Iranian Journal of Dermatology

Efficacy of excisional surgery, curettage and combined curettage and electrodessication in treatment of basal cell carcinoma

Salmanpoor Rahmatollah; Motevalli Dorna; Saki Nasrin; Saki Maryam

Volume 15, Issue 2 , 2012, , Pages 66-67

Abstract

  .  Read More .

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Acne Keloidalis Nuchae in a White Woman

Kafaie Parichehr; Akaberi Ali Akbar; Hajihoseini Hosein; Binesh Fariba

Volume 12, Issue 2 , 2009, , Pages 69-70

Abstract

  Acne keloidalis is a chronic inflammatory process that involves hair follicles of the nape of the neck and leads to hypertrophic scarring. In all references, it is noticed that this process occurs only in males after puberty and is especially seen in the black race. In this case, we report a 31-year-old ...  Read More Acne keloidalis is a chronic inflammatory process that involves hair follicles of the nape of the neck and leads to hypertrophic scarring. In all references, it is noticed that this process occurs only in males after puberty and is especially seen in the black race. In this case, we report a 31-year-old white woman who had hypertrophic papules in the nape of her neck since 10 years ago and in pathological examination, the diagnosis of acne keloidalis was confirmed.

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Multidermatomal nevus comedonicus: A case report

Barzegar Mohamad Reza; Golfeshan Atefe

Volume 18, Issue 2 , 2015, , Pages 74-76

Abstract

  Nevus comedonicus is an uncommon variant of adnexal hamartoma and is considered a rare subtype of epidermal nevi. It was first described in 1895 by Kofmann who used the term “comedo-nevus”. It manifests as a group of closely dilated follicular openings with dark keratin plugs resembling comedones. ...  Read More Nevus comedonicus is an uncommon variant of adnexal hamartoma and is considered a rare subtype of epidermal nevi. It was first described in 1895 by Kofmann who used the term “comedo-nevus”. It manifests as a group of closely dilated follicular openings with dark keratin plugs resembling comedones. Both unilateral and bilateral distributions are seen. The face is the most commonly affected site followed by the neck, the trunk, and the upper arms. We report a case of a 25-year-old male who presented with linear keratotic papules which on histopathology was confirmed to be nevus comedonicus. Our case was interesting because of its large size and of its multidermatomal involvement affecting the chest, back, and arms.

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Acquired hyperpigmented lesion on the foot

Pouran Layegh; Nona Zabolinejad; Naghmeh Zabolinejad; Akram Momenzadeh

Volume 14, Issue 2 , 2011, , Pages 76-78

Abstract

  case: A 3.5-year-old girl presented with a 1-year history of a slow growing pigmented lesion on the dorsal aspect of her right foot. Physical examination revealed the presence of a pigmented patch with color distribution from pink to tan to dark brown, relatively well circumscribed and approximately ...  Read More case: A 3.5-year-old girl presented with a 1-year history of a slow growing pigmented lesion on the dorsal aspect of her right foot. Physical examination revealed the presence of a pigmented patch with color distribution from pink to tan to dark brown, relatively well circumscribed and approximately 1.5 × 2cm with irregular borders, and especially a single dark central papule superimposed in the middle of it (Figure 1). The lesion had a soft consistency and the child did not have any other symptoms. During the last year, it had increased in dimensions and thickness. The remainder of her physical examination was insignificant. Also, there was no positive family history of a particular disease or any history of trauma or drug usage. A 3 mm punch biopsy was obtained from the central dark papule and the specimen was sent for histopathologic examination.

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Post nuclear crisis: what about the mucocutaneous problem?

Joob Beuy; Wiwanitkit Viroj

Volume 17, Issue 2 , 2014, , Pages 79-79

Abstract

  Health problems after a nuclear crisis are aninteresting issue in medicine. After the recentJapanese nuclear crisis, several health issuesunderwent monitoring. There are few considerationson mucocutaneous diseases. Indeed, there is nodoubt that the skin and mucocutaneous issues arethe main organs affected ...  Read More Health problems after a nuclear crisis are aninteresting issue in medicine. After the recentJapanese nuclear crisis, several health issuesunderwent monitoring. There are few considerationson mucocutaneous diseases. Indeed, there is nodoubt that the skin and mucocutaneous issues arethe main organs affected by leaked radiations. It isimportant to take care of mucocutaneous lesionsin acute radiation syndrome.

