Reza Yaghoobi; Niloofar Sina; Nastaran Ranjbari; Rana Rafiei
Volume 9, suppl.1 , 2006, , Pages 5-5
Abstract
Inflammatory linear verrucous epidermal nevus (ILVEN) is a unilateral skin disorder which usually manifests in infancy or childhood. Female predominance, frequent leg involvement, pruritus, resistance to treatment, and a psoriasiform histologic pattern are other common characteristics of this disease. ...
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Inflammatory linear verrucous epidermal nevus (ILVEN) is a unilateral skin disorder which usually manifests in infancy or childhood. Female predominance, frequent leg involvement, pruritus, resistance to treatment, and a psoriasiform histologic pattern are other common characteristics of this disease. Atypical presentations of ILVEN have been described and include late onset in life, widespread involvement and response to treatment. We report a 2-year-old otherwise healthy girl who had bilateral ILVEN and provide a review of this disease.
Reza Yaghoobi; Seyyed Arash Abtahian
Volume 10, Suppl.2 , 2007, , Pages 5-5
Abstract
Psoriasis is quite common in childhood, although congenital psoriasis is very rare. Here, we report a 2-year-old girl with typical linear psoriasis associated with bilateral hypopigmentation of breasts which has been present since birth.
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Psoriasis is quite common in childhood, although congenital psoriasis is very rare. Here, we report a 2-year-old girl with typical linear psoriasis associated with bilateral hypopigmentation of breasts which has been present since birth.
Azita Nikoo; Mona Masoumeh Naraghi
Volume 15, Issue 1 , 2012, , Pages 15-17
Abstract
Background: Accurate clinical information provided on dermatopathology requisition forms is often very important to achieve correct diagnosis. We searched to evaluate the clinical information actually provided on the Dermatopathology requisition forms of melanocytic lesions submitted to our laboratory. ...
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Background: Accurate clinical information provided on dermatopathology requisition forms is often very important to achieve correct diagnosis. We searched to evaluate the clinical information actually provided on the Dermatopathology requisition forms of melanocytic lesions submitted to our laboratory. Method: The provided clinical information and given microscopic diagnoses were recorded for melanocytic lesions submitted as wet tissue to our dermatopathology department. Result: Biopsy specimens were received from our dermatology clinics at our hospital that were filled in by residents of dermatology. According to ABCDE criteria, 76% of cases had none, 11.5% had one criterion, 19% had two criteria, 5.6% had 3 criteria, 1.1% had 4 criteria, and none had all 5 criteria. Asymmetry was provided in none of the requests, but border irregularity was provided in 7.6% of the time, color 10.1%, diameter 5.9%, and evolution 21.8%. No requisition forms mentioned the ‘‘ugly duckling’’ sign. Conclusion: Actually, most of the requisition forms did not provide the clinical information that is very important for the clinicopathologic correlation in the diagnosis of the pigmented lesions.
Jelvehgari Mitra; Azimi Hamide; Montazam Hassan
Volume 12, Issue 1 , 2009, , Pages 16-19
Abstract
Background: Cutaneous drug reaction seems to be relatively common The aim of the study was to recognize offending drugs, evaluate patients' characteristics and educate the patients to avoid selfadministration and re-administration of drugs. Methods: We retrospectively and prospectively analyzed data ...
