Soori Tahereh; Esmaeili Nafiseh; Najmeh Rajabi; Amir Houshang Ehsani
Volume 18, Issue 2 , 2015, , Pages 56-60
Abstract
Background and Objective: Genital warts, the most common sexually transmitted disease (STD), are caused by human papillomavirus (HPV). Few studies have been performed on Iranian women with genital warts or cervix cancer but there isno documented data about genital warts and HPV genotyping in Iranian ...
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Background and Objective: Genital warts, the most common sexually transmitted disease (STD), are caused by human papillomavirus (HPV). Few studies have been performed on Iranian women with genital warts or cervix cancer but there isno documented data about genital warts and HPV genotyping in Iranian men. In this study, we determined HPV genotypesin 108 male and females with anogenital warts in an STD clinic in Tehran.Methods: In this cross sectional study, HPV genotypes were determined by the PCR method in 108 males and females withanogenital warts who were visited at an STD clinic in Tehran within January–June 2012. Age, sex, number of sexual partners,education level, and marital status were recorded in the questionnaires.Results: We determined HPV genotypes in 108 patients including 36 men and 72 women. The mean age of the patients was 31.5±12.3 years. The most common type was type 6 (62%). Other common genotypes were 11 (28.7%), 18 (15.7%), 16 (14.8%), 31 (4.6%), 33 (0.9%), 51 (0.9%), 56 (0.9%), and 66 (0.09%). We found that genotypes 16 (P=0.003) and 31 (P=0.013) were more prevalent in the patients with a higher number of sexual partners. In addition, there was a statistically significant association between the number of sexual partners and multi type HPV infection (P=0.045). Genotypes 16 (P=0.036) and 11 (P=0.039) were significantly associated with the female gender.Conclusion: Our results showed that HPV 6 was the most prevalent HPV type followed by HPV 11, 18, and 16.
Mostafa Mirshams Shahshahani; Mahmood Razzaghi; Amir Houshang Ehsani; Pedram Normohamadpour; Zahra Naraghi; Kambiz Kamyab; Sara Sabouri Rad
Volume 14, Issue 1 , 2011, , Pages 1-5
Abstract
Background: Surgery is the most frequent treatment modality for basal cell carcinoma but in spite of its high cure rate, the frequency of incomplete excision varies widely (0.7-50%) among dermatologic centers. Our case series was designed to determine the frequency of incompletely excised basal cell ...
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Background: Surgery is the most frequent treatment modality for basal cell carcinoma but in spite of its high cure rate, the frequency of incomplete excision varies widely (0.7-50%) among dermatologic centers. Our case series was designed to determine the frequency of incompletely excised basal cell carcinoma and the related risk factors. Methods: A total of 1424 basal cell carcinoma (1040 patients) lesions which were excised in Razi Dermatology Hospital of Tehran from 2006 to 2008 were evaluated in this case series and their findings were analyzed with SPSS software. Results: Incidence of incomplete excision was 12% and involvement of the deep margin was observed in 54% of these lesions. Factors related to incomplete excision were infiltrative, morpheic and micronodular subtypes, lesions larger than 20 mm, those repaired by skin grafts and those that received local anesthesia. There was no statistically significant difference in age, sex, site of lesions and childhood history of radiotherapy for tinea capitis. Conclusion: Recognizing the risk factors related to incomplete excision of BCCs would help us consider a wider excision margin for high risk tumors.
Amir Houshang Ehsani; Pedram Normohammadpour; Shahrbanoo Kheirkhah Sabetghadam
Volume 14, Issue 1 , 2011, , Pages 40-41
Nafiseh Esmaily; Amirhooshang Ehsani; Pedram Noormohammadpour; Iman Baiagouy; Shima Sayanjali
Volume 13, Issue 4 , 2010, , Pages 118-121
Abstract
Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease with a high rate of morbidity and mortality without treatment. Until now, treatments consist mostly of the use of corticosteroid and immunosuppressive drugs. Optimum dosage for corticosteroid therapy is yet to be determined. ...