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Elastosis Perforans Serpiginosa: A Case Report

Malekzad Farhad; Sarlak Mojdeh

Volume 11, Issue 2 , 2008, , Pages 89-91

Abstract

  We report a 61-year-old man with multiple colored skin papules with central crusts in an archiform and linear pattern on his forehead as well as verrucus and hyperkeratotic plaques with central perforation on hands. Histologic examination of the lesions demonstrated a narrow channel of epidermal perforation ...  Read More We report a 61-year-old man with multiple colored skin papules with central crusts in an archiform and linear pattern on his forehead as well as verrucus and hyperkeratotic plaques with central perforation on hands. Histologic examination of the lesions demonstrated a narrow channel of epidermal perforation containing notrophils, basophilic debris and elastic fibers with eosinophilic degeneration compatible with the diagnosis of elastosis perforans serpiginosa.

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A Young Adult with Myoclonic Seizure

Reza Mahmoud Robati; Zahra Asadi Kani; Mehdi Qeisari

Volume 12, Issue 3 , 2009, , Pages 103-104

Abstract

  A 21-year-old man was referred to dermatology clinic for skin biopsy. He presented to neurology center with behavioral changes with cognition and memory disorders. He had two episodes of genealized tonic clonic seizure and series of myoclonc jerks in his limbs and face especially after awakening since ...  Read More A 21-year-old man was referred to dermatology clinic for skin biopsy. He presented to neurology center with behavioral changes with cognition and memory disorders. He had two episodes of genealized tonic clonic seizure and series of myoclonc jerks in his limbs and face especially after awakening since several months ago. In neurological examination, he had mini mental score as 13; with some degree of bradykinesia, limb rigidity and dysartheria. He had leaved school because of inability to learning. His sister had died 5 months ago from the same disease. We performed biopsy from his right axillary skin. Histopathological examination revealed multiple intracytoplasmic homogenous pale basophilic globi in apocrine glands acini which were showing PAS positive reactivity in special staining. Reminder of epidermis and mid reticular dermis was unremarkable.

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Amniotic Band Syndrome with the Involvement of Trunk: A Case Report

Hajihosseini Hossein; Amini Seyed Saeed

Volume 13, Issue 3 , 2010, , Pages 103-104

Abstract

  Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, ...  Read More Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, including the hand. We report a case of constriction amniotic bands involving the trunk.

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Indeterminate cell histiocytosis: a case report

Soltanieh Elahe; Farshchian Mahmood; Dehqan Arash; Mousavi Leila

Volume 15, Issue 3 , 2012, , Pages 105-108

Abstract

  Indeterminate cell histiocytosis is a very rare proliferative disorderof histiocytes which displays both langerhans cell histiocytosisand non langerhans cell histiocytosis immunophenotypic features.The majority of the patients develop multiple lesions which areclinically indistinguishable from generalized ...  Read More Indeterminate cell histiocytosis is a very rare proliferative disorderof histiocytes which displays both langerhans cell histiocytosisand non langerhans cell histiocytosis immunophenotypic features.The majority of the patients develop multiple lesions which areclinically indistinguishable from generalized eruptive histiocytosis.We report a 14-year-old girl with multiple papules on the face,scalp and trunk.

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Multiple firm, reddish-brown papules and nodules on shoulder and arm

Farideh Jowkar; Fatemeh Sari Aslani; Nasrin Saki; Sina Kardeh; Maryam Sadat Sadati

Volume 17, Issue 3 , 2014, , Pages 114-116

Abstract

    Read More

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A young woman with multiple hypopigmented patches

Robati Reza; Ebadi Atyeh; Nazari Sajjad; Saffarian Zahra

Volume 14, Issue 3 , 2011, , Pages 117-118

Abstract

  A 33–year-old woman was visited at the dermatological clinic of Loghman-e-Hakim Hospital with multiple hypopigmented patches on her right arm, buttocks and flanks. Her lesions developed over the past year with no regression. Lesions were resistant to multiple antifungal therapies. Clinical examination ...  Read More A 33–year-old woman was visited at the dermatological clinic of Loghman-e-Hakim Hospital with multiple hypopigmented patches on her right arm, buttocks and flanks. Her lesions developed over the past year with no regression. Lesions were resistant to multiple antifungal therapies. Clinical examination revealed multiple circular or oval patches on the right arm, flank and sacral area. There was no erythema but fine scales were observed on the lesions (Figure1). No cutaneous sensory deficit was detected and no abnormality was found on physical examination. Also, there was no family history of similar problems. Abdominal ultrasonography and chest x-ray were normal. We performed biopsy from one of the lesions.