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Background: Cutaneous drug reaction seems to be relatively common The aim of the study was to recognize offending drugs, evaluate patients' characteristics and educate the patients to avoid selfadministration and re-administration of drugs. Methods: We retrospectively and prospectively analyzed data from Sina hospital in Tabriz (2000-2005) to determine the number of hospitalizations and visits with primary diagnoses of skin conditions that are often attributed to drugs. A physical examination was done by a dermatologist who completed a standardized questionnaire. Requested information included patient characteristics (associated disorders, severity scores), drug intake and characteristics of the skin reaction (type, course).Using statistical methods for surveys, we determined the demographic characteristics of patients with these diagnoses. Results: Three hundred patients (148 males and 152 females) with cutaneous drug eruption were studied. The most common eruptions were erythroderma (41.3%) and maculopapular rash (26%) and the most common offending drugs were carbamazepine (28%), carbamazepinevalproate (20%) and Co-Ttrimoxazole-carbamazepine-diclofenac sodium combination (26.7%). The highest number of the patients belonged to the age group of 30-39 years (15%). The interval between developing lesions and intake of the offending drug varied from 1 day to 45 days. Drug reactions showed that 20-30% of the ADRs from anticonvulsants, 15-25% of the ADRS from sulfonamides, 10% of the ADRs from antibiotics, and 7% of the ADRs from non-steroidal antiinflammatory and anti-hypertensive drugs were dermatological. Conclusion: The pattern of ADRs and the drugs causing them is remarkably different in our population. Knowledge of these drug eruptions, the causative drugs and the prognostic indicators is essential for clinicians. It is recommended to advise patients to carry a card or some other form of an emergency identification in their wallets that lists drug allergies and/or intolerances, especially if they have had a severe reaction.
Barikbin Behrooz; Qeisari Mehdi; Saeedi Marjan; Esmailiazad Mitra; Moravvej Hamideh; Yousefi Maryam; Ahmadi Amrollah
Volume 13, Issue 1 , 2010, , Pages 16-19
Abstract
Background: Psoriasis is a common inflammatory skin disorder. There has been considerable interest in herbal medicine as a treatment for psoriasis. In a previous study HESA-A, a marine-herbal drug, was found to be beneficial in the treatment of psoriasis vulgaris. The aim of this study was to assess ...
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Background: Psoriasis is a common inflammatory skin disorder. There has been considerable interest in herbal medicine as a treatment for psoriasis. In a previous study HESA-A, a marine-herbal drug, was found to be beneficial in the treatment of psoriasis vulgaris. The aim of this study was to assess the efficacy and tolerability of HESA-A in patients with psoriasis. Methods: Nineteen patients with a mean PASI score of 13.04±6.14 (min=3.90, max=27.70) were recruited to receive daily dosage of 30 mg/kg of HESA-A tablets for at least 4 weeks. The patients were followed every two weeks for determining PASI score changes and drug side effects until the end of the study. Result: At the end of the study, the mean PASI score of the patients reduced to 9.60±5.30 (min=0.90, max=19.1). PASI score reduced in 14 patients (73.7%) and increased in 5 patients (26.3%) during the study. Two patients achieved 75 to 100% improvement in PASI score and two achieved 50 to 75%. In 10 patients (52.6%), 1 to 50% improvement in the PASI score was detected. There was a statically significant correlation between the duration of treatment and PASI improvement. (P-value = 0.024) Conclusion: Although this drug was very safe and tolerable, our study did not find rapid and acceptable efficacy in the treatment of chronic plaque psoriasis as shown in a previous study. According to our findings, HESA-A was more effective when used for a prolonged time and in respect of the safety profile of HESA-A, we can use this drug as a maintenance or adjuvant therapy for chronic plaque psoriasis in longer terms.
Hefazi Mahyar T; Moslehi Homayon; Ehsani Amir H; Ostadrahimi Nima
Volume 12, Suppl.3 , 2009, , Pages 16-18
Abstract
Vitiligo and Lichen Planus, two common dermatologic disorders, are expected to coexist. This leads to diverse theories regarding their immunopathogenesis linkage. In this case, we report a twenty-year-old man suffering from simultaneous lichen planus and vitiligo which were both generalized at the time ...
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Vitiligo and Lichen Planus, two common dermatologic disorders, are expected to coexist. This leads to diverse theories regarding their immunopathogenesis linkage. In this case, we report a twenty-year-old man suffering from simultaneous lichen planus and vitiligo which were both generalized at the time of observation and also concomitant throughout their entire course of progression. Lichen Planus papules were located on sun-exposed areas and non sun-exposed areas; both on vitiligenous areas and non-vitiligenous areas diminishing current theories about the association of the two diseases. Since we did not have the patient’s consent to perform a series of biopsies, we were unable to evaluate dermatopathology of the two diseases at different sites in regard to sun exposure. Further extensive researches on larger scales seem warranted to propose any kind of theory regarding their interconnection.
