Saman Mohammadi; Saeedeh Farajzadeh; Hossein Safizadeh; Maryam Khalili; Mahin Aflatoonian; Rezvan Amiri; Elham Mohammadrezakhani
Abstract
Background: Atopic dermatitis is the most common inflammatory skin disease in children. Severe itching may lead to an impaired quality of life in the patients. In this study, we evaluated the validity and reliability of Persian version of a questionnaire regarding the infants’ ...
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Background: Atopic dermatitis is the most common inflammatory skin disease in children. Severe itching may lead to an impaired quality of life in the patients. In this study, we evaluated the validity and reliability of Persian version of a questionnaire regarding the infants’ dermatitis quality of life in children suffering from atopic dermatitis.Methods: When the original authors approved of the Persian version of the questionnaire, the parents completed the questionnaire for their 98 children with atopic dermatitis aged less than four years. We analyzed the data by SPSS 16. Cronbach’s alpha and inter-item and calculated the correlations to evaluate the reliability and validity via Kaiser criterion and scree plot.Results: The calculated mean score of questionnaire was 9.65±5.41. The first (itching and scratching) and eight questions (treatment problems) obtained the highest and lowest scores, respectively. There was a strong, positive correlation between the severity of the disease and the quality of life score in the patients. Cronbach’s alpha was calculated as 0.88 which is a sign of good internal consistency of the items. The inter-item correlative coefficients varied between -0.004 to 0.87. We used Kaiser’s criterion and scree plot to evaluate the validity and achieve a two-factor solution.Conclusion: Persian version of infants’ dermatitis quality of life index questionnaire was valid and reliable.
Saeedeh Farajzadeh; Soodabeh Zandi; Mohammad Mehdi Hayatbaksh Abbasi; Fahimeh Gadari; Armita Shahesmaeili; Behrooz Vares; Golamreza Hosseinpour; Iman Shojaei Baghini
Volume 14, Issue 3 , 2011, , Pages 81-85
Abstract
Background: The association between coronary artery disease and androgenic alopecia has been demonstrated, but few studies have focused on the mechanism of this association. The aim of this study was to evaluate the lipid profile in male pattern alopecia.Methods: In this case control study, 45 male patients ...
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Background: The association between coronary artery disease and androgenic alopecia has been demonstrated, but few studies have focused on the mechanism of this association. The aim of this study was to evaluate the lipid profile in male pattern alopecia.Methods: In this case control study, 45 male patients with androgenic alopecia who were aged from 20 to 50 years and 45 men with a normal hair status aged from 20 to 50 years were enrolled as the case and control groups, respectively. Lipid parameters including cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, lipoprotein (a), apolipoprotein A1, apolipoprotein B were measured in cases and controls.Results: A significant difference in serum lipoprotein (a) was observed between case and control groups (p< 0.001). We noted that 47.1 percent of the patients and 17.96% of the controls had a lipoprotein (a) level more than 30 mg/dl which is a critical level for coronary artery disease. There was no significant difference in other lipid parameters between two groups. The family history of androgenic alopecia and coronary heart disease was significantly higher in the cases than the controls.Conclusion: Considering the results of the study and the important role of lipoprotein (a) as a risk factor for atherosclerotic heart disease, we suggest that all men with a male pattern hair loss should be investigated for lipid indices, especially lipoprotein (a).