FZ Pezeshk Poor; MJ Yazdan Panah; A Shir Del
Volume 9, Issue 3 , 2006, , Pages 227-232
Abstract
Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant ...
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Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Materials and Methods: In this descriptive study the demographic and clinical data of 23 patients suffering from ATLL who were admitted in hematology and dermatology departments of Ghaem Hospital, during 1995-2004 and had specific cutaneous lesions confirmed histopathologically with atypical lymphocytes in skin lesions, were recorded and analyzed.Results: Eleven patients were male and 12 were female. The mean age of patients was 48.17±14.1 years. Birth places of over 85% of cases were north of Khorasan. The most common types of specific skin lesions were maculopapular rash in 11 cases (47.8%) and papular lesions in 4 cases (17.4%). Other lesions included plaque, icthyosis like, erythroderma, tumor, and nodular lesions. In most of patients (56.5%) the skin lesions were generalized.Conclusion: The most common type of specific skin lesions in ATLL was maculopapular rash especially with generalized distribution. Other types of specific skin lesions in order of frequency were papule, plaque, icthyosis like, nodule, tumor and erythroderma.
MH Amouzgar; MJ Yazdan Panah; M Ebrahimi Rad
Volume 9, Issue 1 , 2006, , Pages 28-34
MJ Yazdan Panah; R Nour Bakhsh; P Layegh; M Saghafi
Volume 9, Issue 1 , 2006, , Pages 89-95
MJ Yazdan Panah; M Ebrahimi Rad; MJ Mojahedi
Volume 8, Issue 4 , 2005, , Pages 281-286
Abstract
Background and objective: Renal transplantation is an appropriate treatment for end stage renal disease and helps prolongation of patients survival with better quality, but immunosuppressive drugs that are used for inhibition of rejection after transplantation may cause some adverse effects in other ...
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Background and objective: Renal transplantation is an appropriate treatment for end stage renal disease and helps prolongation of patients survival with better quality, but immunosuppressive drugs that are used for inhibition of rejection after transplantation may cause some adverse effects in other organs such as the skin. Apparently, early recognition of those side effects and their appropriate management can reduce morbidity and mortality. This study was designed to study cutaneous complications in renal transplantation recipients. Materials and Methods: In this descriptive study cutaneous side effects in one hundred kidney transplant patients who admitted to transplantation clinics of Ghaem and Imam Reza hospital of Mashhad during a six-month period (April to September 2003) were studied. Results: Sixty-five patients were males and 35 cases were female. The mean age was 36 years (SD=14). Totally, cutaneous manifestations were observed in 88% of patients. In an descending order they included hypertrichosis, cushingoid appearance, gingival hypeplasia, steroid acne, common warts, herpes simplex infection, superficial fungal infection, candidiasis. Actinic keratosis, porokeratosis, lymphoma, stria, telangiectasia and sebaceous hyperplasia. Conclusion: Early recognition of these complications and appropriate treatment of them can reduce probable mortality and morbidity.
F Pezeshk Pour; MJ Yazdan Panah; AR Taheri; H Assadi
Volume 6, Issue 4 , 2003, , Pages 28-30
Abstract
Background: Vitiligo is a common autoimmune skin disease that may occur in association with other autoimmune disorders especially those of the endocrine system. Diabetes mellitus is a common endocrine disease associated with vitiligo. Objective: To study the association of vitiligo and diabetes mellitus. ...
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Background: Vitiligo is a common autoimmune skin disease that may occur in association with other autoimmune disorders especially those of the endocrine system. Diabetes mellitus is a common endocrine disease associated with vitiligo. Objective: To study the association of vitiligo and diabetes mellitus. Patients and Methods: In this descriptive cross-sectional study, 750 diabetic patients referred to Mashhad Diabetes Center were studied in Shahrivar 1380. Results: Thirty-two (4.3%) of these patients suffered from vitiligo that mostly was of generalized type. The face was the most common site of involvement. Twenty-two patients (68.7%) were female and 10 patients (31.3%) were male. Five percent of female and 3.3% of male diabetics suffered from vitiligo. 4.2% of NIDDM diabetics and 4.7% of IDDM diabetics suffered from vitiligo. Conclusion: Vitiligo was more common in NIDDM than IDDM because of the higher prevalence of NIDDM, but the association of vitiligo with IDDM was stronger. Vitiligo was more common in female than male diabetics.
MJ Yazdan Panah; SK Mostoufi; M Soleimani
Volume 6, Issue 2 , 2003, , Pages 20-24
Abstract
Background: Different local and systemic modalities are suggested in the treatment of cutaneous leishmaniasis (CL), but the pentavalent antimony compounds are still considered as the first line of treatment. Regarding to increase in clinical drug resistance, adverse effects and low compliance of patient, ...
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Background: Different local and systemic modalities are suggested in the treatment of cutaneous leishmaniasis (CL), but the pentavalent antimony compounds are still considered as the first line of treatment. Regarding to increase in clinical drug resistance, adverse effects and low compliance of patient, efforts for finding a more effective and safer drug continue. Objectives: To evaluate the efficacy of oral zinc sulfate in the treatment of acute dry CL. Patients and Methods: 31 patients with clinical diagnosis of acute, dry CL and positive direct smear for Leishman bodies were included in the trial. Patients were treated with 10 mg/kg/day oral zinc sulfate for 45 days and evaluated every 3 weeks during the period of treatment and also 1.5 months after cessation of it. Results: 22 patients completed the course of treatment. At the end of 45 days of treatment, only two cases (9%) were cured and the remaining did not show satisfactory response. Conclusion: Oral zinc sulfate has limited therapeutic value in the treatment of dry CL.