Mohammad Radmanesh; Ramin Radmanesh
Volume 16, Issue 1 , 2013, , Pages 17-20
Abstract
Background: Although cryotherapy has been reported as atechnique for depigmenting residual pigmented patches inpatients with universal vitiligo, Q-switched Nd-YAG lasershave not yet been used for this purpose. The aim of this studywas to compare the efficacy of cryotherapy with that of 532nmQ-switched ...
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Background: Although cryotherapy has been reported as atechnique for depigmenting residual pigmented patches inpatients with universal vitiligo, Q-switched Nd-YAG lasershave not yet been used for this purpose. The aim of this studywas to compare the efficacy of cryotherapy with that of 532nmQ-switched Nd-YAG laser therapy for depigmentation in patientswith universal vitiligo.Method: Six adult patients (4 male and 2 female) with universalvitiligo and facial residual pigmented patches were treatedsimultaneously with cryotherapy on the right and the frequencydoubled532nm Q-switched Nd-YAG laser therapy on the leftside. The laser parameters used were spot size 3-5mm, frequencyrate 10 hertz, and the fluence was 5J/cm2. The cryo system wasa closed contact CO2 Cryo gun. The patients were scheduled tobe treated monthly.Result: The depigmentation was complete after three successivesessions of cryotherapy and 30-45 days after the last session, incomparison with simultaneous 30-70% depigmentation of the laserside. No scar or permanent sequellae developed on either side.Conclusion: Cryotherapy is more effective and fast-actingthan Q-switched Nd-YAG laser for depigmentation of residualpigmented patches in patients with universal vitiligo.
M Vali Khani; H Ghani Nejad; M Barzegari; Z Hallaji; S Toosi
Volume 8, suppl , 2005, , Pages 18-23
Abstract
This is a report of a 40- year- old woman presented to our outpatient dermatology clinic. She had a 40- day history of sudden development of skin lesions on the exposed. Dermatologic examination revealed relatively limited brown – reddish plaques on the hands, feet, face, one elbow and groin regions. ...
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This is a report of a 40- year- old woman presented to our outpatient dermatology clinic. She had a 40- day history of sudden development of skin lesions on the exposed. Dermatologic examination revealed relatively limited brown – reddish plaques on the hands, feet, face, one elbow and groin regions. She has been taking carbamazepine (200 mg/ day) for 13 years. Otherwise, no serious problems were found. A clinical diagnosis of drug- induced pellagra was made based on the morphology. After discontinuing carbamazepine, treatment with nicotinamide (500 mg/day) was initiated and the eruption faded away and resolved within 3 weeks. Pellagra is a disease caused by a deficiency of the niacin and may occur with certain drugs.
Alireza Khatami; Pegeen Walsh
Abstract
The World Health Organization characterized the outbreak of the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), as a pandemic on March 11, 2020. According to official reports, over 12,300,000 individuals have caught the disease globally ...
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The World Health Organization characterized the outbreak of the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), as a pandemic on March 11, 2020. According to official reports, over 12,300,000 individuals have caught the disease globally over the past six months. Like many other professions, the disease has affected private and academic dermatology practices around the world. The disease has diverse and extensive skin manifestations with implications for dermatology education and research. Some other issues that may concern dermatologists during the pandemic include ethics pertaining to the optimal use of scarce resources like certain drugs and personal protective equipment as well as surcharging patients and the potential of increasing the size of the preexisting health inequity gap. Considering all these issues, discussing the ethical aspects of dermatology, i.e., dermatoethics, during this pandemic is critical. Herein, we review the four basic biomedical ethics principles of autonomy, beneficence, non-maleficence, and justice in the context of the COVID-19 pandemic.
Mohammad Ali Mapar; Sarah Hashemzade; Reza Yaghoobi
Volume 14, Issue 1 , 2011, , Pages 20-24
Abstract
Background: Topical corticosteroids and oral psoralen plus ultraviolet A radiation (PUVA therapy) are two common treatment methods for vitiligo. The aim of this study was to compare the efficacy, complications and patterns of repigmentation of these two methods. Methods: This prospective randomized clinical ...
