A Yazdanfar; K Karimirad; Kh Mani Kashani
Volume 7, Issue 1 , 2003, Pages 8-13
Abstract
Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This ...
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Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This study was a double blind, randomized, controlled clinical trial on 34 patients with common warts on palms and dorsum of their hands. These patients were randomly divided into two groups: 18 patients were treated with intralesional injections of bleomycin and 16 patients were treated with intralesional injections of normal saline. After 3 weeks of treatment, patients were evaluated and in case of unresponsiveness the second injection with the same medication was attempted. This group was visited again 3 weeks later and finally response to treatment ad possible complications were evaluated. Results: In bleomycin group 88.9% and in normal saline group 56.3% remitted (Fisher’s exact test, P<0.05). Conclusion: Intralesional bleomycin is an effective and low risk treatment of common resistant warts on palms and dorsum of hands.
M Akhyani; H Mortazavi; M Izadi; AH Ehsani
Volume 7, Issue 1 , 2003, Pages 14-18
Abstract
Background: Pityriasis rosea is an acute, inflammatory and self-limited disease, which is characterized by a primary scaly plaque (Herald patch) followed by a generalized, symmetrical papulosqumous eruption (Mostly on trunk and proximal extremities). Objective: To determine the efficacy of erythromycin ...
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Background: Pityriasis rosea is an acute, inflammatory and self-limited disease, which is characterized by a primary scaly plaque (Herald patch) followed by a generalized, symmetrical papulosqumous eruption (Mostly on trunk and proximal extremities). Objective: To determine the efficacy of erythromycin in the treatment of patients with pityriasis rosea. Patients and Methods: In this double-blind randomized clinical trial, 46 patients with pityriasis rosea in two equal groups were treated with oral erythromycin 1gr per day or placebo for seven days and were followed 1, 2 and 6 weeks after treatment. The response to the treatment was evaluated as complete, partial and no response. Results: In 48% of the case group and 13% of the control group complete response was seen at the end of first week of treatment. Moreover, these rates reached 91% and 57% at the end of second week, 100% and 87% at the end of sixth week, respectively. The differences between two groups were statistically significant after first and second weeks. Conclusion: Oral erythromycin was effective in the treatment of patients with pityriasis rosea. Also, it reduces the duration of disease.
F Farnaghi; H Seirafi; AR Firooz; F Jamshidi
Volume 7, Issue 1 , 2003, Pages 19-23
Abstract
Background: Psoriatic arthropathy is a seronegative arthropathy seen in some patients with psoriasis, a self-limited and genetically determined skin disease. Objective: To determine the prevalence and risk factors of arthropathy in patients with psoriasis. Patients and Methods: In a prospective, cross-sectional ...
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Background: Psoriatic arthropathy is a seronegative arthropathy seen in some patients with psoriasis, a self-limited and genetically determined skin disease. Objective: To determine the prevalence and risk factors of arthropathy in patients with psoriasis. Patients and Methods: In a prospective, cross-sectional study, psoriatic patients referred to Razi Skin Hospital in Tehran, Iran in 2002 were evaluated for the presence of arthropathy, and were referred to a rheumatologist for confirmation of arthropathy. The relationship between and nail involvement were evaluated using chi-square and t tests. Results: Among 320 patients with psoriasis, 29 (9.1%) had joint diseases. The most common was asymmetric polyarthritis. Patients with joint diseases had more nail involvement (96.5% vs. 73.1%, P<0.05) and higher mean PASI scores (24.33±10.35 vs. 10.70±8.44, P<0.05) than those without arthropathy, but the age and sex distribution of two groups were not significantly different. Conclusion: The prevalence of joint diseases in psoriatic patients in this study was similar to other reports. Nail involvement and more extensive disease are risk factors for joint diseases in these patients.
M Motavali Emami; MA Nilforoosh Zadeh; M Yazdi
Volume 7, Issue 1 , 2003, Pages 24-28
Abstract
Background: Increasing in the prevalence of pediculosis among school students and upward trend of pesticide marketing with evidence of resistance to them, indicate the possibility of lice resistance. Objective: To compare 3 drug formulations including: Lindan shampoo 1%, permethrin shampoo 1% and Copex ...
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Background: Increasing in the prevalence of pediculosis among school students and upward trend of pesticide marketing with evidence of resistance to them, indicate the possibility of lice resistance. Objective: To compare 3 drug formulations including: Lindan shampoo 1%, permethrin shampoo 1% and Copex powder 0.5% in the treatment of head lice infestation. Patients and Methods: Ninety students with a confirmed diagnosis of pediculosis were selected from rural schools and randomly treated in 3 equal groups with the mentioned medications. The results were evaluated after 24 hours, 1, 2 and 6 weeks. Results: The rate of healing was 83.3%, 100%, 100% after 24 hours, 70%, 93.3%, 90% after 1 week, 63.3%, 90%, 76.7% after 2 weeks and 40%, 83.3%, 66.7% after 6 weeks in patients treated with Lindan, permethrin, and Copex powder, respectively (P<0.05, chi-square test). Conclusion: Considering the numerous side effects of current treatment options like Lindan, alternative treatments must be trailed especially in fall and winter because of high rate of infestation during these seasons to interfere with resistancy.