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Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease with a high rate of morbidity and mortality without treatment. Until now, treatments consist mostly of the use of corticosteroid and immunosuppressive drugs. Optimum dosage for corticosteroid therapy is yet to be determined. The aim of the present study was to clear whether different initial corticosteroid therapeutic dosages change the recurrence rate of the disease.Methods: Patients hospitalized with confirmed PV from 2000 to 2006 were enrolled if they received systemic corticosteroids without any adjuvant therapy for no more than three weeks when hospitalized, received their first treatment in the period of the study and were followed for at least two years in the PV clinic of Razi Hospital periodically. Initial steroid dosage as well as the number and type of the recurrence(s) were documented and analyzed.Results: A total of 62 patients with a mean age of 46.8 (± 15.9) were enrolled. Twenty-one patients were female (33.9%) and 41 patients (66.1%) were male. According to the initial dose of systemic corticosteroid, patients were divided into two groups: group A included patients treated with less than 2mg/kg (10 patients or 16.1%) while group B included patients treated with 2mg/kg systemic steroids (52 patients or 83.9%). There was no significant difference in the recurrence rate between the two groups. Recurrence rate was 40% in group A and 51% in group B (P>0.05). According to the type of recurrence, there was a significant difference between the two groups; in group A, the first recurrence was major in 33% of the patients while in group B, this rate was about 28.8% (P<0.05).Conclusion: According to the present study, initial therapeutic dosage did not influence the recurrence rate although the type of recurrence was influenced. Patients treated with higher initial steroid dosages experienced their first episode as a minor recurrence while patients treated with lower initial steroid dosages experienced major recurrences with a higher probability as their first episode.
Amirhooshang Ehsani; Pedram Noormohammadpour; Kamran Balighi; Narges Ghandi; Parisa Dabirvaziri; Sahar Azizahari
Volume 12, Issue 3 , 2009, , Pages 74-78
Abstract
Background: Ingrown toe nail (IGTN) is a painful condition in which the distal-lateral corner of the nail grows into its surrounding soft tissue leading to inflammation and infection. Failure of conservative therapy is an indication for surgical interventions. The aim of this study is to compare matricectomy ...
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Background: Ingrown toe nail (IGTN) is a painful condition in which the distal-lateral corner of the nail grows into its surrounding soft tissue leading to inflammation and infection. Failure of conservative therapy is an indication for surgical interventions. The aim of this study is to compare matricectomy by curettage with chemical matricectomy with phenol 88% in terms of post procedure remission and complications.Methods: A number of 18 patients with IGTN were selected and divided randomly into 9-subject groups. The first group underwent matricectomy by curettage and the second underwent chemical matricectomy with phenol 88%. Patients were assessed after 2, 7 days and 1, 4 months after surgery for pain, oozing, soft tissue inflammation, cellulitis or purulent discharge and recurrence in both of the groups and the results were statistically compared.Results: On the third post procedure day, pain and oozing discharge occurred less in curettage group with significant difference (P = 0.016 and 0.009). In our next visit, one week after procedure, there was no significant difference in recovery and post procedure complications (P = 0.475). In our visit, 4 weeks after procedure, all cases in both groups were completely healed for all parameters and no complication was found.Conclusion: Curettage partial matricectomy is superior to phenol matricectomy in achieving earlier release of post procedure symptoms and complete recovery.
Amir Hooshang Ehsani; Katrin Kiavash
Volume 10, Suppl.2 , 2007, , Pages 1-1
Abstract
Pachyonychia congenital (PC) is a rare genodermatosis affecting the nails, skin, oral mucosae, larynx, hair, and teeth. General clinical presentation includes thickening of finger and toenails, painful plantar keratoderma, hyperhidrosis, oral leukokeratosis, follicular keratosis, palmar keratoderma, ...
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Pachyonychia congenital (PC) is a rare genodermatosis affecting the nails, skin, oral mucosae, larynx, hair, and teeth. General clinical presentation includes thickening of finger and toenails, painful plantar keratoderma, hyperhidrosis, oral leukokeratosis, follicular keratosis, palmar keratoderma, cutaneous cysts, hoarseness, twisted hair and prenatal or natal teeth. Clinically, PC is divided into 4 distinct subtypes. Here, we present a three-year-old girl with PC type II.
Amirhushang Ehsani; Fatemeh Moeineddin; Ahmadreza Rajaee
Volume 10, Suppl.2 , 2007, , Pages 8-8
Abstract
A 10-month-old female presented with severe progressive wedge-shaped thickening and discoloration of all twenty nails. Further evaluations revealed palmoplantar keratoderma along with recurrent acral blisters causing residual crusted ulcers which were present during the past six months. Other findings ...
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A 10-month-old female presented with severe progressive wedge-shaped thickening and discoloration of all twenty nails. Further evaluations revealed palmoplantar keratoderma along with recurrent acral blisters causing residual crusted ulcers which were present during the past six months. Other findings include scalp kinky hair and dental caries. Patient history was remarkable for natal teeth and similar skin blisters in her older brother since his infancy.The patient's clinical presentation and history are consistent with pachyonychia congenita syndrome showing concomitant features of both subtypes 1 and 2, probably due to a new mutation in the responsible gene.