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Background: Topical corticosteroids and oral psoralen plus ultraviolet A radiation (PUVA therapy) are two common treatment methods for vitiligo. The aim of this study was to compare the efficacy, complications and patterns of repigmentation of these two methods. Methods: This prospective randomized clinical trial was conducted from July 2007 to October 2008. Patients with disseminated vitiligo were divided into two groups. PUVA therapy was administered in one group and topical clobetasol was used in the other group. Results were recorded in 4 categories and therapeutic findings and complications were compared after 24 weeks. Results: Among 37 participants in the PUVA therapy group, 18 (48.6%) patients achieved marked and 14 (37.8%) patients showed good repigmentation. Similarly, among 35 participants in the clobetasol group, 6 (17.1%) patients showed marked and 8 (22.8%) patients showed good repigmentation. treatment complications were observed in 16.2% of the participants in PUVA group and 28.6% of the participants in clobetasol group. The patterns of repigmentation were different in the two groups. Conclusion: PUVA showed better therapeutic effects, and did not cause significant complications. Therefore, it could be used as one of the first line medications in the treatment of vitiligo.
Nematy Mohsen; Mehdizadeh Atieh; Razmpour Farkhondeh
Volume 18, Issue 1 , 2015, , Pages 20-24
Abstract
Background: Skin reflects the general health status and is not an exception in the process of aging. Intervention studies indicate that it is possible to delay skin aging and improve skin conditions through diet-based anti-aging strategies. The purpose of the current work was to review recent existing ...
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Background: Skin reflects the general health status and is not an exception in the process of aging. Intervention studies indicate that it is possible to delay skin aging and improve skin conditions through diet-based anti-aging strategies. The purpose of the current work was to review recent existing literature regarding the role of nutrition, for and against skin aging processes.Method: This review provides updates on the effects of nutrition strategies on skin aging developed during 2008-2014. Databases such as the ISI web of science, PubMed, Scopus and Google Scholar were investigated.Result: The most important role of nutrition on skin aging is by restricting the generation or activation of reactive oxygen species (ROS) which is considered as the main cause of extrinsic skin aging. Excess sugar in daily diet accelerates aging processes through the production of advanced glycation end products that inhibit proper repair of collagen fibers. Monounsaturated and omega-3 polyunsaturated fatty acids have inverse association with severe photoaging. Antioxidants such as vitamins C, A, E, carotenoids, flavonoids and botanical antioxidants such as resveratrol, curcumin and green tea polyphenols effectively decelerate this process. Zinc, selenium and copper are coenzymes of metallothioneins and glutathione that reduce intracellular oxidative stress and result in skin protection.Conclusion: The link between nutritional issues and skin aging is an interesting but conflicting subject that requires many interventional studies. Intracellular antioxidant mechanisms are the most effective protection against skin aging.
Farajzadeh Saeedeh; Zandi Soodabeh; Vares Behrooz; Sharifzadeh Mahdiyeh; Fekri Ali-Reza
Volume 11, Issue 1 , 2008, , Pages 21-24
Abstract
Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of ...
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Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in atopic dermatitis patients with the control group in an outpatient clinic in Kerman.Methods: This was a case – control study done on 459 patients with atopic dermatitis, who were diagnosed based on Hanifin & Rajka criteria and 400 healthy subjects without immunosuppression as our control group. The frequency of leishmaniasis was investigated in both groups according to age, gender and residential area.Results: Among 459 atopic dermatitis patients, 232 were female and 227 were male. Control group consisted of 232 males and 168 females. The mean age of the atopic dermatitis patients and the controls was 9.2 and 13.3 years, respectively (p0.05%). There was no statistically significant difference in clinical presentations of leishmaniasis between two groups.Conclusion: In this study there was no significant relationship between leishmaniasis and atopic dermatitis. This finding can be due to the small sample size or the difference between case and control groups regarding age.
M Shahidi Dadras; L Ataei
Volume 4, Issue 2 , 2001, , Pages 21-25
Abstract
Background: Mycosis fungoides (MF) is a cutaneous T cell lymphoma. There are only palliative treatments in advanced stages with no cure. Most chemotherapy regimens have temporary effects with various side effects. Objective: The objective of this study was to assess the efficacy of a new chemotherapy ...