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Evaluation of Licorice efficacy on melasma

Toossi Parviz; Esmaili-Azad Mitra; Saeedi Mohammad

Volume 16, Issue 3 , 2013, , Pages 118-119

Abstract

  Treatment of melasma has remained a hottopic in dermatology because of its resistance totherapy and high recurrence rate. For many yearshydroquinone was the foundation of melasmatreatment, but its use has been limited during theseyears due to a number of adverse events, suchas skin irritation, hyper ...  Read More Treatment of melasma has remained a hottopic in dermatology because of its resistance totherapy and high recurrence rate. For many yearshydroquinone was the foundation of melasmatreatment, but its use has been limited during theseyears due to a number of adverse events, suchas skin irritation, hyper and hypo pigmentation,nail discoloration, conjunctival melanosis andochronosis. Furthermore hydroquinone is quiteunstable and is quickly oxidized and becomeinactive. So Hydroquinone is gradually beingreplaced by new lightning substances, such as kojicacid, phytic acid, azaleic acid, arbutin, mequinol,aleosin, ascorbic acid, soya proteins, N-acetylglucosamine and licorice. In this study weevaluate the effect of a licorice containing product(lightening serum, LANGE Paris) for the treatmentof melasma. There are several active ingredientsin licorice extract effective on melasma. These areliquiritin, glabridin, licochalcone A and isoliquertin.

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Clinical and laboratory findings in 45 patients with cutaneous Tuberculosis in Ahwaz

S Rasaei

Volume 8, Issue 2 , 2005, , Pages 121-127

Abstract

  Background: Cutaneous granulomatous dermatoses usually are a diagnostic challenge with tuberculosis (TB) on top of them. TB is a universal health problem and considered by WHO at the top of 6 common and dangerous infectious diseases. Objective: To determine the clinical, laboratory and histopathological ...  Read More Background: Cutaneous granulomatous dermatoses usually are a diagnostic challenge with tuberculosis (TB) on top of them. TB is a universal health problem and considered by WHO at the top of 6 common and dangerous infectious diseases. Objective: To determine the clinical, laboratory and histopathological findings in 45 patients with the diagnosis of cutaneous TB over a 10-year period in Ahwaz. Patients and Methods: This is an existing data study on the records of all patients with the diagnosis of TB admitted to Sina hospital in Ahwaz from November 1990 to March 1999. Data on the age, localization, clinical features were extracted from hospital records. Results: The age range of patients was between 1-76 years. Twenty-eight cases were female and 17 cases were male. Twenty-three cases were clinically diagnosed as scrofuloderma (SFD), 18 cases as lupus vulgaris (LV), 1 case as erythema induratum, 1 case as TB gumma, 1 case as orificial TB and 1 case as populonecrotic tuberculide. The most common involved site was face and the least common sites of involvement were buttock and elbow. Six cases had positive family history. SFD was present in 12 females and 11 males. The result of tuberculin test was positive in 15, negative in 17 and not available in 13 patients. Histopathologically, 23 cases showed chronic granulomatous disease without caseation, 18 cases showed non-specific inflammation and in 3 cases tubercle with caseation was observed. Concerning treatment, we found generally good clinical response with no failure in 32 patients who came for follow up. Conclusions: This study showed that in Ahwaz SFD was the most common form of cutaneous TB and the most frequent site of involvement was face.