J Golchai; O Zargari; M Gholipour; M Karbasi
Volume 7, Issue 1 , 2003, Pages 29-32
Abstract
Background: Scabies is a contagious skin disorder and one of the most common itching dermatoses in whole of the world. Epidemiologic survey of scabies periodically done in many countries is a reflection of general status of public health in the community. Objective: To determine the prevalence of the ...
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Background: Scabies is a contagious skin disorder and one of the most common itching dermatoses in whole of the world. Epidemiologic survey of scabies periodically done in many countries is a reflection of general status of public health in the community. Objective: To determine the prevalence of the scabies and its relationship with age, sex family size and place of residence. Patients & Methods: In this observational-cross sectional study on the students of primary schools in Somea-Sara in 2000-2001, 3656 students (On the basis of stratified random sampling) were selected and examined. The diagnosis of scabies was made on the basis of clinical criteria and the demographic data were recorded. Results: 50 out of 3656 students (1.36%) were suffered from scabies. The prevalence of scabies was 1.0% in urban schools and 1.61% in rural schools, 1% in male students and 1.7% in female students. The most common age group was 8-9 years and the mean of family size in patients was 6.1 and 6.2 in urban and rural areas, respectively. Conclusion: This study indicated that prevalence of scabies is higher in lower socio-economic state and larger family size.
AR Keshtkar Jafari; M Akhyani; A Akhavan Malayeri; V Kheiri
Volume 7, Issue 1 , 2003, Pages 33-37
Abstract
Background: Alopecia areata is a patchy hair loss that may occur in any hair bearing area on the body. There are many reports of ocular abnormalities such as lens and retinal changes in alopecia areata. Objective: To evaluate ocular alterations in alopecia areata with regard to the lens and retina. Patients ...
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Background: Alopecia areata is a patchy hair loss that may occur in any hair bearing area on the body. There are many reports of ocular abnormalities such as lens and retinal changes in alopecia areata. Objective: To evaluate ocular alterations in alopecia areata with regard to the lens and retina. Patients & Methods: Seventy three patients with alopecia areata including 34 males and 39 females, 69.6% partialis, 11% totalis and 19.2% universalis, were examined with slit lamp, fundoscopy and indirect ophthalmoscopy after full dilatation of pupils. Results: There was not any changes in patients’ lens and retina in this study. Conclusion: This study showed that lens and retinal changes are uncommon in alopecia areata.
MR Mortazavi; Z Safaei Naraghi; M Mohammad Zadeh
Volume 7, Issue 1 , 2003, Pages 38-42
Abstract
Actinic lichen planus is a clinical variant of lichen planus, involving mainly sun-exposed areas and manifested as annular lesions with a pigmented center surrounded by a hypopigmented zone. A rare presentation of actinic lichen planus mimics melasma but have distinctive histopathologic picture in favour ...
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Actinic lichen planus is a clinical variant of lichen planus, involving mainly sun-exposed areas and manifested as annular lesions with a pigmented center surrounded by a hypopigmented zone. A rare presentation of actinic lichen planus mimics melasma but have distinctive histopathologic picture in favour of actinic lichen planus. Herein, we report a 14-year-old boy who presented with a melasma-like patch on the left side of forehead. Histopathologic findings including pigmentation of basal layer accompanied with vacuolization and also pigmentary macrophages in dermis were in favour of actinic lichen planus.
A Asilian; S Karbasioun
Volume 7, Issue 1 , 2003, Pages 43-45
Abstract
Linear morphea is a distinct form of morphea that occurs as a linear band usually with a single unilateral distribution. The lower extremities are most often involved. This dermatosis appears as a linear induration not necessarily related to the derm induration. We report herein a case of 20-year-old ...
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Linear morphea is a distinct form of morphea that occurs as a linear band usually with a single unilateral distribution. The lower extremities are most often involved. This dermatosis appears as a linear induration not necessarily related to the derm induration. We report herein a case of 20-year-old Iranian girl who had a linear sclerotic patch on right lower extremity with clinical and pathologic diagnosis of linear morphea. Several perforating papules appeared on the lesion after 6 months, confirmed as perforating dermatosis by the biopsy.
MR Mortazavi
Volume 7, Issue 1 , 2003, Pages 46-50
Abstract
Localized scalp hair loss has different causes which alopecia areata, trichotillomania, tinea capitis and early lupus erythematosus are the most important ones. There are several reports of localized alopecia after tick and flea bites and bee stings, but there is only one report of ant-induced alopecia ...
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Localized scalp hair loss has different causes which alopecia areata, trichotillomania, tinea capitis and early lupus erythematosus are the most important ones. There are several reports of localized alopecia after tick and flea bites and bee stings, but there is only one report of ant-induced alopecia in the literature. We report herein two cases of alopecia induced by ants of genus Pheidole (Species pallidula).