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Background: Mycosis fungoides (MF) is a cutaneous T cell lymphoma. There are only palliative treatments in advanced stages with no cure. Most chemotherapy regimens have temporary effects with various side effects. Objective: The objective of this study was to assess the efficacy of a new chemotherapy regimens in advanced stages of MF. This regimens takes advantage of synergistic effect of methotrexate and fluorouracil and also uses leucovorin to reduce side effects of methotrexate. Patients and Methods: Five patients with advanced stages of MF (Stage IIB and higher) were treated with several courses of this chemotherapy regimens in a quasi experimental study. Results: Four patients responded partially one responded completely to this regimen but all of them relapsed after tapering the treatment. All of them tolerated the drugs well and no serious side effects were observed. Tumoral lesions showed better response. Conclusion: Although this chemotherapy regimen, similar to other regimens, only had temporary and palliative effects, it was tolerated well without serious side effects.
M Adabi; AR Firoozjahi; M Ghasemi
Volume 8, suppl , 2004, , Pages 21-25
Abstract
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized ...
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Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of serum antibody using ELISA method.
Reza Yaghoobi; Nader Pazyar; Hooman Kalantar; Azita Nikoo; Zahra Naraghi; Kambiz Kamyab; Alireza Ganadan; Zohre Khodashenas; Azadeh Goodarzi; Fatemeh Mohaghegh
Volume 20, Issue 1 , 2017, , Pages 21-25
Abstract
Background: Basal cell carcinomas (BCC) are the most prevalent among non-melanoma skin cancers (NMSC), which correspond to the most common skin cancers. BCC histopathological subtyping is a problem in therapeutic management. Therefore, we have decided to perform a histopathologic study for better classification ...
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Background: Basal cell carcinomas (BCC) are the most prevalent among non-melanoma skin cancers (NMSC), which correspond to the most common skin cancers. BCC histopathological subtyping is a problem in therapeutic management. Therefore, we have decided to perform a histopathologic study for better classification of BCCs based on interobserver diagnostic judgment. Methods: We conducted this cross-sectional study on 100 randomly selected pathologically confirmed BCC cases of various subtypes at Razi Hospital, Tehran, Iran during 2013 and 2014. A total of four dermatopathologists independently reviewed each pathology slide to evaluate the interobserver concordance rate. Results: The overall Fleiss’ kappa statistic (kappa) for the BCC subtypes was 0.18 (P<0.001), which indicated slight agreement. We observed moderate agreement on superficial and nodular BCC (kappa: 0.0-0.4); fair agreement on infiltrative and keratotic BCC (kappa: 0.2-0.4); and slight agreement on pigmented, micronodular, and metatypical BCC (kappa: 0.0-0.2). There was moderate agreement diagnosis for the low and high risk growth pattern categories. Conclusion: Overall, we found that the dermatopathologists had inconsistent nomenclature for the BCC subtypes, however they had better agreement for the diagnosis of superficial, nodular, and infiltrative subtypes and the high risk growth pattern.
Kamran Balighi; Zahra Ghodsi; Masoud Iravani; Maede Rayati Damavandi; Azadeh Goodarzi; Vahide Lajevardi; Sara Saburi; Alireza Faghihi Kashani
Volume 19, Issue 1 , 2016, , Pages 21-24
Abstract
Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: ...
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Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed with chronic mucocutaneous GVHD. We divided the patients into three major categories based on the type of skin lesions: sclerodermoid, lichenoid, and mixed. Patients received several packs of narrow band UVB (NBUVB) phototherapy. Each pack contained ten sessions of NBUVB (311 nm) with a duration of at least ten seconds and a fixed radiation dosage (6 mj/cm2) during the treatment.Results: There were 3 patients diagnosed with lichenoid skin lesions, 2 with sclerodermoid lesions, and 2 had mixed cGVHD lesions. During the follow up period one patient was excluded due to a lower respiratory tract infection. The mean response ratio was 42% with a mean satisfaction level of 5.5 out of 10. The lichenoid group had the best, most rapid response. There were no serious adverse effects reported.Conclusion: Narrow band UVB phototherapy is useful as an adjuvant therapeutic modality in cutaneous lichenoid and intraoral cGVHD with no serious adverse effects.
