Zohreh Tehranchinia; Hoda Rahimi; Mansour Moradloo
Volume 13, Issue 3 , 2010, , Pages 82-86
Abstract
Background: Benign pigmented lesions, including freckles, are common and various treatment modalities including lasers and peeling have been evaluated for their effectiveness in their treatment.Objective: To compare the clinical effects of focal peeling with Trichloroacetic Acid (TCA) and Nd:YAG (532 ...
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Background: Benign pigmented lesions, including freckles, are common and various treatment modalities including lasers and peeling have been evaluated for their effectiveness in their treatment.Objective: To compare the clinical effects of focal peeling with Trichloroacetic Acid (TCA) and Nd:YAG (532 nm) laser on freckles.Methods: Twenty patients with freckles were treated with focal peeling with TCA 25% on their left-sided lesions and Nd:YAG (532 nm, Fluence 9.5 J/cm2, spot size 1.5 mm) on their right-sided lesions. Photographs were taken prior to treatment and at follow-up visits and were evaluated by three dermatologists and the results were analyzed.Results: Eighteen out of the 20 patients (90%) with freckles manifested more than 50% improvement in laser treated areas whereas clinical improvement in focal peeling treated areas was observed in 15 out of 20 (75%). The mean improvement rate for laser and focal peeling was 66.50±12% and 58.3±15%, respectively. No significant difference was observed in the treatment results between these modalities.Conclusion: Focal peeling with TCA 25% could be as effective as frequency-doubled Nd:YAG (532 nm) laser in the treatment of freckles.
MJ Nazemi; S Arad; H Haji Hosseini; AH Ehsani
Volume 6, Issue 4 , 2003, , Pages 24-27
Abstract
Background: Comedone formation has an essential role in pathophysiology of acne, therefore destroying of comedones and preventing of comedone formation is very important in acne treatment. Objective: To determine the effect of superficial peeling with 70% glycolic acid in the improvement of acne. Patients ...
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Background: Comedone formation has an essential role in pathophysiology of acne, therefore destroying of comedones and preventing of comedone formation is very important in acne treatment. Objective: To determine the effect of superficial peeling with 70% glycolic acid in the improvement of acne. Patients and Methods: In this open clinical trial without control group, 30 patients with acne referred to Razi Hospital in Tehran (Mean age 18) years were treated with 70% glycolic acid and their clinical improvement was evaluated. Results: Mean numbers of comedones were 24.4±15.2 and 2.6±5.9 in first and last visits respectively (P<0.005). Moreover, 18 patients (60%) and 12 patients (40%) had complete and relative improvement, respectively. The side effects of this treatment were minimum and transient. Conclusion: Superficial peeling with 70% glycolic acid is effective in treatment of mild acne.