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Thermal therapy with radiofrequency for the treatment of basal cell carcinoma: a pilot study

Leila I Izadi Firouzabadi; Hamidreza Mahmoudi; Ali Khamesipour; Abhay Satoskar; Alireza Firooz

Volume 24, Issue 2 , June 2021, , Pages 121-126

https://doi.org/10.22034/ijd.2020.250152.1226

Abstract

  Background: Basal cell carcinoma (BCC) is the most common type of skin malignancy. Hyperthermia is used as adjuvant therapy together with radiotherapy and chemotherapy in the treatment of some cancers. This study aimed to evaluate the efficacy and safety of thermotherapy in the treatment of BCCs. Methods: ...  Read More Background: Basal cell carcinoma (BCC) is the most common type of skin malignancy. Hyperthermia is used as adjuvant therapy together with radiotherapy and chemotherapy in the treatment of some cancers. This study aimed to evaluate the efficacy and safety of thermotherapy in the treatment of BCCs. Methods: This pilot trial was carried out on five patients with nodular or superficial BCCs on the scalp and face.Thermotherapy was done at 50° C for a duration of 30 seconds with a radiofrequency device (Thermomed 1.8 thermosurgery technologies). Thermotherapy treatment was applied only in one session. The first follow-up was one week after the procedure and then every month for six months. The last follow-up was one year after the procedure. Results: All patients showed clearance of the tumors. Blisters, ulcers, crusts, and necrosis were the side effects, which healed with acceptable degrees of scarring. No recurrence was observed at the end of the study. Conclusion: Thermotherapy was safe and efficacious for the treatment of BCCs on the scalp and face. It should be considered especially for the low-risk subtypes of this cancer.

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CASE 1

Suzan Kavusi; Vahide Lajevardi; Fateme Moinedin; Mohamad Reza Barzegar

Volume 11, Issue 3 , 2008, , Pages 133-134

Abstract

  A 10-year-old girl presented with a 1-year history of an eruption on her hands. Physical examination revealed soft, bluish slightly tender subcutaneous nodules and swellings in the ulnar site and palmar aspect of five fingers of the right hand and dorsal aspect of three fingers of the left hand without ...  Read More A 10-year-old girl presented with a 1-year history of an eruption on her hands. Physical examination revealed soft, bluish slightly tender subcutaneous nodules and swellings in the ulnar site and palmar aspect of five fingers of the right hand and dorsal aspect of three fingers of the left hand without any gross deformity in fingers and long bones (figure 1). History of pathological fractures was negative. X ray of the right hand showed reduction in bone density with lytic lesions in five metacarps and proximal phalanx of the fourth and fifth fingers associated with soft tissue swellings (figure 2). A biopsy specimen was taken from a skin nodule (figure 3).

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Lichenoid and granulomatous dermatitis: Report of two cases from Iran

Ghasemibasir Hamidreza; Khezrian Leila; Sobhan Mohammad Reza

Volume 18, Issue 3 , 2015, , Pages 136-139

Abstract

  Lichenoid and granulomatous dermatitis is a new entity which is histologically defined by a band like lymphocytic infiltration in the upper portion of the dermis with obscuring the dermoepidermal junction and accompanied by basal layer degeneration and granulomatous inflammation. Herein, we presented ...  Read More Lichenoid and granulomatous dermatitis is a new entity which is histologically defined by a band like lymphocytic infiltration in the upper portion of the dermis with obscuring the dermoepidermal junction and accompanied by basal layer degeneration and granulomatous inflammation. Herein, we presented two Iranian women with similar cutaneous and histopathologic findings. Both patients had asymptomatic subcutaneous nodules on their hands. The pathological manifestation in both of them was lichenoid and granulomatous dermatitis. Our investigations indicated different underlying causes of the lesions in our patients. In one patient, the lesion was associated with hyperthyroidism and in the other one it was accompanied by rheumatoid arthritis.

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The Effectiveness of the Extract of Serenoa Repens (Saw Palmetto) In Idiopathic Facial Hirsutism

Yousefi Maryam; Barikbin Behrooz; Givrad Soudabeh; Moravvej Hamideh; Khoshnoudi Roxanna

Volume 12, Issue 4 , 2009, , Pages 139-140

Abstract

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Macrolides in dermatology

Ehsani Amir Houshang; Hosseini Mahboobeh-Sadat; Lajvardi Vahideh-Sadat

Volume 10, Issue 2 , 2007, , Pages 142-156

Abstract

  Erythromycin was the first macolide discovered in 1952. In 1990s new macrolides including clarithromycin, azithromycin, and dirithromycin were introduced to the market. We provide a review of their structure, pharmacokinetics, mechanisms of action, and indications in dermatology.  Read More Erythromycin was the first macolide discovered in 1952. In 1990s new macrolides including clarithromycin, azithromycin, and dirithromycin were introduced to the market. We provide a review of their structure, pharmacokinetics, mechanisms of action, and indications in dermatology.