Mostafa Mirshams Shahshahani; Nafiseh Esmaili; Pedram Mehryan; Amir Houshang Ehsani; Siavash Toosi
Volume 10, Issue 1 , 2007, , Pages 2-8
Abstract
Background and aim : The clinical management of verrucae vulgaris is often challenging and no treatment is always effective. Early studies have suggested that pulsed-dye laser (PDL) may be highly effective in the treatment of verrucae through obliteration of dilated vessels in papillary dermis. The objective ...
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Background and aim : The clinical management of verrucae vulgaris is often challenging and no treatment is always effective. Early studies have suggested that pulsed-dye laser (PDL) may be highly effective in the treatment of verrucae through obliteration of dilated vessels in papillary dermis. The objective of this study was to compare safety and efficacy of 585 nm with 595 nm PDL in the treatment of warts.Materials and methods: The randomized controlled trial was done on forty patients with warts referred to Razi Hospital in Tehran. Almost symmetrically distributed warts were randomized to receive PDL 585 nm or 595 nm on their left or right side and a similar lesion with respect to size, thickness and location was not treated as control. Each patient was treated in three sessions at three- week intervals. Warts were individually examined at the time of each treatment session and their size and adverse effects of treatment recorded. Complete response was defined as complete disappearance of lesions.Results: Thirty-six patients completed the trial. The mean size of the lesions before the treatment were 19.7±13.2 mm2 in PDL 585 nm group and 21.7±15.4 mm2 in PDL 595 nm group. After the last treatment the mean reduction in size of warts were 18.1±12.3 mm2 and 18.1±11.2 mm2 and the lesions cleared in 27 (75%) and 25 (69%) patients in PDL 585 nm and PDL595 nm groups, respectively (P value =0.83). Variable degrees of purpura and pain were observed in all patients which was classified as severe in 15 and 16 cases in PDL 585 nm group and 19 and 18 cases in PDL 595 nm group, respectively (P=0.8).Conclusion: The PDL is an effective treatment for verrucae vulgaris and there are no statistically significant differences between 585 nm and 595 nm with respect of their efficacy and adverse effects.
Mahboobeh-sadat Hosseini; Amir Hushang Ehsani; Vahideh-sadat Lajvardi; Maryam Ghiasi; Pedram Mehryan; Shideh Yazdanian; Ali Naser Tork; Reza Mahmood Robati
Volume 10, Issue 1 , 2007, , Pages 60-73
Abstract
Cutaneous manifestations of thyroid diseases can be divided into three groups:1-Specific lesions such as the thyroglossal duct cyst and cutaneous metastases form thyroid malignancy.2-Nonspecific signs secondary to thyroid hormone imbalance.3-Cutaneous signs of associated systemic and dermatologic disorders.This ...
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Cutaneous manifestations of thyroid diseases can be divided into three groups:1-Specific lesions such as the thyroglossal duct cyst and cutaneous metastases form thyroid malignancy.2-Nonspecific signs secondary to thyroid hormone imbalance.3-Cutaneous signs of associated systemic and dermatologic disorders.This review constitutes a summary and update of the cutaneous manifestations of thyroid diseases.
Amir Houshang Ehsani; Mahboubeh Sadat Hosseini; Alireza Mir Esmaili; Reza Nemati
Volume 9, Issue 4 , 2006, , Pages 355-359
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific ...
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Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific skin lesions of RA such as rheumatoid nodules, exacerbated nodules, rheumatoid vasculitis, Bywaters, pyoderma gangrenosum and neutrophilic rheumatoid dermatoses are discussed. Some of these lesions such as rheumatoid nodules are very common and some others are very rare.
Amir Hooshang Ehsani; Ali Naser Tork; Shideh Yazdanian
Volume 9, suppl.1 , 2006, , Pages 12-12
Abstract
Port-wine stain is a vascular malformation characterized pathologically by ectasia of superficial dermal capillaris and clinically by persistent macular erythema. The association of a port-wine stain on a limb with soft tissue swelling, with or without bony overgrowth, is termed klippel-Trenaunay syndrome. ...
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Port-wine stain is a vascular malformation characterized pathologically by ectasia of superficial dermal capillaris and clinically by persistent macular erythema. The association of a port-wine stain on a limb with soft tissue swelling, with or without bony overgrowth, is termed klippel-Trenaunay syndrome. Phakomatosis pigmento-vascularis is a combination of port-wine stain and cutaneous pigmentary abnormality.The patient who is described here is a 25-year-old man with Klippel-Trenaunay syndrome in association with bilateral Ota nevus. He can be classified as phakomatosis pigmento vascularis type IIa which is a relatively rare finding with this presentation.
Amir Hooshang Ehsani; Maryam Ghiasi; Reza M Robati
Volume 8, Issue 5 , 2005, , Pages 426-429