The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial
Background: Topical corticosteroids are currently used for treatment of diaper dermatitis. Previous studies have shown the efficacy of sucralfate in the treatment of diaper dermatitis and contact dermatitis in peri-stomy areas. Objectives: To evaluate the efficacy of topical sucralfate in comparison with hydrocortisone cream in the treatment of diaper dermatitis. Patients and Methods: In a double-blind, randomized clinical trial, 64 patients with diaper dermatitis were treated with sucralfate cream 4% or hydrocortisone cream. The duration of treatment was 8 weeks and patients were evaluated every two weeks until complete healing. The results were evaluated with chi-square test. Results: Complete healing (More than 50% improvement) occurred in 90.6% and partial healing (20-50% improvement) in 9.4% of patients in each group (P>0.05). Conclusion: Topical sucralfate is an effective, available and cheap therapeutic intervention for diaper dermatitis, which has equal efficacy with topical hydrocortisone cream.
Iraji,F. and Rezazadeh,M. (2003). The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial. Iranian Journal of Dermatology, 6(3), 8-12.
MLA
Iraji,F. , and Rezazadeh,M. . "The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial", Iranian Journal of Dermatology, 6, 3, 2003, 8-12.
HARVARD
Iraji F., Rezazadeh M. (2003). 'The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial', Iranian Journal of Dermatology, 6(3), pp. 8-12.
CHICAGO
F. Iraji and M. Rezazadeh, "The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial," Iranian Journal of Dermatology, 6 3 (2003): 8-12,
VANCOUVER
Iraji F., Rezazadeh M. The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial. Iran J Dermatol, 2003; 6(3): 8-12.
