Sunil Gupta; Jaspriya Sandhu; Palvi Singla; Aditi Bansal; Bhavna Garg; Harpreet Kaur
Abstract
Rheumatoid vasculitis, an uncommon extraarticular manifestationof rheumatoid arthritis, usually develops in long-standing casesaffecting small-to-medium-sized vessels. It is a poor prognosticmarker when multiple systems are affected, skin and neurologicinvolvement being most frequent. Rheumatoid vasculitis ...
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Rheumatoid vasculitis, an uncommon extraarticular manifestationof rheumatoid arthritis, usually develops in long-standing casesaffecting small-to-medium-sized vessels. It is a poor prognosticmarker when multiple systems are affected, skin and neurologicinvolvement being most frequent. Rheumatoid vasculitis is seenmore commonly in seropositive and nodular rheumatoid arthritispatients who are male or smoke. Herein, we present the peculiarcase of a 48-year-old female with rapid onset, progressive, multipleulcers predominantly over the flexures. Differential diagnoses ofpyoderma gangrenosum, pyoderma vegetans, pemphigus vegetans,and vasculitis were considered, and the patient was evaluated. Oninvestigation, her rheumatoid factor titer was strongly positive;a skin biopsy revealed leukocytoclastic vasculitis. On clinical,serological, and histopathological correlation, a diagnosis ofrheumatoid vasculitis was made, responding well to high-doseprednisolone. On follow-up at six months, her skin lesions hadhealed well with moderate scarring; however, she developedsevere joint pain, warranting the initiation of disease-modifyingantirheumatic drugs. To the best of our knowledge, this is apreviously unreported clinical and morphological presentationof rheumatoid vasculitis.
Jaspriya Sandhu; Sunil Kumar Gupta; Navneet Kaur; Aditi Bansal; Bhavna Garg
Abstract
Acquired digital fibrokeratoma (ADFK) is a rare benign fibroustissue tumor that occurs over the extremities, predominantly inthe periungual area. We report a case of ADFK over the digitof the right hand presenting as a finger-like growth; the base ofthe lesion showed a collarette of scales. The lesion ...
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Acquired digital fibrokeratoma (ADFK) is a rare benign fibroustissue tumor that occurs over the extremities, predominantly inthe periungual area. We report a case of ADFK over the digitof the right hand presenting as a finger-like growth; the base ofthe lesion showed a collarette of scales. The lesion was excisedwith ablative CO2 laser. The histopathology was typical, showinghyperkeratosis and acanthosis. The core of the lesion had abundantcollagen fibers perpendicular to the long axis of the epithelium.There was good healing with minimal scarring; the patient wasfollowed up, and no recurrence was reported more than oneyear later. ADFK is a relatively rare tumor, with less than 150cases reported worldwide; we present a concise review of thepublished ADFK cases with their clinical and histopathologicalcharacteristics. To the best of our knowledge, this is the seventhsuch case to be reported from India.