Azadeh Goodarzi; Mahsa Farshidzadeh; Elham Behrangi; Mohammadreza Ghassemi; Masoumeh Roohaninasab
Abstract
Viral skin diseases range from simple superficial exanthems to complex systemic diseases, affecting people of all ages. Careful assessment of infectious contacts and immunization status is of considerable importance along with a thorough physical examination. Recent research has linked a deficiency of ...
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Viral skin diseases range from simple superficial exanthems to complex systemic diseases, affecting people of all ages. Careful assessment of infectious contacts and immunization status is of considerable importance along with a thorough physical examination. Recent research has linked a deficiency of vitamin D to an increased risk of autoimmune, infectious, and atopic disorders. Intralesional vitamin D3 may be an effective treatment option for warts. Vitamin D3 derivatives are effective for various skin conditions, including psoriasis, transient acantholytic dermatosis, actinic porokeratosis, and keratosis palmaris et plantaris. Vitamin D3 treatment has been shown to decrease chemokine synthesis and monocyte trafficking, as well as to downregulate toll-like receptors (TLRs) 2 and 4 of monocytes. This suggests an association between TLRs and vitamin-D-mediated innate immunity. The effect of vitamin D derivatives was speculated to be derived from its potential to regulate epidermal cell proliferation and differentiation and to modulate cytokine production. According to some studies gathered here, not only we can use different forms of vitamin D as therapy for viral skin disease, but also there is an important relationship between them. Therefore, we should consider the serum level of vitamin D for better management of these disorders. Also, keeping vitamin D levels within the normal range may be a preventative healthcare strategy.
F Zandi; S Shamsaddini; N Kambin
Volume 2, Issue 3 , 1999, , Pages 25-30
Abstract
Molluscum contagiosum is an infectious viral disease. The necessity to do this research in primary school of Kerman is mainly based on the high occurrence of the molluscum contagiosum (MC) among children, though an increase of the incidence of MC in adults with AIDS and immune deficiencies has also been ...
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Molluscum contagiosum is an infectious viral disease. The necessity to do this research in primary school of Kerman is mainly based on the high occurrence of the molluscum contagiosum (MC) among children, though an increase of the incidence of MC in adults with AIDS and immune deficiencies has also been reported. Among 1181 girls and 1440 boys, 75 were infected with MC; 29 (2.45%) and 46 (3.1%) cases were infected respectively, however these differences were not statistically significant. The effect of factors such as age, sex, parent’s level of education and occupation, and the size of family on the incidence of MC were studied. In this research the overall incidence of MC was 2.9%, but the highest rate of incidence was among children at the age of 6. Furthermore the incidence among children in public schools were more than private schools and children from families with low education and also larger families was higher, though these differences were not statistically significant.