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Brown Discoloration on the Face

Ladan Dastgheib; Fateme Sari Aslani; Hoda Ghoreishi

Volume 13, Issue 4 , 2010, , Pages 142-143

Abstract

  Case: A 54-year-old woman was visited with a history of asymptomatic gray-brown discoloration of the facial skin at our dermatology clinic. The lesions first appeared on her chin and then became progressively darker and extended to her nose and, to a lesser extent, to the periphery of her face over a ...  Read More Case: A 54-year-old woman was visited with a history of asymptomatic gray-brown discoloration of the facial skin at our dermatology clinic. The lesions first appeared on her chin and then became progressively darker and extended to her nose and, to a lesser extent, to the periphery of her face over a period of five years. She mentioned that the lesions worsened with heat and sun exposure. Her past medical history was unremarkable. The patient’s medications included sunscreens, and hydroquinone lightening creams from many years ago. Physical examination revealed a previous depressed scar of cutaneous leishmaniasis on her forehead, brown to black hyperpigmented macules and patches, more in her midface area, especially the nose and chin, with superimposed small pigmented papules scattered on normal and hyperpigmented facial skin (Figures 1,2). She had no discoloration on other body sites such as the neck, hands or trunk and there was no evidence of arthritis or joint pain. The complete blood cell count, urine analysis and creatinin levels were normal.

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Liquorice 7% versus selenium sulfide 1% shampoos in the treatment of dandruff: a clinical trial

Salmanpoor Rahmatollah; Saki Nasrin; Mahmoodi Gholamreza

Volume 15, Issue 4 , 2012, , Pages 144-145

Abstract

    Read More

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Kaposi’s varicelliform eruption: a case report

Paik Sabyasachi; Pal Agnik; Sukanta Sen; Gautam Banerjee; Santanu Tripathi

Volume 17, Issue 4 , 2014, , Pages 144-145

Abstract

  Kaposi’s varicelliform eruption (KVE) is a typeof skin disorder caused mainly byherpes simplex virus (HSV) type 1 and2 and occasionally by coxsackie A 16 and vacciniavirus, which is commonly found in the second andthird decades of life. It is predominantly associatedwith atopic dermatoses. Therefore, ...  Read More Kaposi’s varicelliform eruption (KVE) is a typeof skin disorder caused mainly byherpes simplex virus (HSV) type 1 and2 and occasionally by coxsackie A 16 and vacciniavirus, which is commonly found in the second andthird decades of life. It is predominantly associatedwith atopic dermatoses. Therefore, it is also termedeczema herpeticum (EH) 1. Herein, we report acase of Kaposi’s varicelliform eruption triggeredby HSV infection.

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Comparison of relative frequency of basal cell carcinoma in 1368-69 and 1378-79, in Razi Hospital, Tehran

M Barzegari; Z Safaei Naraghi; M Akhyani; AH Ehsani; R Mahmoud Robati; S Bagheri Nejad

