Farnoosh Seirafianpour; Farzaneh Mashayekhi; Milad Dodangeh; Forough Seifi Gharabaghloo; Masoud Pourghahramani Koltapeh; Ali Jamshidi Naeini; Rohollah Valizadeh; Davood Lakestani; Samaneh Mozafarpoor; Azadeh Goodarzi
Abstract
Background: About 20% of patients with coronavirus disease2019 (COVID-19) present with mucocutaneous eruptions. Earlyskin or dermatological manifestations can help pediatriciansprevent the spread of the disease by suspecting COVID-19 inasymptomatic or minimally symptomatic patients.Methods: PubMed, Scopus, ...
Read More
Background: About 20% of patients with coronavirus disease2019 (COVID-19) present with mucocutaneous eruptions. Earlyskin or dermatological manifestations can help pediatriciansprevent the spread of the disease by suspecting COVID-19 inasymptomatic or minimally symptomatic patients.Methods: PubMed, Scopus, Embase, Google Scholar, and theNottingham University website were searched on Sep. 1st, 2020,to retrieve studies regarding COVID-19-related mucocutaneousmanifestations in patients under the age of 18.Results: Data were extracted from 76 articles including 38,387 cases.Chilblain/pernio-like lesions were the most common dermatologicalmanifestation, followed by multisystem inflammatory syndrome inchildren (MIS-C)/Kawasaki-like syndrome. Most dermatologicalsigns were self-limited, presenting before, simultaneously with,or after other COVID-19 manifestations. In 40% of the affectedchildren, these signs were the sole presentation of COVID-19.Conclusion: During the COVID-19 pandemic, each newmucocutaneous event in children, especially acral lesions withvascular color, should be considered a possible indicator ofCOVID-19.
Ravindranath B Chavan; Vasudha A Belgaumkar; Nitika S Deshmukh; Ranjitha Krishnegowda
Abstract
Papulosquamous disorders constitute one of the common pediatric dermatoses. They are a heterogeneous group consisting of psoriasis, eczema, pityriasis rubra pilaris, and other conditions, where the differential diagnoses are close to each other clinically. Moreover, the presentation of the same disease ...
Read More
Papulosquamous disorders constitute one of the common pediatric dermatoses. They are a heterogeneous group consisting of psoriasis, eczema, pityriasis rubra pilaris, and other conditions, where the differential diagnoses are close to each other clinically. Moreover, the presentation of the same disease in children can differ from that occurring in adults. We report two infants with erythematous scaly papules and plaques diagnosed as two different disorders, albeit with a grossly similar appearance. Both these dermatoses are considered to be quite uncommon in infancy and can pose significant challenges in management. These disorders sometimes present with atypical variants, rendering it increasingly difficult to distinguish them. Some of these disorders tend to progress to erythroderma, and the infant may occasionally present directly in the erythrodermic stage, further compounding the conundrum. In such situations, identification of subtle clinical and histopathological clues allows accurate diagnosis, which is imperative for appropriate prognostication and treatment. This article illustrates the importance of histopathology and immunohistochemistry in aiding diagnosis and outlines the management of these disorders while emphasizing the importance of timely intervention in averting inadvertent complications in these young individuals.
Maryam Sadat Sadati; Nahid Hemmatian Boroujen; Mozhdeh Sepaskhah
Abstract
Subcutaneous fat atrophy at the site of multiple injections can follow intradermal or intramuscular administration of steroids to treat inflammatory diseases. This condition takes several months to develop, and usually patients seek medical attention due to cosmetic deformities. Several methods, including ...
Read More
Subcutaneous fat atrophy at the site of multiple injections can follow intradermal or intramuscular administration of steroids to treat inflammatory diseases. This condition takes several months to develop, and usually patients seek medical attention due to cosmetic deformities. Several methods, including fat transfer, filler injection and normal saline injection haven been proposed to treat steroid-induced atrophy. However, no standard procedure has been established for normal saline injection in terms of quantity and time interval between sessions. Normal injectable saline was administered every other week for 3 months, followed by 3 months’ rest. During follow-up, the response was satisfactory. As far as the authors are aware, this is the first demonstration of this method’s applicability to cases of steroid-induced atrophy in pediatric settings.