K Holubar
Volume 1, Issue 2 , 1998, , Pages 22-23
Shahzad Shahid; Taheri Ahmad Reza; Javidi Zari; Dorgalaleh Akbar; Tabibian Shadi; Bamedi Taregh; Dorgalaleh Saeed; Moemeni Mohammad
Volume 17, Issue 1 , 2014, , Pages 22-26
Abstract
Background: Vitiligo is a common acquired disorder of the skin. The disease is characterized by depigmented macules and patches on the skin. Autoimmunity has a crucial role in the pathogenesis of the vitiligo. Vitiligo is frequently associated with different autoimmune diseases such as thyroid abnormalities ...
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Background: Vitiligo is a common acquired disorder of the skin. The disease is characterized by depigmented macules and patches on the skin. Autoimmunity has a crucial role in the pathogenesis of the vitiligo. Vitiligo is frequently associated with different autoimmune diseases such as thyroid abnormalities and diabetes. This study aimed to evaluate the association between vitiligo and diabetes mellitus.Method: This case-control study was conducted on 70 patients with established vitiligo disorder and 70 non vitiligo individuals as the control group. In the case group, we performed two tests, fasting blood sugar (FBS) and oral glucose oral tolerance test (OGTT), while only FBS was checked in the control group.Result: The results of our study showed that out of 70 people in the case group, 18 (25.71%) had impaired FBS while only 4 (5.7%) had impaired GTT3. Statistical analysis showed p-value=0.015 which indicated a significant difference in impaired FBS between case and control groups. We had half and 1 hour GTT data (GTT1 and GTT2) and all patients with impaired GTT1 (4 individuals) and GTT2 (5 individuals) were females with a significant difference (P-value = 0.021 and 0.017, respectively).Conclusion: Periodical laboratory investigation for diabetes mellitus in vitiligo patients, particularly in females, seems to be necessary.
MA Mapar; P Bakhtiari Nia; F Zia
Volume 3, Issue 3 , 2000, , Pages 23-28
Abstract
Background: Basal cell carcinoma (BCC) is the most common skin cancer in humans showing various clinical and histological forms. Objective: The aim of this study was to evaluate the age, sex, location, histological subtypes of BCC cases in Ahwaz and to compare it with other skin cancers specially squamous ...
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Background: Basal cell carcinoma (BCC) is the most common skin cancer in humans showing various clinical and histological forms. Objective: The aim of this study was to evaluate the age, sex, location, histological subtypes of BCC cases in Ahwaz and to compare it with other skin cancers specially squamous cell carcinoma. Patients and Methods: A descriptive, retrospective study was done using files of Pathology Department of Imam Khomeini Hospital in Ahwaz. All files from 1366 to 1376 were searched and the files of patients with skin cancers were evaluated. Results: 1271 of about 70000 specimens were diagnosed as skin cancer. 896 of them (70.50%) were BCC. The incidence of BCC was equal in women and men. The mean age was 60 years. An interesting finding was the difference in the mean age of patients in the first 2 years (57.58 years) and last 2 years of study (63.27 years). Eighty percent of patients were in the age range of 40-80 years. The most frequent locations of the lesions were nose, cheeks, forehead and eyelids. The incidence of SCC (294 cases) was almost 1/3 of BCC. Conclusion: The most common skin cancer in Ahwaz is BCC. The frequency is equal in both sexes. The mean age is 60 years and is increasing with time.
Maryam Khalili; Mahin Aflatoonian; Alireza Zeinaddini; Rahim Ahmadi; Simin Shamsi Meymandi
Abstract
PHACES syndrome (Posterior Fossa Malformations, Hemangioma, Arterial Anomalies, Cardiac Defects and Coarctation of the Aorta, Eye Abnormalities, and Sternal Abnormalities or Ventral Developmental Defects) is a rare neurocutaneous syndrome, which characteristic feature is large segmental hemangioma. Extracutaneous ...
