in Tehran. Almost symmetrically distributed warts were randomized to receive PDL 585 nm or 595 nm on their left or right side and a similar lesion with respect to size, thickness and location was not treated as control. Each patient was treated in three sessions at three- week intervals. Warts were individually examined at the time of each treatment session and their size and adverse effects of treatment recorded. Complete response was defined as complete disappearance of lesions.Results: Thirty-six patients completed the trial. The mean size of the lesions before the treatment were 19.7±13.2 mm2 in PDL 585 nm group and 21.7±15.4 mm2 in PDL 595 nm group. After the last treatment the mean reduction in size of warts were 18.1±12.3 mm2 and 18.1±11.2 mm2 and the lesions cleared in 27 (75%) and 25 (69%) patients in PDL 585 nm and PDL595 nm groups, respectively (P value =0.83). Variable degrees of purpura and pain were observed in all patients which was classified as severe in 15 and 16 cases in PDL 585 nm group and 19 and 18 cases in PDL 595 nm group, respectively (P=0.8).Conclusion: The PDL is an effective treatment for verrucae vulgaris and there are no statistically significant differences between 585 nm and 595 nm with respect of their efficacy and adverse effects.
Suzan Kavusi; Zahra Safaii Naraghi; Ali Naser Tork; Siavash Toosi
Volume 9, suppl.1 , 2006, , Pages 8-8
Abstract
Spindle cell hemangioma is a benign vascular tumor presenting as multifocal red or bluish nodules on the distal limbs. We present a 57-year-old woman with five years history of multiple, soft, violaceous nodules on her hands. Pathologic study indicated spindle cell hemangioma.
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Spindle cell hemangioma is a benign vascular tumor presenting as multifocal red or bluish nodules on the distal limbs. We present a 57-year-old woman with five years history of multiple, soft, violaceous nodules on her hands. Pathologic study indicated spindle cell hemangioma.