Volume 9, Issue 2 , 2006, , Pages 159-164

Abstract

  Background and aim:Basal cell carcinoma (BCC) is the most common cancer in whites. The most important risk factor for developing BCC is solar ultraviolet (UV) irradiation. As the weather in most parts of Iran is mostly sunny, BCC is common. This study was performed to evaluate changes in the frequency ...  Read More Background and aim:Basal cell carcinoma (BCC) is the most common cancer in whites. The most important risk factor for developing BCC is solar ultraviolet (UV) irradiation. As the weather in most parts of Iran is mostly sunny, BCC is common. This study was performed to evaluate changes in the frequency of BCC in 1368-69 and 1378-79.Materials and Methods: This descriptive and retrospective study was performed as an existing data study and all files in department of pathology in Razi Hospital from 1368-69 and 1378-79 were assessed with regards of BCC frequency, patient age and gender as well as history of radiation and the collected data were compared.Results: A total of 1503 BCCs were studied, 507 were from 1368-69 and 996 from 1378-79 period. In the years 1368-69, relative frequency of BCC was 11.1%. On the other hand in years 1378-79 relative frequency of BCC was increased to 15.2%, which was not associated with gender. BCC occurance showed a significant decrease in 20-30-year age group and a significant increase in over 60 years age group. Among histologic subtypes, nodular form showed an increase, which was statistically significant on face region (P<0.005), but was not linked to patient gender. In male patients significant decrease of BCC frequency on face and increase on head and neck areas was observed, but there was not any significant change in tumor location in female patients.Conclusion:During a 10-year period the frequency of BCC has increased significantly requiring more attention to develop educational programs regarding prevention, diagnosis and early treatment.

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Bilateral indurated violaceous non-tender plaques on the nasal ala

Qeisari Mehdi; Zerehpoosh Farahnaz Bidari; Abdollahimajd Fahmimeh; Salajeghe Sara

Volume 16, Issue 4 , 2013, , Pages 165-167

Abstract

  A 77-year-old Iranian man was visited at the Dermatology Department of Loghman-e Hakim Hospital affiliated with Shahid Beheshti University of Medical Sciences on June 2012 with bilateral, symmetric, raised, violaceous and painless plaques on the nose (both ala nasi), from one year ago. The lesions were ...  Read More A 77-year-old Iranian man was visited at the Dermatology Department of Loghman-e Hakim Hospital affiliated with Shahid Beheshti University of Medical Sciences on June 2012 with bilateral, symmetric, raised, violaceous and painless plaques on the nose (both ala nasi), from one year ago. The lesions were small at first and then grew gradually larger in size. Systemic symptoms such as fever, weight loss and night sweat were absent. He had no history of systemic disease, bite, trauma, vaccination, or medication. Past medical history was negative except for cataract in several years ago and he was in good health. He had a history of treatment with oral antibiotics without any improvement. Physical examination revealed bilateral, symmetric, indurated, violaceous, non-tender plaques on the nose (both ala nasi) with some scales and follicular accentuation without discharge (Figure 1). Other examinations were normal and laboratory tests revealed no abnormality. A skin biopsy was performed.

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Pseudoxanthoma Elasticum: A Report of Three Cases in a Family

Omidian Mohammad; Mapar Mohammad Ali; Hashemzadeh Sara; Mostofi Nepton

Volume 11, Issue 4 , 2008, , Pages 173-175

Abstract

  Pseudoxanthoma Elasticum is an inherited disorder characterized by generalized fragmentation and progressive calcification of the elastic tissues in the dermis, blood vessels and Bruch’s membrane of the eye. Herein, we report 3 patients in a family with pseudoxanthoma elasticum: a father and his ...  Read More Pseudoxanthoma Elasticum is an inherited disorder characterized by generalized fragmentation and progressive calcification of the elastic tissues in the dermis, blood vessels and Bruch’s membrane of the eye. Herein, we report 3 patients in a family with pseudoxanthoma elasticum: a father and his two sons.

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Spectacle frame induced chemical leucoderma: A case report

Gupta Mrinal; Gupta Heena; Gupta Anish

Volume 18, Issue 4 , 2015, , Pages 184-186

Abstract

  Chemical leucoderma is an acquired hypopigmented dermatosis caused by repeated exposure to specific chemical compounds, notably the aromatic or aliphatic derivatives of phenols andcatechols which are commonly present in the rubber and plastic materials. Herein, we report a case of chemical leucoderma ...  Read More Chemical leucoderma is an acquired hypopigmented dermatosis caused by repeated exposure to specific chemical compounds, notably the aromatic or aliphatic derivatives of phenols andcatechols which are commonly present in the rubber and plastic materials. Herein, we report a case of chemical leucoderma in a 55-year-old male, appearing bilaterally over the retroauricular areas, which appeared after of the use of a new spectacle frame by the patient. The patch test results with Indian Standard Series and Cosmetic Series were negative. Chemical leucoderma following the use of materials like hair dyes, and rubber shoes or gloves is common but only a few cases of leucoderma with spectacles have been reported in the literature to date.

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