Vahideh Lajevardi; Seyede Zahra Ghodsi; Maryam Daneshpazhooh; Homa Kazemi; Zeinab Aryanian; Azadeh Goodarzi
Volume 17, Issue 1 , 2014, , Pages 13-17
Abstract
Background: Acne vulgaris is a common skin disorder that affects 79% to 95% of the young population. Some studies have focused on the role of overweight and obesity in initiation and exacerbation of acne. This study investigated the relationship between BMI and the severity of acne. Method: This cross-sectional ...
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Background: Acne vulgaris is a common skin disorder that affects 79% to 95% of the young population. Some studies have focused on the role of overweight and obesity in initiation and exacerbation of acne. This study investigated the relationship between BMI and the severity of acne. Method: This cross-sectional study was conducted on 107 acne patients. One form was completed for each patient with regard to demographic characteristics including age, sex, weight, height, BMI, and also the severity of acne based on the Global Acne Severity Scale (GEA Scale), duration of the disease, type of medication, smoking history, duration of exposure to sunlight and intake of dairy products and chocolate. Result: In this study, 93 patients (86.9%) were female and 14 patients (13.1%) were male, with a mean age of 22.5 years. The mean BMI of the participants was 23.36 kg/m2 . With regard to acne severity groups, the moderate acne group had the highest frequency in total (37.4%). The highest mean BMI was seen in the very severe acne group (24.4 kg/m2 ), and the lowest mean BMI was observed in the severe acne group (21.86 kg/m2 ). There was no significant correlation between the acne severity and BMI (p=0.806).The mean disease duration was 4.13 years, which was not significantly associated with BMI. There was no significant association between the type of medical therapy and BMI. Conclusion: The prevalence of acne with severity more than moderate was much lower in patients who were underweight (BMI less than 18.5). However, this study showed no statistically significant difference in BMI among people with different severities of acne. Population-based studies, as well as age restriction of the participants, can lead to more accurate and reliable results in this regard.
Azizzadeh Maryam; Malek Mojtaba; Amiri Mehdi; Ghorbani Raheb
Volume 12, Issue 3 , 2009, , Pages 79-81
Abstract
Background: Psoriasis vulgaris is a common chronic and inflammatory disease of skin that its etiology is not completely known. However, it seems that genetic and environmental factors play a role in this disease. In vitro studies show that prolactin as a neurohormone has an etiologic effect on psoriasis. ...
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Background: Psoriasis vulgaris is a common chronic and inflammatory disease of skin that its etiology is not completely known. However, it seems that genetic and environmental factors play a role in this disease. In vitro studies show that prolactin as a neurohormone has an etiologic effect on psoriasis. This study aimed to compare serum prolactin levels in psoriatic patients with control group. Method: Prolactin level in serum was measured with ELISA method in 30 patients with psoriasis vulgaris and in 30 healthy persons as control group, which they had been matched with a view to age and sex. Result: Mean serum prolactin level in psoriatic patients was not significantly higher than control group. However, there was statistically significant relation between severity of disease and serum prolactin levels (r= 0.521, p=0.003). Conclusion: Positive relation between severity of psoriasis vulgaris and serum prolactin levels may suggest that prolactin is an index that shows severity of disease.