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PHACES syndrome (Posterior Fossa Malformations, Hemangioma, Arterial Anomalies, Cardiac Defects and Coarctation of the Aorta, Eye Abnormalities, and Sternal Abnormalities or Ventral Developmental Defects) is a rare neurocutaneous syndrome, which characteristic feature is large segmental hemangioma. Extracutaneous involvement is an important cause of morbidity in this syndrome.Described below is an infant with large hemangiomatous lesions on the right side of the face, suprasternal notch, midline sternal defect and supraumbilical raphe. Based on the new consensus on the diagnostic criteria of PHACES syndrome, a definitive diagnosis of PHACES syndrome has been corroborated. Accordingly, our patient was analyzed with regards to other clinical features through magnetic resonance imaging of the head, neck and abdomen, all of which were normal. In echocardiography, the patient showed atrial septal defect, in addition to ipsilateral conductive hearing loss, contralateral cataract and Horner’s syndrome, which was reported only in very few cases. The clinical presentation of the present case was different from most previous reported ones, as segmental hemangioma in PHACES syndrome was, for the most part, located on the left side of the face and ocular involvement was predominantly reported ipsilateral to hemangiomatous lesion.
N Esmaeili; M Safaei Pourzamani; F Rahimi
Volume 6, Issue 3 , 2003, , Pages 24-26
Abstract
Background: To get accustomed with cutaneous manifestations related to AIDS is effective in early diagnosis of this disease. Objective: To evaluate the cutaneous manifestations in HIV seropositive patients. Patients and Methods: A prospective, descriptive and cross-sectional study was performed on HIV-positive ...
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Background: To get accustomed with cutaneous manifestations related to AIDS is effective in early diagnosis of this disease. Objective: To evaluate the cutaneous manifestations in HIV seropositive patients. Patients and Methods: A prospective, descriptive and cross-sectional study was performed on HIV-positive male prisoners in Kermanshah central prison and in addiction camp, referred to skin disease center of Kermanshah University, during eleven months; and their cutaneous manifestations were analyzed. Results: 43 out of 79 patients (54.4%) had mucocutaneous manifestations. 26 patients (32.9%) had herpes zoster infection. Two patients (4.6%) developed recurrent herpes zoster and five patients (11.6%) showed wide scar in low back area and shoulder because of previous herpes zoster. Other manifestations included acne (23.3%), generalized pruritus (11.6%) and oral herpes simplex infection, scabies and tinea versicolor in few cases. The majority of patients (32.6%) were in the age group of 30-34 years. Conclusion: The most common cutaneous disease in this study was herpes zoster. Herpes zoster infection in patients without any obvious risk factor could be a predictor of probable HIV infection.
R Yaghoobi; AA Aliari; N Emad Mostovfi; SM Latifi
Volume 8, Issue 1 , 2004, , Pages 24-31
Abstract
Background: The incidence of oral cancers is different worldwide. Objective: To evaluate the rate of oral cancers in Khouzestan Province. Patients and Methods: The data were collected from the pathologic reports of pathology laboratories all around the province, during the time period of 1992-2002. Results: ...
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Background: The incidence of oral cancers is different worldwide. Objective: To evaluate the rate of oral cancers in Khouzestan Province. Patients and Methods: The data were collected from the pathologic reports of pathology laboratories all around the province, during the time period of 1992-2002. Results: Among the total received specimens, 305 cases of oral cancers were detected. One hundred ninety-three cases (63.2%) were male and 112 cases (36.8%) were female. Male to female ratio was 1.7 and mean age was 55.04±16.60 years. Squamous cell carcinoma was the most common malignancy (75% of total), and then standed the nasopharyngeal carcinoma (10.8%) and lymphoma (7.5%). The most common sites were lower lip (29.2%), tongue (19%) and nasopharynx (15.7%). Conclusion: Regardless of some minor differences, most of our findings were similar to other previous studies.
Jamalpour Mahdi; Saki Nasrin; Nozari Farnoosh
Abstract
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of unknown etiology. There is evidence that bacteria may contribute to initiating the inflammatory response in HS patients. To date, data on bacteria found in HS lesions and their resistance rates are rare. Methods: The ...
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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of unknown etiology. There is evidence that bacteria may contribute to initiating the inflammatory response in HS patients. To date, data on bacteria found in HS lesions and their resistance rates are rare. Methods: The results of bacterial cultures and antibiotic susceptibility of the isolated bacteria obtained from HS lesions of 26 patients at our dermatology department were analyzed. Results: A total of 50 samples were collected from HS patients. Of the 50 lesional samples, 46 were culture-positive. The 50 lesional samples yielded 61 isolates. The most common isolated bacteria were Staphylococcus aureus, Diphtheroid, and Escherichia coli. Most of the isolates were resistant to penicillin G, followed by erythromycin, clindamycin and ampicillin. The lowest resistant rates were observed for ceftriaxone, imipenem, amikacin, tetracycline, and vancomycin. Conclusions: Due to the low susceptibility rate and antiinflammatory properties, tetracycline may represent as an effective antibiotic agent for therapy in HS patients.
M Farshchian; A Zamanian; M Safakish
Volume 6, Issue 1 , 2002, , Pages 26-31
Abstract
Background: Lichen planus has various clinical and epidemiologic features in different countries. Objectives: To determine clinical and epidemiologic patterns of lichen planus in dermatology department of Hamadan Sina Hospital during a ten-year period. Patients and Methods: This retrospective descriptive ...
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Background: Lichen planus has various clinical and epidemiologic features in different countries. Objectives: To determine clinical and epidemiologic patterns of lichen planus in dermatology department of Hamadan Sina Hospital during a ten-year period. Patients and Methods: This retrospective descriptive study was performed on 363 patients (Including 190 females and 173 males) suffered from lichen planus, referred to Hamadan Sina Hospital, during the years 1991-2001. Data were obtained from patients’ files and were analyzed by EPI6 software. Results: Among 6610 patients who were biopsied, 363 cases (5.5%) were diagnosed as lichen planus. Isolated mucous membrane involvement was observed in 36 patients (9.9%) and 9 patients (2.5%) had both skin and mucous membrane lesions. 318 patients (87.6%) had only skin involvement. The most common site of involvement was face in 71 patients (12.7%). Actinic lichen planus was the most common clinical form of lichen planus, which was seen in 126 patients (36.4%). Conclusion: Among the patients suffering from lichen planus who were biopsied, the face was the most common site of involvement and lichen actinicus was the most common clinical pattern.
Alireza Firooz; Mansour Nassiri-Kashani; Reza Sarhangnejad; Mehdi Rashighi-Firoozabadi; Farzam Gorouhi
Volume 10, Issue 1 , 2007, , Pages 26-31
Abstract
Background and aim: Contact dermatitis is an inflammatory skin response due to contact with environmental materials manifested as acute or chronic eczema. Patch test is the standard test to recognize responsible allergen. The objective of this study was to evaluate the frequency of false positive patch ...
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Background and aim: Contact dermatitis is an inflammatory skin response due to contact with environmental materials manifested as acute or chronic eczema. Patch test is the standard test to recognize responsible allergen. The objective of this study was to evaluate the frequency of false positive patch test responses in patients with Exited Skin Syndrome (ESS).Materials and methods: Fourteen patients older than 12 years with allergic contact dermatitis who had more than one positive reaction in first patch test were re-tested with the same allergens at the time of remission of their eczema. The patches were removed after 48 hours and responses read according to ICDRG guidelines.Results: The patients included 5 men and 9 women with a mean age of 34.92 years. The most common allergens in first patch test were: nickel sulfate (10), cobalt chloride (5), colophony (4), potassium dichromate, PTBF, fragrance mix and MCI/MI (3 each). In the repeated test, the most common positive responses were: nickel (10), cobalt and colophony (4 each), potassium dichromate and fragrance mix (3 each). In 6 of 14 patients the results of second test was different from first one. Three of these patients had active eczema at the time of first test, which in 2 of them one positive response and in one of them, 2 positive responses became negative in second test.Conclusion: It is recommended that patch test be repeated after a while in patients with multiple positive reactions in first test, particularly after remission of active eczema.
